{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Spine+Disease&page=5",
    "query": {
      "condition": "Degenerative Spine Disease",
      "page": 5
    },
    "page_size": 10
  },
  "pagination": {
    "page": 5,
    "page_size": 10,
    "total_count": 299,
    "total_pages": 30,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Spine+Disease&page=6&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+Spine+Disease&page=4&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-14T03:18:45.431Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04007094",
      "title": "Single-Armed Use of ViviGen Cellular Bone Matrix in Patients Undergoing Posterolateral Lumbar Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Degenerative Disc Disease",
        "Spinal Stenosis",
        "Spondylosis",
        "Spondylolisthesis"
      ],
      "interventions": [
        {
          "name": "ViviGen Cellular Bone Matrix",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2019-02-12",
      "completion_date": "2022-01-21",
      "has_results": true,
      "last_update_posted_date": "2024-01-24",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04007094"
    },
    {
      "nct_id": "NCT06447194",
      "title": "Effect of RECK in Posterior Spinal Fusion",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Degenerative Lumbar Spinal Stenosis",
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Degenerative Disease"
      ],
      "interventions": [
        {
          "name": "Ropivacaine, Epinephrine, Clonidine, and Ketorolac Injection Cocktail",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "88 Years",
        "sex": "ALL",
        "summary": "18 Years to 88 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-10-01",
      "completion_date": "2027-04-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-31",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06447194"
    },
    {
      "nct_id": "NCT03425682",
      "title": "ViBone in Cervical and Lumbar Spine Fusion",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spondylosis",
        "Cervical Spondylosis",
        "Spondylolisthesis",
        "Herniated Nucleus Pulposus",
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "ViBone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Elutia Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 118,
      "start_date": "2018-05-14",
      "completion_date": "2021-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-03-04",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 4,
      "location_summary": "San Diego, California • Danbury, Connecticut • Annapolis, Maryland + 1 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Danbury",
          "state": "Connecticut"
        },
        {
          "city": "Annapolis",
          "state": "Maryland"
        },
        {
          "city": "Austin",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03425682"
    },
    {
      "nct_id": "NCT04770571",
      "title": "Posterior Cervical Fixation Study",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease",
        "Craniocervical Injuries",
        "Cervical Radiculopathy",
        "Cervical Disc Disease",
        "Cervical Fusion",
        "Cervical Spine Disease",
        "Cervical Myelopathy",
        "Cervical Instabilities Spine",
        "Thoracic Injury"
      ],
      "interventions": [
        {
          "name": "observational study",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "NuVasive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2022-05-10",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2025-12-22",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 7,
      "location_summary": "Orange, California • Hartford, Connecticut • Hyattsville, Maryland + 4 more",
      "locations": [
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Hyattsville",
          "state": "Maryland"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04770571"
    },
    {
      "nct_id": "NCT04439032",
      "title": "Artoss Prospective Spine Registry Outcomes",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Spinal Fusion"
      ],
      "interventions": [
        {
          "name": "NanoBone Bone Graft Substitute",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Artoss Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 330,
      "start_date": "2020-08-03",
      "completion_date": "2025-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-02-12",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 6,
      "location_summary": "Chandler, Arizona • Tempe, Arizona • San Diego, California + 3 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04439032"
    },
    {
      "nct_id": "NCT01714804",
      "title": "Efficacy and Safety of Integra Accell Evo3 DBM in Instrumented Lumbar Spine Fusion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stenosis",
        "Spondylosis",
        "Degenerative Changes"
      ],
      "interventions": [
        {
          "name": "Accell Evo3 Prospective Use",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SeaSpine, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-08",
      "completion_date": "2016-10",
      "has_results": true,
      "last_update_posted_date": "2018-01-23",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 1,
      "location_summary": "Durango, Colorado",
      "locations": [
        {
          "city": "Durango",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01714804"
    },
    {
      "nct_id": "NCT02347410",
      "title": "Spineology Clinical Outcomes Trial: An IDE Investigation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lumbar Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "SIFS graft containment device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Spineology, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 102,
      "start_date": "2015-01-22",
      "completion_date": "2020-03-04",
      "has_results": true,
      "last_update_posted_date": "2021-10-20",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 10,
      "location_summary": "DeLand, Florida • Shreveport, Louisiana • Thibodaux, Louisiana + 7 more",
      "locations": [
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Shreveport",
          "state": "Louisiana"
        },
        {
          "city": "Thibodaux",
          "state": "Louisiana"
        },
        {
          "city": "Clinton",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02347410"
    },
    {
      "nct_id": "NCT03898232",
      "title": "Fibergraft Interbody Fusion Retrospective",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative Disc Disease",
        "Degenerative Spondylolisthesis",
        "Spinal Degeneration",
        "Spinal Stenosis"
      ],
      "interventions": [
        {
          "name": "Computed Tomography (CT) Scan of the Lumbar Spine",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "RADIATION"
      ],
      "sponsor": "Bone and Joint Clinic of Baton Rouge",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2019-05-09",
      "completion_date": "2020-02-20",
      "has_results": false,
      "last_update_posted_date": "2021-01-29",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 1,
      "location_summary": "Baton Rouge, Louisiana",
      "locations": [
        {
          "city": "Baton Rouge",
          "state": "Louisiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03898232"
    },
    {
      "nct_id": "NCT03461458",
      "title": "Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Degenerative Disc Disease"
      ],
      "interventions": [
        {
          "name": "Autologous Adipose-Derived Mesenchymal Stromal Cells",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2018-10-17",
      "completion_date": "2021-02-06",
      "has_results": false,
      "last_update_posted_date": "2022-01-25",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03461458"
    },
    {
      "nct_id": "NCT00310440",
      "title": "An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intervertebral Disk Degeneration"
      ],
      "interventions": [
        {
          "name": "P-15 Synthetic osteoconductive bone substitute",
          "type": "DEVICE"
        },
        {
          "name": "Autologous bone",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "CeraPedics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 319,
      "start_date": "2006-01",
      "completion_date": "2019-05-23",
      "has_results": true,
      "last_update_posted_date": "2020-03-12",
      "last_synced_at": "2026-10-14T03:18:45.431Z",
      "location_count": 10,
      "location_summary": "San Francisco, California • Thornton, Colorado • Sarasota, Florida + 6 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Thornton",
          "state": "Colorado"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00310440"
    }
  ]
}