{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Critically-ill&page=2",
    "query": {
      "condition": "Critically-ill",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Critically-ill&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-23T01:53:26.236Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02721810",
      "title": "Patient Engagement Initiative",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Consideration of 3-month functional prognosis",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "25 Years and older"
      },
      "enrollment_count": 116,
      "start_date": "2016-10",
      "completion_date": "2019-03-19",
      "has_results": false,
      "last_update_posted_date": "2019-05-20",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02721810"
    },
    {
      "nct_id": "NCT01777035",
      "title": "Early Mobilization in the ICU",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Failure"
      ],
      "interventions": [
        {
          "name": "early PT OT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2011-07-19",
      "completion_date": "2022-01-14",
      "has_results": false,
      "last_update_posted_date": "2022-02-21",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01777035"
    },
    {
      "nct_id": "NCT01933789",
      "title": "Improving Communication About Serious Illness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Chronic Disease",
        "Terminal Care",
        "Palliative Care",
        "Communication",
        "Advance Care Planning",
        "Neoplasm Metastasis",
        "Lung Neoplasms",
        "Pulmonary Disease, Chronic Obstructive",
        "Heart Failure",
        "End Stage Liver Disease",
        "Kidney Failure, Chronic"
      ],
      "interventions": [
        {
          "name": "Communication Feedback Form for Patients with Serious Illness",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 817,
      "start_date": "2013-09",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2019-03-20",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 6,
      "location_summary": "Renton, Washington • Seattle, Washington",
      "locations": [
        {
          "city": "Renton",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01933789"
    },
    {
      "nct_id": "NCT01891682",
      "title": "Methionine Metabolism in Parenterally Fed Pediatric Sepsis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sepsis",
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Observational",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "1 Month to 19 Years"
      },
      "enrollment_count": 45,
      "start_date": "2012-10",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01891682"
    },
    {
      "nct_id": "NCT00202813",
      "title": "Study of the Use of Coated Venous Catheters in the Critically Ill Child",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Children in the Pediatric Intensive Care Unit or General Pediatric Care Unit Requiring a Central Venous Catheter"
      ],
      "interventions": [
        {
          "name": "Cook Spectrum Pediatric Central Venous Catheter Anti-microbial Impregnated Polyurethane and Arrow Pediatric Central Venous Catheter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Corewell Health West",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 500,
      "start_date": "2003-07",
      "completion_date": "2005-10",
      "has_results": false,
      "last_update_posted_date": "2024-04-08",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Grand Rapids, Michigan",
      "locations": [
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00202813"
    },
    {
      "nct_id": "NCT05373615",
      "title": "Cefiderocol Plasma Concentrations in Patients Receiving Renal Replacement Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pharmacokinetics"
      ],
      "interventions": [
        {
          "name": "Cefiderocol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hartford Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "120 Years",
        "sex": "ALL",
        "summary": "18 Years to 120 Years"
      },
      "enrollment_count": 14,
      "start_date": "2022-07-25",
      "completion_date": "2024-11-20",
      "has_results": false,
      "last_update_posted_date": "2024-12-18",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05373615"
    },
    {
      "nct_id": "NCT03159208",
      "title": "Prediction of Functional Outcomes From Chronic Critical Illness",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Critical Illness",
        "Prolonged Mechanical Ventilation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 589,
      "start_date": "2017-04-17",
      "completion_date": "2021-09-05",
      "has_results": false,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 6,
      "location_summary": "Denver, Colorado • The Bronx, New York • Chapel Hill, North Carolina + 3 more",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "The Bronx",
          "state": "New York"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03159208"
    },
    {
      "nct_id": "NCT04993833",
      "title": "Inter-Device Reliability of the NPi-300 Pupillometer",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Critical Illness",
        "Neuropathy"
      ],
      "interventions": [
        {
          "name": "NPi-200 and NPi-300 pupillometers",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2021-08-25",
      "completion_date": "2022-08-31",
      "has_results": false,
      "last_update_posted_date": "2022-09-30",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04993833"
    },
    {
      "nct_id": "NCT04067622",
      "title": "Novel Arm Restraint For Critically Ill Patients To Reduce Immobility, Sedation, Agitation and Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Respiratory Failure",
        "Encephalopathy",
        "ARDS",
        "Sepsis",
        "Critical Illness"
      ],
      "interventions": [
        {
          "name": "Exersides",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Vermont",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 58,
      "start_date": "2019-09-01",
      "completion_date": "2021-12-28",
      "has_results": false,
      "last_update_posted_date": "2022-03-10",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 3,
      "location_summary": "San Diego, California • Baltimore, Maryland • Burlington, Vermont",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Burlington",
          "state": "Vermont"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04067622"
    },
    {
      "nct_id": "NCT00178321",
      "title": "Improving Sleep in the Pediatric Intensive Care Unit",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill"
      ],
      "interventions": [
        {
          "name": "earplugs",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Year",
        "maximum_age": "15 Years",
        "sex": "ALL",
        "summary": "1 Year to 15 Years"
      },
      "enrollment_count": 0,
      "start_date": "2005-09",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2015-04-30",
      "last_synced_at": "2026-07-23T01:53:26.236Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00178321"
    }
  ]
}