{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Intervertebral+Discs&page=2",
    "query": {
      "condition": "Degenerative Intervertebral Discs",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Intervertebral+Discs&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T09:48:02.084Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05489822",
      "title": "PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease (DDD)",
        "Instabilities",
        "Trauma",
        "Deformity"
      ],
      "interventions": [
        {
          "name": "VERTICALE® Cervical System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Silony Medical GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2023-01-13",
      "completion_date": "2024-11-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-11",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05489822"
    },
    {
      "nct_id": "NCT01633034",
      "title": "Tissue Collection for Understanding Intervertebral Disc Degeneration and Back Pain",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intervertebral Disc Degeneration",
        "Back Pain"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2011-01",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2024-03-20",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 2,
      "location_summary": "Manhasset, New York • Manhattan, New York",
      "locations": [
        {
          "city": "Manhasset",
          "state": "New York"
        },
        {
          "city": "Manhattan",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01633034"
    },
    {
      "nct_id": "NCT00316121",
      "title": "Safety and Efficacy Study of Healos as a Bone Replacement to Treat Degenerative Disc Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "HEALOS and Leopard Cage",
          "type": "DEVICE"
        },
        {
          "name": "Leopard Cage and Autograft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Advanced Technologies and Regenerative Medicine, LLC (ATRM)",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 138,
      "start_date": "2006-04",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2011-03-03",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 17,
      "location_summary": "Little Rock, Arkansas • Beverly Hills, California • Brandon, Florida + 14 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "Brandon",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Savannah",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00316121"
    },
    {
      "nct_id": "NCT04208048",
      "title": "FLXfitTM 15 TLIF Interbody Fusion Device",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "FLXfit 15TM device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 31,
      "start_date": "2018-10-15",
      "completion_date": "2022-08-22",
      "has_results": false,
      "last_update_posted_date": "2023-03-14",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04208048"
    },
    {
      "nct_id": "NCT05037968",
      "title": "MagnetOs Flex Matrix Compared to Trinity Elite Mixed With Local Autograft in Patients Undergoing up to Four-level Instrumented Posterolateral Fusion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spine Fusion",
        "Leg Pain and/or Back Pain"
      ],
      "interventions": [
        {
          "name": "MagnetOs Flex Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Trinity Elite",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kuros Biosurgery AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2024-06-10",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-25",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 7,
      "location_summary": "Hartford, Connecticut • Columbia, Maryland • Bloomfield Hills, Michigan + 4 more",
      "locations": [
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Columbia",
          "state": "Maryland"
        },
        {
          "city": "Bloomfield Hills",
          "state": "Michigan"
        },
        {
          "city": "Pinehurst",
          "state": "North Carolina"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05037968"
    },
    {
      "nct_id": "NCT00758758",
      "title": "Performance of the Hedrocel(R) Cervical Fusion Device",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Symptomatic Cervical Disc Disease"
      ],
      "interventions": [
        {
          "name": "Anterior Cervical Discectomy and Fusion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 231,
      "start_date": "2001-12",
      "completion_date": "2009-06",
      "has_results": true,
      "last_update_posted_date": "2013-08-23",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 13,
      "location_summary": "Los Angeles, California • Clearwater, Florida • Orlando, Florida + 9 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Louisville",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00758758"
    },
    {
      "nct_id": "NCT04566874",
      "title": "SPIRA™-A 3D and HCT/p DBM vs. Medtronic Divergent™-L/Perimeter™ and Recombinant BMP-2",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylolisthesis",
        "Scoliosis"
      ],
      "interventions": [
        {
          "name": "ALIF",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Camber Spine Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "22 Years to 75 Years"
      },
      "enrollment_count": 100,
      "start_date": "2020-07-13",
      "completion_date": "2021-07",
      "has_results": false,
      "last_update_posted_date": "2020-09-28",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • Plano, Texas",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04566874"
    },
    {
      "nct_id": "NCT00810212",
      "title": "Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "PLF with autograft",
          "type": "PROCEDURE"
        },
        {
          "name": "PLF with NeoFuse",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "Mesoblast, Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-11",
      "completion_date": "2011-11",
      "has_results": false,
      "last_update_posted_date": "2020-06-02",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 1,
      "location_summary": "Plano, Texas",
      "locations": [
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810212"
    },
    {
      "nct_id": "NCT01549366",
      "title": "Comparison of the Aspen Device Versus Pedicle Screws for Supplemental Posterior Fixation in Lumbar Interbody Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degeneration of Lumbar Intervertebral Disc"
      ],
      "interventions": [
        {
          "name": "Aspen Spinous Process Fixation Device",
          "type": "DEVICE"
        },
        {
          "name": "Pedicle Screws",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 64,
      "start_date": "2012-02",
      "completion_date": "2016-01",
      "has_results": false,
      "last_update_posted_date": "2018-03-07",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 3,
      "location_summary": "Paducah, Kentucky • Lockport, New York • Medford, Oregon",
      "locations": [
        {
          "city": "Paducah",
          "state": "Kentucky"
        },
        {
          "city": "Lockport",
          "state": "New York"
        },
        {
          "city": "Medford",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01549366"
    },
    {
      "nct_id": "NCT03513445",
      "title": "Peri-Incisional Drug Injection in Lumbar Spine Surgery",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lumbar Disc Herniation",
        "Degenerative Disc Disease",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "Morphine",
          "type": "DRUG"
        },
        {
          "name": "Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "naropin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-06-01",
      "completion_date": "2022-09",
      "has_results": false,
      "last_update_posted_date": "2022-08-19",
      "last_synced_at": "2026-05-22T09:48:02.084Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03513445"
    }
  ]
}