{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dementia+Prevention",
    "query": {
      "condition": "Dementia Prevention"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 98,
    "total_pages": 10,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dementia+Prevention&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-10T20:34:20.390Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07392723",
      "title": "ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cognitive Dysfunction",
        "Alzheimer Disease",
        "Blood-Brain Barrier",
        "Apolipoprotein E, Deficiency or Defect of",
        "Brain Aging",
        "Fatty Acids, Omega-3"
      ],
      "interventions": [
        {
          "name": "Alpha-Linolenic Acid (2.6 g/day)",
          "type": "DRUG"
        },
        {
          "name": "Placebo Control Group",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Michal Schnaider Beeri, Ph.D.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2025-01-12",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 1,
      "location_summary": "New Brunswick, New Jersey",
      "locations": [
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07392723"
    },
    {
      "nct_id": "NCT03961386",
      "title": "FallsTalk Falls Prevention Program for Caregivers and Persons With Memory Loss or Dementia",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Falls (Accidents) in Old Age"
      ],
      "interventions": [
        {
          "name": "FallsTalk-C",
          "type": "BEHAVIORAL"
        },
        {
          "name": "FallsTalk",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brookside Research & Development Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2019-03-13",
      "completion_date": "2020-05",
      "has_results": false,
      "last_update_posted_date": "2019-06-06",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 1,
      "location_summary": "Freeland, Washington",
      "locations": [
        {
          "city": "Freeland",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03961386"
    },
    {
      "nct_id": "NCT00040378",
      "title": "Prevention of Alzheimer's Disease by Vitamin E and Selenium (PREADVISE)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "alphatocopherol",
          "type": "DRUG"
        },
        {
          "name": "Selenium",
          "type": "DRUG"
        },
        {
          "name": "Placebo replacement for vitamin E",
          "type": "DRUG"
        },
        {
          "name": "Placebo replacement for Selenium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Frederick Schmitt",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "90 Years",
        "sex": "MALE",
        "summary": "60 Years to 90 Years · Male only"
      },
      "enrollment_count": 4246,
      "start_date": "2002-05",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2018-03-14",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 84,
      "location_summary": "Birmingham, Alabama • Anchorage, Alaska • Chula Vista, California + 70 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Anchorage",
          "state": "Alaska"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Glendale",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00040378"
    },
    {
      "nct_id": "NCT03537261",
      "title": "CPI Training for Parents of Children With ASD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Autism Spectrum Disorder"
      ],
      "interventions": [
        {
          "name": "Parent-based Crisis Prevention Institute (CPI) physical management training program (P-CPI)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 81,
      "start_date": "2018-08-08",
      "completion_date": "2020-06-15",
      "has_results": true,
      "last_update_posted_date": "2021-06-29",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 1,
      "location_summary": "Lexington, Massachusetts",
      "locations": [
        {
          "city": "Lexington",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03537261"
    },
    {
      "nct_id": "NCT03718494",
      "title": "Continuation of The Kronos Early Estrogen Prevention Study (KEEPS)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Alzheimer Dementia"
      ],
      "interventions": [
        {
          "name": "Brain Magnetic Resonance Imaging (MRI)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "F-18 Florbetapir Positron Emission Tomography (PET) Imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "F-18 AV-1451 Positron Emission Tomography (PET) Imaging",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Neuropsychological Testing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "49 Years",
        "maximum_age": "72 Years",
        "sex": "FEMALE",
        "summary": "49 Years to 72 Years · Female only"
      },
      "enrollment_count": 299,
      "start_date": "2019-05-22",
      "completion_date": "2022-09-01",
      "has_results": false,
      "last_update_posted_date": "2023-07-17",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 6,
      "location_summary": "Phoenix, Arizona • San Francisco, California • New Haven, Connecticut + 3 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03718494"
    },
    {
      "nct_id": "NCT06033066",
      "title": "Financial Incentives and Recruitment to the APT Webstudy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alzheimer Disease",
        "Dementia",
        "Preclinical Alzheimer's Disease",
        "Prodromal Alzheimer's Disease"
      ],
      "interventions": [
        {
          "name": "Financial Incentives",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Message",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 44844,
      "start_date": "2024-03-01",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 1,
      "location_summary": "Martinez, California",
      "locations": [
        {
          "city": "Martinez",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06033066"
    },
    {
      "nct_id": "NCT00007189",
      "title": "Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Alzheimer Disease"
      ],
      "interventions": [
        {
          "name": "Naproxen Sodium (Aleve)",
          "type": "DRUG"
        },
        {
          "name": "Celecoxib (Celebrex)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Seattle Institute for Biomedical and Clinical Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 2625,
      "start_date": "2001-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-10-19",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 6,
      "location_summary": "Sun City, Arizona • Tampa, Florida • Baltimore, Maryland + 3 more",
      "locations": [
        {
          "city": "Sun City",
          "state": "Arizona"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00007189"
    },
    {
      "nct_id": "NCT06042413",
      "title": "Prediction and Prevention of Postoperative Mortality and Morbidity",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Postoperative Delirium (POD)",
        "Postoperative Neurocognitive Disorder",
        "Major Adverse Cardiac and Cerebrovascular Events",
        "Perioperative Complications",
        "Postoperative Cognitive Decline"
      ],
      "interventions": [
        {
          "name": "Personalized CPC Prehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Meditation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Daily Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Social Support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Proactive Bundle Interventions",
          "type": "OTHER"
        },
        {
          "name": "Pre-operative Standard of Care",
          "type": "PROCEDURE"
        },
        {
          "name": "Intra-operative Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL",
        "PROCEDURE"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1200,
      "start_date": "2026-06",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 5,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06042413"
    },
    {
      "nct_id": "NCT02765048",
      "title": "Violence Prevention for Adolescent Girls With Prior Maltreatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD",
        "Depression",
        "Aggression",
        "Victimization"
      ],
      "interventions": [
        {
          "name": "GAIN Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 312,
      "start_date": "2010-08",
      "completion_date": "2014-08",
      "has_results": false,
      "last_update_posted_date": "2016-05-06",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 3,
      "location_summary": "Arnold, Missouri • St Louis, Missouri",
      "locations": [
        {
          "city": "Arnold",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02765048"
    },
    {
      "nct_id": "NCT06647498",
      "title": "A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Alzheimers Disease",
        "Dementia",
        "Alzheimers Disease, Familial"
      ],
      "interventions": [
        {
          "name": "Remternetug",
          "type": "DRUG"
        },
        {
          "name": "Matching Placebo (Remternetug)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 280,
      "start_date": "2024-11-22",
      "completion_date": "2034-08",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-06-10T20:34:20.390Z",
      "location_count": 12,
      "location_summary": "Birmingham, Alabama • La Jolla, California • New Haven, Connecticut + 9 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Park Ridge",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06647498"
    }
  ]
}