{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Lumbar+Disc+Disease&page=2",
    "query": {
      "condition": "Degenerative Lumbar Disc Disease",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Lumbar+Disc+Disease&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T18:12:40.510Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01771471",
      "title": "A Study Comparing the Safety and Effectiveness of Cartilage Cell Injected Into the Lumbar Disc as Compared to a Placebo",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "NuQu",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "ISTO Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2012-11",
      "completion_date": "2020-09",
      "has_results": false,
      "last_update_posted_date": "2017-08-31",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 10,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Santa Monica, California + 7 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Santa Monica",
          "state": "California"
        },
        {
          "city": "Macon",
          "state": "Georgia"
        },
        {
          "city": "Newton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01771471"
    },
    {
      "nct_id": "NCT01415908",
      "title": "INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Lumbar Spine Degeneration"
      ],
      "interventions": [
        {
          "name": "INFUSE Bone Graft",
          "type": "DEVICE"
        },
        {
          "name": "Iliac Crest Bone Graft",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Medtronic Spinal and Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2011-07",
      "completion_date": "2015-01",
      "has_results": true,
      "last_update_posted_date": "2016-02-18",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 5,
      "location_summary": "Mesa, Arizona • Los Angeles, California • Gulf Breeze, Florida + 2 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Gulf Breeze",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01415908"
    },
    {
      "nct_id": "NCT03327272",
      "title": "Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Stenosis",
        "Herniated Nucleus Pulposus",
        "Degenerative Disc Disease",
        "Spondylosis",
        "Myelopathy",
        "Radiculopathy",
        "Myeloradiculopathy"
      ],
      "interventions": [
        {
          "name": "Methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Rush University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 0,
      "start_date": "2018-05-22",
      "completion_date": "2020-07-24",
      "has_results": false,
      "last_update_posted_date": "2020-11-20",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03327272"
    },
    {
      "nct_id": "NCT02070484",
      "title": "Human Amniotic Tissue-derived Allograft, NuCel, in Posteriolateral Lumbar Fusions for Degenerative Disc Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylolisthesis",
        "Spondylosis",
        "Intervertebral Disk Displacement",
        "Intervertebral Disk Degeneration",
        "Spinal Diseases",
        "Bone Diseases",
        "Musculoskeletal Diseases",
        "Spondylolysis"
      ],
      "interventions": [
        {
          "name": "NuCel",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Demineralized Bone Matrix",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "OhioHealth",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 6,
      "start_date": "2014-02",
      "completion_date": "2017-03-24",
      "has_results": true,
      "last_update_posted_date": "2018-09-28",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 2,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02070484"
    },
    {
      "nct_id": "NCT04679844",
      "title": "Post Marketing Study of MagnetOs Easypack Putty Standalone Compared to Demineralized Bone Matrix or Fibers Mixed With Autograft in Patients Undergoing Posterolateral Lumbar Fusion",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spine Fusion",
        "Back Pain"
      ],
      "interventions": [
        {
          "name": "MagnetOs Easypack Putty",
          "type": "DEVICE"
        },
        {
          "name": "Demineralized Bone Matrix or Fibers mixed with local autograft bone",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Kuros Biosurgery AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-12-06",
      "completion_date": "2027-08-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-20",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 6,
      "location_summary": "Irvine, California • Grand Rapids, Michigan • St Louis, Missouri + 3 more",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Grand Rapids",
          "state": "Michigan"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04679844"
    },
    {
      "nct_id": "NCT04418830",
      "title": "Lumbar Interbody Implant Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Degenerative Scoliosis",
        "Spinal Stenosis",
        "Sagittal Deformity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NuVasive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1050,
      "start_date": "2020-10-01",
      "completion_date": "2026-07-01",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 16,
      "location_summary": "La Jolla, California • Los Alamitos, California • Merced, California + 13 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Los Alamitos",
          "state": "California"
        },
        {
          "city": "Merced",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04418830"
    },
    {
      "nct_id": "NCT00679107",
      "title": "A Prospective Pilot Study of the OP-1 Putty in Uninstrumented Posterolateral Fusions",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Lumbar Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "Use of OP-1 Putty in Uninstrumented posterolateral fusion",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Olympus Biotech Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "81 Years",
        "sex": "ALL",
        "summary": "18 Years to 81 Years"
      },
      "enrollment_count": 48,
      "start_date": "1999-06",
      "completion_date": "2005-07",
      "has_results": false,
      "last_update_posted_date": "2011-06-10",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 5,
      "location_summary": "New Haven, Connecticut • Chicago, Illinois • Royal Oak, Michigan + 2 more",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Royal Oak",
          "state": "Michigan"
        },
        {
          "city": "Akron",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00679107"
    },
    {
      "nct_id": "NCT02272140",
      "title": "Advanced XLIF Monitoring Multicenter Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Lumbar Disc Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "NuVasive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 324,
      "start_date": "2014-07-09",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 12,
      "location_summary": "La Jolla, California • Tampa, Florida • Atlanta, Georgia + 8 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02272140"
    },
    {
      "nct_id": "NCT00810212",
      "title": "Safety and Efficacy Study of NeoFuse in Subjects Requiring Posterolateral Lumbar Fusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "PLF with autograft",
          "type": "PROCEDURE"
        },
        {
          "name": "PLF with NeoFuse",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "Mesoblast, Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 0,
      "start_date": "2008-11",
      "completion_date": "2011-11",
      "has_results": false,
      "last_update_posted_date": "2020-06-02",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 1,
      "location_summary": "Plano, Texas",
      "locations": [
        {
          "city": "Plano",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00810212"
    },
    {
      "nct_id": "NCT01850771",
      "title": "Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Radiculopathy",
        "Herniated Disc",
        "Disc Degeneration"
      ],
      "interventions": [
        {
          "name": "Regenexx PL-Disc",
          "type": "PROCEDURE"
        },
        {
          "name": "Steroid Epidural",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Regenexx, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 8,
      "start_date": "2013-05",
      "completion_date": "2016-05",
      "has_results": false,
      "last_update_posted_date": "2016-06-03",
      "last_synced_at": "2026-06-10T18:12:40.510Z",
      "location_count": 1,
      "location_summary": "Broomfield, Colorado",
      "locations": [
        {
          "city": "Broomfield",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01850771"
    }
  ]
}