{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Disc+Disease%28DDD%29&page=2",
    "query": {
      "condition": "Degenerative Disc Disease(DDD)",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Disc+Disease%28DDD%29&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T09:41:23.035Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01028300",
      "title": "Clinical Outcomes of Lumbar Degenerative Disc Disease in Active-Duty U.S. Service Personnel",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "ProDisc™-L Total Disc Replacement (TDR)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Synthes USA HQ, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 4,
      "start_date": "2010-04",
      "completion_date": "2011-03",
      "has_results": true,
      "last_update_posted_date": "2016-03-02",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01028300"
    },
    {
      "nct_id": "NCT00437190",
      "title": "Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Radiculopathy",
        "Myelopathy",
        "Cervical Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "ATLANTIS™ Cervical Plate System and allograft",
          "type": "DEVICE"
        },
        {
          "name": "BRYAN Cervical Disc Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Spinal and Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 494,
      "start_date": "2003-06",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-05-13",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 38,
      "location_summary": "Phoenix, Arizona • Little Rock, Arkansas • Campbell, California + 31 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Campbell",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00437190"
    },
    {
      "nct_id": "NCT05489822",
      "title": "PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease (DDD)",
        "Instabilities",
        "Trauma",
        "Deformity"
      ],
      "interventions": [
        {
          "name": "VERTICALE® Cervical System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Silony Medical GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2023-01-13",
      "completion_date": "2024-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05489822"
    },
    {
      "nct_id": "NCT00798902",
      "title": "Pilot Study to Assess Safety/Preliminary Effectiveness of Prefix in Subjects With Degenerative Disc Disease (DDD) Undergoing Spine Fusion Surgery",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "Prefix (AMPLEX) B2A Peptide Enhanced Ceramic Granules",
          "type": "DEVICE"
        },
        {
          "name": "Iliac crest autograft",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "BioSurface Engineering Technologies, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 22,
      "start_date": "2008-11",
      "completion_date": "2012-10",
      "has_results": false,
      "last_update_posted_date": "2012-03-09",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 6,
      "location_summary": "Durango, Colorado • Washington D.C., District of Columbia • Kansas City, Kansas + 3 more",
      "locations": [
        {
          "city": "Durango",
          "state": "Colorado"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Jefferson City",
          "state": "Missouri"
        },
        {
          "city": "Johnson City",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00798902"
    },
    {
      "nct_id": "NCT06011551",
      "title": "HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease (DDD)"
      ],
      "interventions": [
        {
          "name": "The ReGelTec HYDRAFIL™ System",
          "type": "DEVICE"
        },
        {
          "name": "Conservative Care Management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "ReGelTec, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "22 Years to 85 Years"
      },
      "enrollment_count": 225,
      "start_date": "2025-01-13",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 13,
      "location_summary": "Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 10 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Greenwood Village",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06011551"
    },
    {
      "nct_id": "NCT00878579",
      "title": "Percutaneous Dynamic Stabilization (PDS) System Versus Fusion for Treating Degenerative Disc Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "PDS System",
          "type": "DEVICE"
        },
        {
          "name": "Fusion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Interventional Spine, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2009-03",
      "completion_date": "2013-02",
      "has_results": false,
      "last_update_posted_date": "2013-02-21",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 2,
      "location_summary": "Cincinnati, Ohio • Willow Grove, Pennsylvania",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Willow Grove",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00878579"
    },
    {
      "nct_id": "NCT00432159",
      "title": "Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Cervical TDR",
          "type": "DEVICE"
        },
        {
          "name": "ACDF with plate",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DePuy Spine",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "21 Years to 70 Years"
      },
      "enrollment_count": 500,
      "start_date": "2006-07-01",
      "completion_date": "2016-05-01",
      "has_results": true,
      "last_update_posted_date": "2017-10-20",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 30,
      "location_summary": "Beverly Hills, California • Sacramento, California • Loveland, Colorado + 26 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00432159"
    },
    {
      "nct_id": "NCT00775801",
      "title": "Freedom Lumbar Disc in the Treatment of Lumbar Degenerative Disc Disease",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease (DDD)"
      ],
      "interventions": [
        {
          "name": "FLD",
          "type": "DEVICE"
        },
        {
          "name": "Control",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "AxioMed Spine Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 300,
      "start_date": "2008-09",
      "completion_date": "2018-07",
      "has_results": false,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 12,
      "location_summary": "Los Angeles, California • San Diego, California • Loveland, Colorado + 9 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Loveland",
          "state": "Colorado"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00775801"
    },
    {
      "nct_id": "NCT00637156",
      "title": "Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent Levels",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervical Degenerative Disc Disease",
        "Radiculopathy",
        "Myelopathy"
      ],
      "interventions": [
        {
          "name": "PRESTIGE LP device at two adjacent levels",
          "type": "DEVICE"
        },
        {
          "name": "Bi-level fusion with ATLANTIS Cervical Plate System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Spinal and Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 397,
      "start_date": "2006-06",
      "completion_date": "2018-02-01",
      "has_results": true,
      "last_update_posted_date": "2018-05-01",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 29,
      "location_summary": "Huntsville, Alabama • Beverly Hills, California • Colton, California + 26 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Colton",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00637156"
    },
    {
      "nct_id": "NCT01198470",
      "title": "TRIUMPH Lumbar Artificial Disc IDE: A Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "TRIUMPH® Lumbar Artificial Disc",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Globus Medical Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2010-09",
      "completion_date": "2016-12",
      "has_results": true,
      "last_update_posted_date": "2018-10-02",
      "last_synced_at": "2026-07-24T09:41:23.035Z",
      "location_count": 1,
      "location_summary": "Savannah, Georgia",
      "locations": [
        {
          "city": "Savannah",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01198470"
    }
  ]
}