{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Abnormality&page=2",
    "query": {
      "condition": "Craniofacial Abnormality",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Abnormality&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T14:15:16.892Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03025763",
      "title": "Network Of Clinical Research Studies On Craniosynostosis, Skull Malformations With Premature Fusion Of Skull Bones",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Craniosynostosis"
      ],
      "interventions": [
        {
          "name": "Craniosynostosis Network Environmental Survey",
          "type": "OTHER"
        },
        {
          "name": "2D/3D Photography",
          "type": "OTHER"
        },
        {
          "name": "Buccal Swab Cell Sampling",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood sampling",
          "type": "PROCEDURE"
        },
        {
          "name": "Skin Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Tissues from a Clinically Indicated Procedure",
          "type": "PROCEDURE"
        },
        {
          "name": "Pre-operative CT Scan Image Files.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "Up to 80 Years"
      },
      "enrollment_count": 2145,
      "start_date": "2015-01-13",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2025-01-02",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 15,
      "location_summary": "Davis, California • Hartford, Connecticut • Chicago, Illinois + 10 more",
      "locations": [
        {
          "city": "Davis",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03025763"
    },
    {
      "nct_id": "NCT02330016",
      "title": "Juvederm Voluma® XC for the Treatment of Hypoplastic Chin",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Mandibular Hypoplasia"
      ],
      "interventions": [
        {
          "name": "Voluma XC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kenneth Beer",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2014-12",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2015-06-18",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "West Palm Beach, Florida",
      "locations": [
        {
          "city": "West Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02330016"
    },
    {
      "nct_id": "NCT00004639",
      "title": "Cleft Palate Surgery and Speech Development",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [
        {
          "name": "Furlow double z-plasty palatoplasty palate repair",
          "type": "PROCEDURE"
        },
        {
          "name": "Von Langenbeck palatoplasty palate repair",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 475,
      "start_date": "1996-02",
      "completion_date": "2007-04",
      "has_results": false,
      "last_update_posted_date": "2011-09-20",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00004639"
    },
    {
      "nct_id": "NCT03539601",
      "title": "A Study of Crisaborole Ointment 2%; Crisaborole Vehicle; TCS and TCI in Subjects Aged ≥ 2 Years, With Mild-moderate AD",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Atopic Dermatitis"
      ],
      "interventions": [
        {
          "name": "Crisaborole ointment, 2%",
          "type": "DRUG"
        },
        {
          "name": "Hydrocortisone butyrate cream, 0.1%",
          "type": "DRUG"
        },
        {
          "name": "Pimecrolimus cream, 1%",
          "type": "DRUG"
        },
        {
          "name": "Crisaborole Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 237,
      "start_date": "2018-04-27",
      "completion_date": "2020-12-11",
      "has_results": true,
      "last_update_posted_date": "2022-01-10",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 10,
      "location_summary": "Bryant, Arkansas • Encinitas, California • Orange Park, Florida + 7 more",
      "locations": [
        {
          "city": "Bryant",
          "state": "Arkansas"
        },
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "Orange Park",
          "state": "Florida"
        },
        {
          "city": "Sweetwater",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03539601"
    },
    {
      "nct_id": "NCT01380171",
      "title": "Primary Palatoplasty in Pediatric Patients - A Retrospective Review of Surgical Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cleft Lip",
        "Cleft Palate"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Children's Healthcare of Atlanta",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 1295,
      "start_date": "2007-02",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2011-06-27",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01380171"
    },
    {
      "nct_id": "NCT06284434",
      "title": "Liposomal Bupivacaine Use in Alveolar Bone Graft Patients",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cleft Lip and Palate"
      ],
      "interventions": [
        {
          "name": "Liposomal Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacain",
          "type": "DRUG"
        },
        {
          "name": "Epinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kerry O'Rourke",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-04-24",
      "completion_date": "2026-04-24",
      "has_results": false,
      "last_update_posted_date": "2024-07-03",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06284434"
    },
    {
      "nct_id": "NCT05492266",
      "title": "Expiratory Muscle Strength Training for Hypernasal Speech in Children",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Velopharyngeal Insufficiency",
        "Velopharyngeal Incompetence Due to Cleft Palate",
        "Inadequate Velopharyngeal Closure",
        "Palatopharyngeal Incompetence",
        "Hypernasality"
      ],
      "interventions": [
        {
          "name": "Expiratory Muscle Strength Training",
          "type": "DEVICE"
        },
        {
          "name": "Maintenance Training",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Noel Jabbour",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "5 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-03-03",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05492266"
    },
    {
      "nct_id": "NCT01144741",
      "title": "Survey Study and Records Review of Treatment Outcomes in Freeman-Sheldon Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Freeman-Sheldon Syndrome",
        "Arthrogryposis Distal Type 2A",
        "Whistling Face Syndrome",
        "Craniocarpotarsal Dysplasia",
        "Craniocarpotarsal Dystrophy",
        "Freeman-Sheldon Syndrome Variant",
        "Sheldon-Hall Syndrome",
        "Arthrogryposis Distal Type 2B",
        "Gordon Syndrome",
        "Arthrogryposis Distal Type 3",
        "Arthrogryposis Distal Type 1",
        "Arthrogryposis, Distal, Type 1A",
        "Arthrogryposis Distal Type 1B",
        "Arthrogryposis, Distal",
        "Craniofacial Abnormalities",
        "Arthrogryposis"
      ],
      "interventions": [
        {
          "name": "PTSD Checklist-Civilian (PCL-C)",
          "type": "OTHER"
        },
        {
          "name": "Modified Flanagan Quality of Life Scale",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiologic Studies Depression Scale (CES-D)",
          "type": "OTHER"
        },
        {
          "name": "Functional Enquiry (or Review of Systems) Form",
          "type": "OTHER"
        },
        {
          "name": "Study of Therapeutic Outcomes and Practices in Freeman-Sheldon Syndrome (STOP-FSS) Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "FSRG Semi-Structured Quality of Life Interview (FSRG SSQLI)",
          "type": "OTHER"
        },
        {
          "name": "Medical Records Review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Freeman-Sheldon Research Group, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 2,
      "start_date": "2010-02",
      "completion_date": "2022-06-14",
      "has_results": false,
      "last_update_posted_date": "2022-06-21",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Buckhannon, West Virginia",
      "locations": [
        {
          "city": "Buckhannon",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01144741"
    },
    {
      "nct_id": "NCT02261857",
      "title": "3D-Printed CPAP Masks for Children With Obstructive Sleep Apnea",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Sleep Apnea, Obstructive",
        "Craniofacial Abnormalities",
        "Pediatric Disorder"
      ],
      "interventions": [
        {
          "name": "Personalized continuous positive airway pressure (CPAP) mask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Glenn Green",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "1 Year to 18 Years"
      },
      "enrollment_count": 8,
      "start_date": "2013-09",
      "completion_date": "2017-09",
      "has_results": false,
      "last_update_posted_date": "2020-04-16",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02261857"
    },
    {
      "nct_id": "NCT01322165",
      "title": "National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Marfan Syndrome",
        "Turner Syndrome",
        "Ehlers-Danlos Syndrome",
        "Loeys-Dietz Syndrome",
        "FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation",
        "Bicuspid Aortic Valve Without Known Family History",
        "Bicuspid Aortic Valve With Family History",
        "Bicuspid Aortic Valve With Coarctation",
        "Familial Thoracic Aortic Aneurysm and Dissections",
        "Shprintzen-Goldberg Syndrome",
        "Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo",
        "Other Congenital Heart Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3706,
      "start_date": "2007-11",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2016-12-20",
      "last_synced_at": "2026-09-28T14:15:16.892Z",
      "location_count": 7,
      "location_summary": "Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more",
      "locations": [
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01322165"
    }
  ]
}