{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Spinal+Conditions", "query": { "condition": "Degenerative Spinal Conditions" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 145, "total_pages": 15, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Spinal+Conditions&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-07-24T09:50:12.189Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01850771", "title": "Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Radiculopathy", "Herniated Disc", "Disc Degeneration" ], "interventions": [ { "name": "Regenexx PL-Disc", "type": "PROCEDURE" }, { "name": "Steroid Epidural", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Regenexx, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 8, "start_date": "2013-05", "completion_date": "2016-05", "has_results": false, "last_update_posted_date": "2016-06-03", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Broomfield, Colorado", "locations": [ { "city": "Broomfield", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT01850771" }, { "nct_id": "NCT03487367", "title": "Clinical Trial Readiness for SCA1 and SCA3", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Spinocerebellar Ataxia Type 1", "Spinocerebellar Ataxia 3" ], "interventions": [], "intervention_types": [], "sponsor": "The Methodist Hospital Research Institute", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 200, "start_date": "2018-08-16", "completion_date": "2023-12-31", "has_results": false, "last_update_posted_date": "2022-01-19", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Houston, Texas", "locations": [ { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03487367" }, { "nct_id": "NCT03711058", "title": "Study of PI3Kinase Inhibition (Copanlisib) and Anti-PD-1 Antibody Nivolumab in Relapsed/Refractory Solid Tumors With Expansions in Mismatch-repair Proficient (MSS) Colorectal Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Unresectable or Metastatic Microsatellite Stable (MSS) Solid Tumor", "Microsatellite Stable (MSS) Colon Cancer" ], "interventions": [ { "name": "Copanlisib", "type": "DRUG" }, { "name": "Nivolumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 48, "start_date": "2019-01-17", "completion_date": "2025-06-30", "has_results": true, "last_update_posted_date": "2025-09-16", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03711058" }, { "nct_id": "NCT00034242", "title": "High-Dose Intravenous Immunoglobulin to Treat Cerebellar Degeneration", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Spinocerebellar Degenerations" ], "interventions": [ { "name": "high-dose intravenous immunoglobulin (IVIG)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 20, "start_date": "2002-04", "completion_date": "2004-02", "has_results": false, "last_update_posted_date": "2008-03-04", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Bethesda, Maryland", "locations": [ { "city": "Bethesda", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00034242" }, { "nct_id": "NCT05444751", "title": "GA + ESP vs. SA + ESP in Lumbar Decompression Surgeries", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Lumbar Disc Herniation", "Lumbar Disc Disease", "Lumbar Radiculopathy" ], "interventions": [ { "name": "General anesthetic", "type": "DRUG" }, { "name": "SA + ESP", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hospital for Special Surgery, New York", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 142, "start_date": "2022-03-22", "completion_date": "2026-09", "has_results": false, "last_update_posted_date": "2026-04-28", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT05444751" }, { "nct_id": "NCT05029726", "title": "Regional Anesthesia in Minimally Invasive Lumbar Spine Surgery", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Lumbar Spinal Stenosis", "Lumbar Disc Herniation", "Lumbar Spondylolisthesis", "Lumbar Spondylosis", "Lumbar Radiculopathy", "Lumbar Spine Instability", "Synovial Cyst", "Degenerative Disc Disease", "Degenerative Spondylolisthesis", "Degenerative Intervertebral Discs" ], "interventions": [ { "name": "Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine", "type": "DRUG" }, { "name": "normal saline", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "John O'Toole", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 125, "start_date": "2022-02-01", "completion_date": "2027-04-30", "has_results": false, "last_update_posted_date": "2026-02-17", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT05029726" }, { "nct_id": "NCT02994719", "title": "Gait Analysis in Neurological Disease", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Parkinson's Disease", "Parkinsonian Disorders", "Atypical Parkinson Disease", "Progressive Supranuclear Palsy", "Multiple System Atrophy", "Corticobasal Degeneration", "Gait, Frontal", "Huntington Disease", "Ataxia, Spinocerebellar" ], "interventions": [ { "name": "Anti-Parkinson medication", "type": "DRUG" }, { "name": "Deep Brain Stimulation", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 120, "start_date": "2016-03-01", "completion_date": "2027-07-07", "has_results": false, "last_update_posted_date": "2026-07-08", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02994719" }, { "nct_id": "NCT06415136", "title": "Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Degenerative Disc Disease", "Disc Herniation" ], "interventions": [ { "name": "SeaSpine Shoreline", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Research Source", "sponsor_class": "NETWORK", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 40, "start_date": "2023-05-05", "completion_date": "2027-05", "has_results": false, "last_update_posted_date": "2025-08-22", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Southfield, Michigan", "locations": [ { "city": "Southfield", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT06415136" }, { "nct_id": "NCT05701059", "title": "Comparison of Artificial Disc Implants in Cervical Disc Arthroplasty", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cervical Spondylosis With Myelopathy", "Cervical Radiculopathy", "Cervical Disc Herniation", "Degenerative Disc Disease" ], "interventions": [ { "name": "Cervical arthroplasty", "type": "PROCEDURE" }, { "name": "Semi-Constrained Nuvasive Simplify", "type": "DEVICE" }, { "name": "Unconstrained Biomet Zimmer Mobi-C", "type": "DEVICE" } ], "intervention_types": [ "PROCEDURE", "DEVICE" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 20, "start_date": "2023-05-01", "completion_date": "2026-12-01", "has_results": false, "last_update_posted_date": "2026-02-13", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05701059" }, { "nct_id": "NCT02365922", "title": "Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "FTLD", "Progressive Supranuclear Palsy (PSP)", "Frontotemporal Dementia (FTD)", "Corticobasal Degeneration (CBD)", "PPA Syndrome", "Behavioral Variant Frontotemporal Dementia (bvFTD)", "Semantic Variant Primary Progressive Aphasia (svPPA)", "Nonfluent Variant Primary Progressive Aphasia (nfvPPA)", "FTD With Amyotrophic Lateral Sclerosis (FTD/ALS)", "Amyotrophic Lateral Sclerosis (ALS)", "Oligosymptomatic PSP (oPSP)", "Corticobasal Syndrome (CBS)" ], "interventions": [], "intervention_types": [], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 1489, "start_date": "2014-09", "completion_date": "2020-09", "has_results": false, "last_update_posted_date": "2021-05-21", "last_synced_at": "2026-07-24T09:50:12.189Z", "location_count": 15, "location_summary": "Birmingham, Alabama • Los Angeles, California • San Diego, California + 12 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02365922" } ] }