{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Disc+Disease%2C+Spondylolisthesis&page=2",
    "query": {
      "condition": "Degenerative Disc Disease, Spondylolisthesis",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 73,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Disc+Disease%2C+Spondylolisthesis&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Disc+Disease%2C+Spondylolisthesis&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T06:04:07.696Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04566874",
      "title": "SPIRA™-A 3D and HCT/p DBM vs. Medtronic Divergent™-L/Perimeter™ and Recombinant BMP-2",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylolisthesis",
        "Scoliosis"
      ],
      "interventions": [
        {
          "name": "ALIF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Camber Spine Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-07-13",
      "completion_date": "2021-07",
      "has_results": false,
      "last_update_posted_date": "2020-09-28",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Plano, Texas",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04566874"
    },
    {
      "nct_id": "NCT03077204",
      "title": "BIO4 Clinical Case Study: Cervical Spine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Trauma (Including Fractures)",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window).",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Aviator Anterior Cervical Plating System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DEVICE"
      ],
      "sponsor": "Seton Healthcare Family",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2017-04-06",
      "completion_date": "2020-01-30",
      "has_results": true,
      "last_update_posted_date": "2022-01-14",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 1,
      "location_summary": "Austin, Texas",
      "locations": [
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03077204"
    },
    {
      "nct_id": "NCT00762723",
      "title": "Clinical Outcomes of the Trinica(R) Anterior Lumbar Plate: Fixed Screws vs. Variable Screws",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "Trinica Anterior Lumbar Plate System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 19,
      "start_date": "2008-02",
      "completion_date": "2012-09",
      "has_results": true,
      "last_update_posted_date": "2014-04-17",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 3,
      "location_summary": "Daphne, Alabama • Mobile, Alabama • San Bernardino, California",
      "locations": [
        {
          "city": "Daphne",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "San Bernardino",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00762723"
    },
    {
      "nct_id": "NCT04615260",
      "title": "Rate of Bony Fusion Using NanoBone® Synthetic Bone Graft Versus Local Autologous Bone Graft.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "NanoBone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Artoss Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-07-19",
      "completion_date": "2025-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-12",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04615260"
    },
    {
      "nct_id": "NCT03647501",
      "title": "Lumbar Fusion With Nexxt Spine 3D-Printed Titanium Interbody Cages",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease",
        "Lumbar Spinal Stenosis",
        "Lumbar Spondylolisthesis",
        "Lumbar Spinal Deformity",
        "Lumbar Spondylosis"
      ],
      "interventions": [
        {
          "name": "Interbody cage (titanium)",
          "type": "DEVICE"
        },
        {
          "name": "Interbody cage (PEEK)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 53,
      "start_date": "2018-08-22",
      "completion_date": "2022-03-16",
      "has_results": true,
      "last_update_posted_date": "2023-06-15",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03647501"
    },
    {
      "nct_id": "NCT01944345",
      "title": "Patient Registry to Observe Outcomes Following Implantation of the VariLift Interbody Fusion Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prolapsed Lumbar Disc",
        "Prolapsed Cervical Disc",
        "Intervertebral Disc Degeneration",
        "Spondylolisthesis, Grade 1",
        "Intervertebral Disc Displacement"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Wenzel Spine",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 69,
      "start_date": "2013-06",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2016-05-17",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • San Antonio, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01944345"
    },
    {
      "nct_id": "NCT05029726",
      "title": "Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Lumbar Spinal Stenosis",
        "Lumbar Disc Herniation",
        "Lumbar Spondylolisthesis",
        "Lumbar Spondylosis",
        "Lumbar Radiculopathy",
        "Lumbar Spine Instability",
        "Synovial Cyst",
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Degenerative Intervertebral Discs"
      ],
      "interventions": [
        {
          "name": "Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine",
          "type": "DRUG"
        },
        {
          "name": "normal saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "John O'Toole",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 125,
      "start_date": "2022-02-01",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05029726"
    },
    {
      "nct_id": "NCT00000409",
      "title": "Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Spondylolisthesis",
        "Spinal Stenosis",
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Decompressive laminectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-surgical treatments",
          "type": "OTHER"
        },
        {
          "name": "Fusion--Instrumented",
          "type": "PROCEDURE"
        },
        {
          "name": "Fusion-Non-instrumented",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Dartmouth-Hitchcock Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 304,
      "start_date": "2000-03",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-08-04",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 13,
      "location_summary": "Oakland, California • San Francisco, California • Decatur, Georgia + 9 more",
      "locations": [
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Decatur",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Scarborough",
          "state": "Maine"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00000409"
    },
    {
      "nct_id": "NCT05023733",
      "title": "Clinical and Radiographic Outcomes of TLIF w/3D Printed Cellular Implant",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Foraminal Stenosis",
        "Degenerative Disc Disease",
        "Lumbar Spondylolisthesis",
        "Lumbar Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "CONDUIT™ Interbody Platform composed of the EIT (Emerging Implant Technologies) Cellular Titanium®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Farhan Karim",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "35 Years to 80 Years"
      },
      "enrollment_count": 150,
      "start_date": "2021-10-01",
      "completion_date": "2025-10-01",
      "has_results": false,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 1,
      "location_summary": "Hartford, Connecticut",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05023733"
    },
    {
      "nct_id": "NCT02626624",
      "title": "Safety and Efficacy of the CarboClear Pedicle Screw System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spondylolisthesis, Grade 1"
      ],
      "interventions": [
        {
          "name": "Implantation of the CarboClear Pedicle Screw System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CarboFix Orthopedics Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "72 Years",
        "sex": "ALL",
        "summary": "21 Years to 72 Years"
      },
      "enrollment_count": 57,
      "start_date": "2015-12-27",
      "completion_date": "2022-12-28",
      "has_results": true,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-10-06T06:04:07.696Z",
      "location_count": 5,
      "location_summary": "Boston, Massachusetts • Rochester, Minnesota • Brooklyn, New York + 2 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        },
        {
          "city": "Akron",
          "state": "Ohio"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02626624"
    }
  ]
}