{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=DSD%2C+Sex+Chromosome&page=3",
    "query": {
      "condition": "DSD, Sex Chromosome",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 70,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=DSD%2C+Sex+Chromosome&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=DSD%2C+Sex+Chromosome&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T00:11:37.448Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07221851",
      "title": "Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Turner Syndrome",
        "Short Stature Homeobox Gene Mutation",
        "Idiopathic Short Stature",
        "Small for Gestational Age at Delivery"
      ],
      "interventions": [
        {
          "name": "Lonapegsomatropin [SKYTROFA®]",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Somatropin Pen Injector",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Ascendis Pharma A/S",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "2 Years to 17 Years"
      },
      "enrollment_count": 186,
      "start_date": "2025-12-12",
      "completion_date": "2029-03",
      "has_results": false,
      "last_update_posted_date": "2026-09-30",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 23,
      "location_summary": "Palo Alto, California • Sacramento, California • Aurora, Colorado + 19 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Centennial",
          "state": "Colorado"
        },
        {
          "city": "Wilmington",
          "state": "Delaware"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07221851"
    },
    {
      "nct_id": "NCT00471731",
      "title": "Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Ovarian Failure, Premature",
        "Sex Chromosome Aberrations",
        "Menopause",
        "Perimenopause"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 72,
      "start_date": "2007-05-07",
      "completion_date": "2014-11-13",
      "has_results": false,
      "last_update_posted_date": "2018-02-14",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00471731"
    },
    {
      "nct_id": "NCT06740162",
      "title": "Physical Activity and Community EmPOWERment Project",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intellectual Disability",
        "Neurodevelopmental Disorders",
        "Autism Spectrum Disorder",
        "Down Syndrome",
        "Fragile X Syndrome",
        "Cri-du-Chat Syndrome",
        "De Lange Syndrome",
        "Mental Retardation, X-Linked",
        "Prader-Willi Syndrome",
        "Rubinstein-Taybi Syndrome",
        "Trisomy 13 Syndrome",
        "WAGR Syndrome",
        "Williams Syndrome"
      ],
      "interventions": [
        {
          "name": "PACE Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 376,
      "start_date": "2025-01-10",
      "completion_date": "2028-06",
      "has_results": false,
      "last_update_posted_date": "2026-02-23",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 2,
      "location_summary": "Fayetteville, Arkansas • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06740162"
    },
    {
      "nct_id": "NCT00837616",
      "title": "Estrogen Dosing in Turner Syndrome: Pharmacology and Metabolism",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Turner Syndrome",
        "Hypogonadism",
        "Premature Ovarian Failure"
      ],
      "interventions": [
        {
          "name": "17 B estradiol orally",
          "type": "DRUG"
        },
        {
          "name": "17 B estradiol",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Nemours Children's Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "20 Years",
        "sex": "FEMALE",
        "summary": "13 Years to 20 Years · Female only"
      },
      "enrollment_count": 41,
      "start_date": "2009-01",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2023-05-16",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00837616"
    },
    {
      "nct_id": "NCT02461303",
      "title": "Fertility Assessment in Patients With Klinefelter Syndrome",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Klinefelter Syndrome"
      ],
      "interventions": [
        {
          "name": "Counseling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "25 Years",
        "sex": "MALE",
        "summary": "12 Years to 25 Years · Male only"
      },
      "enrollment_count": 6,
      "start_date": "2016-01-07",
      "completion_date": "2017-12-12",
      "has_results": false,
      "last_update_posted_date": "2018-07-24",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 2,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02461303"
    },
    {
      "nct_id": "NCT06834594",
      "title": "Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Turner Syndrome",
        "Primary Ovarian Insufficiency (Poi)"
      ],
      "interventions": [
        {
          "name": "Micronized progesterone 200 MG",
          "type": "DRUG"
        },
        {
          "name": "Micronized Progesterone 100 MG",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "20 Years",
        "sex": "FEMALE",
        "summary": "12 Years to 20 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2025-07-31",
      "completion_date": "2028-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-25",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06834594"
    },
    {
      "nct_id": "NCT03185702",
      "title": "UTHealth Turner Syndrome Research Registry",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome"
      ],
      "interventions": [
        {
          "name": "Research genetic tests",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "GENETIC"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 200,
      "start_date": "2015-08-28",
      "completion_date": "2035-01-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-28",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03185702"
    },
    {
      "nct_id": "NCT00896272",
      "title": "Adaptation Among Adolescents and Adults With Klinefelter Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Klinefelter Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Human Genome Research Institute (NHGRI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": "80 Years",
        "sex": "MALE",
        "summary": "14 Years to 80 Years · Male only"
      },
      "enrollment_count": 302,
      "start_date": "2009-05-05",
      "completion_date": "2015-01-13",
      "has_results": false,
      "last_update_posted_date": "2019-12-17",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00896272"
    },
    {
      "nct_id": "NCT04948658",
      "title": "Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Turner Syndrome",
        "Post-menarcheal Adolescents",
        "Ovarian Disfunction",
        "Galactosemia",
        "Variations in Sex Characteristics",
        "Differences in Sex Development"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "2 Years to 35 Years"
      },
      "enrollment_count": 200,
      "start_date": "2021-09-13",
      "completion_date": "2030-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-05",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04948658"
    },
    {
      "nct_id": "NCT05548881",
      "title": "Implications of Maternal 45,X Mosaicism as a Secondary Genomic Finding Following Cell-Free DNA Sequencing During Pregnancy: A Deep Phenotype Study",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiovascular Phenotype",
        "Metabolic Phenotype",
        "Hypertensive Disease",
        "Psychological Phenotype",
        "Audio"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 0,
      "start_date": "2025-04-01",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-04-02",
      "last_synced_at": "2026-10-08T00:11:37.448Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05548881"
    }
  ]
}