{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dementia+Syndromes&page=8", "query": { "condition": "Dementia Syndromes", "page": 8 }, "page_size": 10 }, "pagination": { "page": 8, "page_size": 10, "total_count": 172, "total_pages": 18, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dementia+Syndromes&page=9&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dementia+Syndromes&page=7&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-10T18:47:40.996Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02759887", "title": "Relationship Between Down Syndrome (DS) and Alzheimer's Disease (AD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Down Syndrome", "Alzheimer's Dementia" ], "interventions": [ { "name": "biospecimen collection", "type": "PROCEDURE" }, { "name": "cognitive assessments", "type": "OTHER" }, { "name": "caregiver questionnaire", "type": "OTHER" }, { "name": "Florbetapir F18 imaging", "type": "PROCEDURE" }, { "name": "MRI", "type": "PROCEDURE" }, { "name": "Fludeoxyglucose F18 (FDG)", "type": "PROCEDURE" }, { "name": "Tau Pet", "type": "PROCEDURE" }, { "name": "Actigraphy", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "St. Joseph's Hospital and Medical Center, Phoenix", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "ALL", "summary": "21 Years and older" }, "enrollment_count": 19, "start_date": "2016-11", "completion_date": "2018-12", "has_results": false, "last_update_posted_date": "2019-10-29", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "Phoenix, Arizona", "locations": [ { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02759887" }, { "nct_id": "NCT02141971", "title": "Down Syndrome Biomarker Initiative (DSBI)", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Down Syndrome", "Alzheimer's Disease" ], "interventions": [], "intervention_types": [], "sponsor": "Michael Rafii", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "30 Years to 60 Years" }, "enrollment_count": 12, "start_date": "2013-06-01", "completion_date": "2017-04-15", "has_results": false, "last_update_posted_date": "2017-05-02", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02141971" }, { "nct_id": "NCT02699190", "title": "LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Leukodystrophy", "White Matter Disease", "4H Syndrome", "Adrenoleukodystrophy", "AMN", "ALD", "ALD (Adrenoleukodystrophy)", "X-linked Adrenoleukodystrophy", "X-ALD", "Adrenomyeloneuropathy", "Aicardi Goutieres Syndrome", "AGS", "Alexander Disease", "Alexanders Leukodystrophy", "AxD", "ADLD", "Canavan Disease", "CTX", "Cerebrotendinous Xanthomatoses", "Krabbe Disease", "GALC Deficiency", "Globoid Leukodystrophy", "TUBB4A-Related Leukodystrophy", "H-ABC - Hypomyelination, Atrophy of Basal Ganglia and Cerebellum", "HBSL", "HBSL - Hypomyelination, Brain Stem, Spinal Cord, Leg Spasticity", "LBSL", "Leukoencephalopathy With Brain Stem and Spinal Cord Involvement and High Lactate Syndrome (Disorder)", "Leukoencephalopathy With Brainstem and Spinal Cord Involvement and Lactate Elevation", "ALSP", "CSF1R Gene Mutation", "HCC - Hypomyelination and Congenital Cataract", "MLC1", "Megalencephalic Leukoencephalopathy With Subcortical Cysts 1", "MLD", "Metachromatic Leukodystrophy", "PMD", "Pelizaeus-Merzbacher Disease", "PLP1 Null Syndrome", "PLP1 Gene Duplication | Blood or Tissue | Mutations", "Pelizaeus-Merzbacher-Like Disease, 1", "Peroxisomal Biogenesis Disorder", "Zellweger Syndrome", "Refsum Disease", "Salla Disease", "Sialic Storage Disease", "Sjögren", "Sjogren-Larsson Syndrome", "Van Der Knapp Disease", "Vanishing White Matter Disease", "Charcot-Marie-Tooth", "CMT", "Mct8 (Slc16A2)-Specific Thyroid Hormone Cell Transporter Deficiency", "Allan-Herndon-Dudley Syndrome", "Cadasil", "Cockayne Syndrome", "Multiple Sulfatase Deficiency", "Gangliosidoses", "GM2 Gangliosidosis", "BPAN", "Labrune Syndrome", "LCC", "Mucopolysaccharidoses", "TBCK-Related Intellectual Disability Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "Children's Hospital of Philadelphia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "18 Years", "sex": "ALL", "summary": "Up to 18 Years" }, "enrollment_count": 236, "start_date": "2017-01-06", "completion_date": "2024-10-31", "has_results": true, "last_update_posted_date": "2025-11-10", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT02699190" }, { "nct_id": "NCT04141891", "title": "Advancing Understanding of Transportation Options", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Diabetic Retinopathy", "Macular Degeneration", "Glaucoma", "Retinitis Pigmentosa", "Vision Disorders", "Acute Coronary Syndrome", "Implantable Defibrillator User", "Congestive Heart Failure", "Hypertrophic Obstructive Cardiomyopathy", "Orthostatic Hypotension", "Syncope", "Presyncope", "Narcolepsy", "Dementia", "Multiple Sclerosis", "Parkinson Disease", "Brain Injuries", "Spinal Cord Injuries", "Stroke", "Vertigo", "Dizziness", "Seizures", "Substance Use", "Insulin Dependent Diabetes Mellitus", "Arthritis", "Foot--Abnormalities", "Chronic Obstructive Pulmonary Disease", "Obstructive Sleep Apnea", "End Stage Renal Disease", "Sleep Apnea", "Insomnia", "Restless Legs Syndrome" ], "interventions": [ { "name": "Driving Decision Aid", "type": "BEHAVIORAL" }, { "name": "Older Drivers Website", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 529, "start_date": "2019-12-12", "completion_date": "2023-12-21", "has_results": true, "last_update_posted_date": "2025-02-21", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 3, "location_summary": "La Jolla, California • Aurora, Colorado • Indianapolis, Indiana", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT04141891" }, { "nct_id": "NCT05027113", "title": "App-Based Mindfulness Meditation for People of Color Who Experience Race-Related Stress", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Stress, Psychological", "Anxiety", "Depression", "Rumination", "Emotional Regulation", "Mindfulness", "Self-Compassion", "Emotional Distress" ], "interventions": [ { "name": "Mindfulness meditation", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 155, "start_date": "2021-10-13", "completion_date": "2022-12-02", "has_results": false, "last_update_posted_date": "2023-05-25", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05027113" }, { "nct_id": "NCT05336344", "title": "Supporting Family Caregivers of Persons With Dementia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Caregiver Stress Syndrome", "Anxiety", "Depression" ], "interventions": [ { "name": "ENCODE", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 452, "start_date": "2022-07-15", "completion_date": "2026-04-10", "has_results": false, "last_update_posted_date": "2026-08-24", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "Philadelphia, Pennsylvania", "locations": [ { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT05336344" }, { "nct_id": "NCT02531360", "title": "Evaluation of [18F]MNI-815 as a Potential PET Radioligand for Imaging Tau Protein in the Brain of Patients With Tauopathies", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Alzheimer's Disease (AD)", "Progressive Supranuclear Palsy (PSP)", "Cortical Basal Syndrome (CBS)", "Frontal Temporal Dementia (FTD)" ], "interventions": [ { "name": "[18F]MNI-815 (MNI-815)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Molecular NeuroImaging", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "50 Years", "maximum_age": "90 Years", "sex": "ALL", "summary": "50 Years to 90 Years" }, "enrollment_count": 7, "start_date": "2015-05", "completion_date": "2016-08", "has_results": false, "last_update_posted_date": "2016-12-16", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT02531360" }, { "nct_id": "NCT04149197", "title": "Down Syndrome Clinical Trials - Study of Alzheimer's Disease in Down Syndrome", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer's Disease in Down Syndrome" ], "interventions": [], "intervention_types": [], "sponsor": "LuMind IDSC Foundation", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "25 Years", "maximum_age": null, "sex": "ALL", "summary": "25 Years and older" }, "enrollment_count": 252, "start_date": "2019-06-30", "completion_date": "2024-04-17", "has_results": false, "last_update_posted_date": "2024-06-27", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 14, "location_summary": "Phoenix, Arizona • Irvine, California • La Jolla, California + 11 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Irvine", "state": "California" }, { "city": "La Jolla", "state": "California" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT04149197" }, { "nct_id": "NCT03233646", "title": "Retinal Imaging in Neurodegenerative Disease", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Alzheimer's Disease", "Mild Cognitive Impairment", "Parkinson's Disease", "Multiple Sclerosis", "Huntington Disease", "Lewy Body Dementia", "Frontotemporal Dementia", "Amyotrophic Lateral Sclerosis (ALS)", "APOE-4 Positive", "Traumatic Brain Injury", "Concussion", "Post-Traumatic Stress Disorder", "Down Syndrome", "Neuro-Degenerative Disease", "Normal Cognition" ], "interventions": [ { "name": "Retinal and Choroidal Imaging", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2000, "start_date": "2017-07-20", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-02-04", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT03233646" }, { "nct_id": "NCT01056965", "title": "Davunetide (AL-108) in Predicted Tauopathies - Pilot Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Predicted Tauopathies, Including", "Progressive Supranuclear Palsy", "Frontotemporal Dementia With Parkinsonism Linked to Chromosome 17", "Corticobasal Degeneration Syndrome", "Progressive Nonfluent Aphasia" ], "interventions": [ { "name": "davunetide (AL-108, NAP)", "type": "DRUG" }, { "name": "Placebo nasal spray", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "40 Years to 85 Years" }, "enrollment_count": 12, "start_date": "2010-01", "completion_date": "2012-12", "has_results": false, "last_update_posted_date": "2019-04-05", "last_synced_at": "2026-10-10T18:47:40.996Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01056965" } ] }