{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Degenerative+and+Traumatic+Pathology+of+the+Knee",
    "query": {
      "condition": "Degenerative and Traumatic Pathology of the Knee"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T08:16:14.444Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01191151",
      "title": "Web Based Orthopaedic Sports Medicine Registry",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Degenerative and Traumatic Pathology of the Knee",
        "Degenerative and Traumatic Pathology of the Shoulder and Elbow",
        "Degenerative and Traumatic Pathology of the Foot and Ankle",
        "Degenerative and Traumatic Pathology of the Hand and Wrist",
        "Degenerative and Traumatic Pathology of the Hip"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Arthrex, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 12500,
      "start_date": "2010-09",
      "completion_date": "2023-07-30",
      "has_results": false,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-05-22T08:16:14.444Z",
      "location_count": 220,
      "location_summary": "Birmingham, Alabama • Montgomery, Alabama • Anchorage, Alaska + 171 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01191151"
    },
    {
      "nct_id": "NCT03034811",
      "title": "Persona Partial Knee Clinical Outcomes Study",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Avascular Necrosis",
        "Traumatic Arthritis",
        "Conditional Tibial Condyle or Plateau Fractures",
        "Conditional Revision of the Articular Surface"
      ],
      "interventions": [
        {
          "name": "Persona Partial Knee system",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 757,
      "start_date": "2017-02-08",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-22",
      "last_synced_at": "2026-05-22T08:16:14.444Z",
      "location_count": 9,
      "location_summary": "Fremont, California • Golden, Colorado • Chicago, Illinois + 6 more",
      "locations": [
        {
          "city": "Fremont",
          "state": "California"
        },
        {
          "city": "Golden",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "New Castle",
          "state": "Indiana"
        },
        {
          "city": "Beverly",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03034811"
    },
    {
      "nct_id": "NCT03048201",
      "title": "Physica System Total Knee Replacement Registry Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Traumatic Arthritis",
        "Avascular Necrosis",
        "Degenerative Joint Disease of Knee",
        "Rheumatoid Arthritis",
        "Deformity of Knee"
      ],
      "interventions": [
        {
          "name": "Physica Kinematic Retaining Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Physica Cruciate Retaining Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Physica Posterior Stabilized Knee System",
          "type": "DEVICE"
        },
        {
          "name": "Physica Cruciate Retaining Knee System with LMC Liner",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Limacorporate S.p.a",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 800,
      "start_date": "2017-03-24",
      "completion_date": "2030-03",
      "has_results": false,
      "last_update_posted_date": "2023-03-21",
      "last_synced_at": "2026-05-22T08:16:14.444Z",
      "location_count": 5,
      "location_summary": "Rancho Mirage, California • Daytona Beach, Florida • Aurora, Illinois + 2 more",
      "locations": [
        {
          "city": "Rancho Mirage",
          "state": "California"
        },
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "Aurora",
          "state": "Illinois"
        },
        {
          "city": "Syracuse",
          "state": "New York"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03048201"
    },
    {
      "nct_id": "NCT00854295",
      "title": "Prospective Multicenter Post Approval Study of the LPS-Flex Mobile Bearing Knee",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis",
        "Traumatic Arthritis",
        "Avascular Necrosis of the Femoral Condyle",
        "Moderate Varus",
        "Valgus",
        "Flexion Deformities"
      ],
      "interventions": [
        {
          "name": "NexGen LPS-Flex Mobile Bearing Knee",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Zimmer Biomet",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 266,
      "start_date": "2009-04",
      "completion_date": "2021-06",
      "has_results": true,
      "last_update_posted_date": "2023-02-14",
      "last_synced_at": "2026-05-22T08:16:14.444Z",
      "location_count": 3,
      "location_summary": "Tamarac, Florida • Auburn Hills, Michigan • Knoxville, Tennessee",
      "locations": [
        {
          "city": "Tamarac",
          "state": "Florida"
        },
        {
          "city": "Auburn Hills",
          "state": "Michigan"
        },
        {
          "city": "Knoxville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00854295"
    }
  ]
}