{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Decay&page=6",
    "query": {
      "condition": "Decay",
      "page": 6
    },
    "page_size": 10
  },
  "pagination": {
    "page": 6,
    "page_size": 10,
    "total_count": 241,
    "total_pages": 25,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Decay&page=7&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Decay&page=5&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T07:18:24.952Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00066118",
      "title": "Health Effects of Silver-Mercury Dental Fillings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Caries, Dental"
      ],
      "interventions": [
        {
          "name": "Dental amalgam restorations",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "8 Years to 12 Years"
      },
      "enrollment_count": 507,
      "start_date": "1996-08",
      "completion_date": "2011-02",
      "has_results": false,
      "last_update_posted_date": "2018-06-04",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00066118"
    },
    {
      "nct_id": "NCT07419672",
      "title": "Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Negative Control Treatment Slurry (Fluoride-Free)",
          "type": "DRUG"
        },
        {
          "name": "Active Comparator Fluoride Treatment (0.454% SnF)",
          "type": "DRUG"
        },
        {
          "name": "Test Fluoride Treatment (0.454% SnF) (Investigational Toothpaste)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2024-08-12",
      "completion_date": "2024-11-21",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Noblesville, Indiana",
      "locations": [
        {
          "city": "Noblesville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07419672"
    },
    {
      "nct_id": "NCT02398695",
      "title": "Oral Alkali Production and Caries Prevention in Children (Longitudinal)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Oral Samples",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "2 Years to 7 Years"
      },
      "enrollment_count": 232,
      "start_date": "2012-10",
      "completion_date": "2015-08-27",
      "has_results": false,
      "last_update_posted_date": "2018-11-13",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02398695"
    },
    {
      "nct_id": "NCT03649659",
      "title": "Effectiveness of Silver Diamine Fluoride (SDF) in Arresting Cavitated Caries Lesions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Cavities of Teeth"
      ],
      "interventions": [
        {
          "name": "Silver Diamine Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Months",
        "maximum_age": "71 Months",
        "sex": "ALL",
        "summary": "12 Months to 71 Months"
      },
      "enrollment_count": 830,
      "start_date": "2018-10-08",
      "completion_date": "2023-04-27",
      "has_results": true,
      "last_update_posted_date": "2026-08-12",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 3,
      "location_summary": "Iowa City, Iowa • Ann Arbor, Michigan • New York, New York",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03649659"
    },
    {
      "nct_id": "NCT07100626",
      "title": "In-situ Clinical Trial Assessing Ability to Detect and Monitor Active Caries and Their Remineralization",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "BlueCheck",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Incisive Technologies Pty Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 12,
      "start_date": "2025-09-24",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-20",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07100626"
    },
    {
      "nct_id": "NCT00001726",
      "title": "Study of the Composition of Dental Plaque",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Caries",
        "Dental Plaque",
        "Periodontal Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Dental and Craniofacial Research (NIDCR)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "1998-06-19",
      "completion_date": "2009-08-03",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00001726"
    },
    {
      "nct_id": "NCT01201408",
      "title": "DPBRN Longitudinal Study of Dental Restorations Placed on Previously Un-restored Surfaces",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dental Practice-Based Research Network",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Years and older"
      },
      "enrollment_count": 9291,
      "start_date": "2007-11",
      "completion_date": "2011-09",
      "has_results": false,
      "last_update_posted_date": "2011-09-20",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 6,
      "location_summary": "Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01201408"
    },
    {
      "nct_id": "NCT00504452",
      "title": "Safety and Efficacy Study of KP-1461 to Treat ART-Experienced HIV+ Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "KP-1461",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Koronis Pharmaceuticals.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 27,
      "start_date": "2007-07",
      "completion_date": "2009-06",
      "has_results": false,
      "last_update_posted_date": "2011-11-07",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 30,
      "location_summary": "Little Rock, Arkansas • Long Beach, California • Los Angeles, California + 25 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00504452"
    },
    {
      "nct_id": "NCT03576326",
      "title": "BEhavioral EConomics for Oral Health iNnovation Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Toothbrushing",
        "Dental Plaque",
        "Parent-Child Relations",
        "Oral Hygiene",
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Drawing Incentive",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "47 Months",
        "sex": "ALL",
        "summary": "6 Months to 47 Months"
      },
      "enrollment_count": 244,
      "start_date": "2018-05-09",
      "completion_date": "2021-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-09-19",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Santa Monica, California",
      "locations": [
        {
          "city": "Santa Monica",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03576326"
    },
    {
      "nct_id": "NCT03294590",
      "title": "Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries, Dental",
        "Health Behavior"
      ],
      "interventions": [
        {
          "name": "OHT Parent targeted text messages",
          "type": "OTHER"
        },
        {
          "name": "CWT Parent targeted text messages",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "0 Months",
        "maximum_age": "7 Years",
        "sex": "ALL",
        "summary": "0 Months to 7 Years"
      },
      "enrollment_count": 754,
      "start_date": "2018-03-09",
      "completion_date": "2022-02-28",
      "has_results": true,
      "last_update_posted_date": "2023-10-24",
      "last_synced_at": "2026-10-21T07:18:24.952Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03294590"
    }
  ]
}