{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Injuries",
    "query": {
      "condition": "Craniofacial Injuries"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 20,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Craniofacial+Injuries&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T18:48:24.839Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01889381",
      "title": "Human Craniomaxillofacial Allotransplantation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Facial Injuries",
        "Traumatic Wounds and Injuries",
        "Craniofacial Injuries",
        "Craniofacial Defects",
        "Facial Transplantation",
        "Facial Deformity"
      ],
      "interventions": [
        {
          "name": "Bone marrow cell-based therapy & 1-drug immunosuppression.",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2012-08",
      "completion_date": "2031-08",
      "has_results": false,
      "last_update_posted_date": "2025-08-14",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01889381"
    },
    {
      "nct_id": "NCT01307475",
      "title": "Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthrogryposis",
        "Craniofacial Abnormalities",
        "Posttraumatic Stress Disorder",
        "Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "PTSD Checklist-Specific",
          "type": "OTHER"
        },
        {
          "name": "Modified Flanagan Quality of Life Scale",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiologic Studies Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Functional Enquiry Form",
          "type": "OTHER"
        },
        {
          "name": "Strength, Joint ROM, Girth and Length Measurements",
          "type": "OTHER"
        },
        {
          "name": "Study Physical Examination",
          "type": "OTHER"
        },
        {
          "name": "PTSD, Depression, and FSS-Focused Examination",
          "type": "OTHER"
        },
        {
          "name": "Freeman-Sheldon Specific Quality of Life Survey",
          "type": "OTHER"
        },
        {
          "name": "Lactate, Glucose, and Adenosine Triphosphate Blood Levels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Freeman-Sheldon Research Group, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6,
      "start_date": "2011-02",
      "completion_date": "2017-04-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Buckhannon, West Virginia",
      "locations": [
        {
          "city": "Buckhannon",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01307475"
    },
    {
      "nct_id": "NCT01616953",
      "title": "Cell Therapy for Craniofacial Bone Defects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cleft Palate",
        "Trauma"
      ],
      "interventions": [
        {
          "name": "Ixmyelocel-T",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Autogenous Bone Grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 18,
      "start_date": "2012-08",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2017-05-04",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01616953"
    },
    {
      "nct_id": "NCT05205616",
      "title": "Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Complication",
        "Paresthesia",
        "Fracture",
        "Nerve Injury",
        "Nerve Entrapments",
        "Mandibular Nerve Injuries",
        "Mandibular Hypoplasia",
        "Mandibular Retrognathism",
        "Mandibular Hyperplasia",
        "Mandibular Prognathism"
      ],
      "interventions": [
        {
          "name": "Sonopet ultrasonic saw",
          "type": "DEVICE"
        },
        {
          "name": "Reciprocating saw",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "Up to 45 Years"
      },
      "enrollment_count": 32,
      "start_date": "2021-07-20",
      "completion_date": "2023-07-25",
      "has_results": true,
      "last_update_posted_date": "2025-06-04",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05205616"
    },
    {
      "nct_id": "NCT03872544",
      "title": "Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wound; Head, Multiple",
        "Wound; Head, Scalp",
        "Wound; Head",
        "Wound Infection",
        "Wound Complication",
        "Wound Dehiscence",
        "Wound of Skin",
        "Wound Open",
        "Wounds, Penetrating",
        "Wounds, Nonpenetrating",
        "Wounds and Injuries",
        "Wounds",
        "Disturbance of Wound Healing",
        "Facial Bones Fracture",
        "Soft Tissue Injuries",
        "Skull Fractures",
        "Surgical Wound",
        "Surgical Wound Infection",
        "Wound Healing"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dufresne, Craig, MD, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2023-09-20",
      "completion_date": "2025-11-11",
      "has_results": false,
      "last_update_posted_date": "2022-06-16",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03872544"
    },
    {
      "nct_id": "NCT03880188",
      "title": "Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wounds and Injuries",
        "Wound Infection",
        "Facial Bones Fracture",
        "Soft Tissue Injuries",
        "Skull Fractures",
        "Surgical Wound",
        "Surgical Wound Infection",
        "Wound Healing",
        "Disturbance of Wound Healing",
        "Wound; Head, Multiple",
        "Wound; Head, Scalp",
        "Wound; Head",
        "Wound Complication",
        "Wound Dehiscence",
        "Wound of Skin",
        "Wound Open",
        "Wounds, Penetrating",
        "Wounds, Nonpenetrating",
        "Wounds"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dufresne, Craig, MD, PC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2022-09-10",
      "completion_date": "2024-06-30",
      "has_results": false,
      "last_update_posted_date": "2022-06-16",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Fairfax, Virginia",
      "locations": [
        {
          "city": "Fairfax",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03880188"
    },
    {
      "nct_id": "NCT07154667",
      "title": "Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Microtia, Congenital",
        "Microtia",
        "Microtia-Anotia",
        "Ear Deformities, Acquired",
        "Ear Deformity External",
        "Ear Malformation",
        "Ear Cartilage"
      ],
      "interventions": [
        {
          "name": "Use of AuryzoN™ EAR 2.0 device",
          "type": "PROCEDURE"
        },
        {
          "name": "Hand carving",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "5 Years to 20 Years"
      },
      "enrollment_count": 30,
      "start_date": "2025-10-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-29",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07154667"
    },
    {
      "nct_id": "NCT03698838",
      "title": "Myelin Imaging Changes In Patients With Neurosurgical Diseases",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hydrocephalus in Children",
        "Epilepsy",
        "Craniosynostoses",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "McDESPOT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Memorial Healthcare System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "Up to 19 Years"
      },
      "enrollment_count": 20,
      "start_date": "2019-02-12",
      "completion_date": "2020-07-15",
      "has_results": false,
      "last_update_posted_date": "2020-09-02",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Hollywood, Florida",
      "locations": [
        {
          "city": "Hollywood",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03698838"
    },
    {
      "nct_id": "NCT01633892",
      "title": "Use of Concentrated Endogenous Autologous Adipose Stromal Cells in Fat Grafts for Craniofacial Trauma",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Craniofacial Injuries"
      ],
      "interventions": [
        {
          "name": "Fat Grafting",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2012-06",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2017-08-03",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01633892"
    },
    {
      "nct_id": "NCT03325946",
      "title": "The FBRI VTC Neuromotor Research Clinic",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Neuromotor Impairments",
        "Cerebral Palsy",
        "Microcephaly",
        "Autism",
        "Trauma, Brain",
        "Acquired Brain Injury",
        "Pediatric Stroke"
      ],
      "interventions": [
        {
          "name": "ACQUIRE Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Polytechnic Institute and State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "3 Months",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "3 Months to 18 Years"
      },
      "enrollment_count": 500,
      "start_date": "2013-01-01",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-07-22T18:48:24.839Z",
      "location_count": 1,
      "location_summary": "Roanoke, Virginia",
      "locations": [
        {
          "city": "Roanoke",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03325946"
    }
  ]
}