{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Debility+Due+to+Disease",
    "query": {
      "condition": "Debility Due to Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T16:26:16.966Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04798378",
      "title": "NuroSleeve Powered Brace & Stimulation System to Restore Arm Function",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurologic Diseases",
        "Hemiparesis",
        "Quadriplegia",
        "Muscular Dystrophies",
        "Arthrogryposis",
        "Spinal Cord Injuries",
        "Charcot-Marie-Tooth",
        "Stroke",
        "Weakness of Extremities as Sequela of Stroke",
        "Weakness Due to Upper Motor Neuron Dysfunction",
        "Amyotrophic Lateral Sclerosis",
        "Spinal Muscular Atrophy",
        "Arm Paralysis",
        "Cerebral Palsy"
      ],
      "interventions": [
        {
          "name": "Neurosleeve",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "4 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2020-04-16",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-04-09",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 2,
      "location_summary": "Wilmington, Delaware • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04798378"
    },
    {
      "nct_id": "NCT03106220",
      "title": "Exercise Intervention - and Impact on Hospitalization",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sarcopenia",
        "Debility Due to Disease"
      ],
      "interventions": [
        {
          "name": "exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2017-03-01",
      "completion_date": "2021-01-14",
      "has_results": false,
      "last_update_posted_date": "2021-03-05",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 3,
      "location_summary": "Scottsdale, Arizona • Jacksonville, Florida • Rochester, Minnesota",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03106220"
    },
    {
      "nct_id": "NCT06023316",
      "title": "mGain - sEMG-based Gamified Therapy for Improved Upper Limb Rehabilitation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Upper Limb Weakness Due to Central Neurologic Injury",
        "Upper Limb Weakness Due to Peripheral Neurologic Injury",
        "Upper Limb Weakness Due to Nerve Reconstruction",
        "Upper Limb Weakness Due to Tendon Transfer Surgery",
        "Stroke",
        "Upper Limb Amputation"
      ],
      "interventions": [
        {
          "name": "mGain system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Orthocare Innovations, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2023-08-08",
      "completion_date": "2024-03-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-10",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 1,
      "location_summary": "Edmonds, Washington",
      "locations": [
        {
          "city": "Edmonds",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06023316"
    },
    {
      "nct_id": "NCT03355755",
      "title": "Exoskeleton Treatment of Deconditioning Due to Limited Ambulation Caused by Illness or Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Debility Due to Disease"
      ],
      "interventions": [
        {
          "name": "EksoGT with SmartAssist software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ekso Bionics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2017-10-11",
      "completion_date": "2018-12-13",
      "has_results": true,
      "last_update_posted_date": "2023-04-14",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 3,
      "location_summary": "Wallingford, Connecticut • Wheaton, Illinois • Omaha, Nebraska",
      "locations": [
        {
          "city": "Wallingford",
          "state": "Connecticut"
        },
        {
          "city": "Wheaton",
          "state": "Illinois"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03355755"
    },
    {
      "nct_id": "NCT05751668",
      "title": "Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel (Phase II)",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anatomic Stage IV Breast Cancer AJCC v8",
        "Chemotherapy-Induced Peripheral Neuropathy",
        "Metastatic Breast Carcinoma"
      ],
      "interventions": [
        {
          "name": "Paclitaxel",
          "type": "DRUG"
        },
        {
          "name": "Monosialotetrahexosylganglioside",
          "type": "DRUG"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Quality-of-life assessment",
          "type": "OTHER"
        },
        {
          "name": "Placebo Administration",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Alliance for Clinical Trials in Oncology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2023-11-02",
      "completion_date": "2032-03-15",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 33,
      "location_summary": "Irvine, California • Orange, California • Clearwater, Florida + 26 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Miami Beach",
          "state": "Florida"
        },
        {
          "city": "St. Petersburg",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05751668"
    },
    {
      "nct_id": "NCT05162768",
      "title": "Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mitochondrial Myopathies",
        "Mitochondrial Pathology",
        "Mitochondrial DNA Mutation",
        "Mitochondrial Diseases",
        "Mitochondrial DNA Deletion",
        "Mitochondrial DNA Depletion",
        "Mitochondrial Metabolism Defect",
        "Mitochondrial Complex I Deficiency"
      ],
      "interventions": [
        {
          "name": "Elamipretide",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stealth BioTherapeutics Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 102,
      "start_date": "2022-04-29",
      "completion_date": "2024-12-04",
      "has_results": false,
      "last_update_posted_date": "2025-10-24",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 9,
      "location_summary": "San Diego, California • Atlanta, Georgia • Boston, Massachusetts + 6 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05162768"
    },
    {
      "nct_id": "NCT06637046",
      "title": "Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Drop Foot"
      ],
      "interventions": [
        {
          "name": "Diagnostic procedures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Lidocaine HCl",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Stephen Barrett",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 20,
      "start_date": "2020-03-15",
      "completion_date": "2023-11-01",
      "has_results": false,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-07-22T16:26:16.966Z",
      "location_count": 1,
      "location_summary": "Marietta, Georgia",
      "locations": [
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06637046"
    }
  ]
}