{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Demodex+Blepharitis",
    "query": {
      "condition": "Demodex Blepharitis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 8,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T14:30:34.737Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07400965",
      "title": "Evaluation of the Safety and Efficacy of GLK-321 in Subjects With Demodex Blepharitis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Demodex Blepharitis"
      ],
      "interventions": [
        {
          "name": "GLK-321 low dose BID",
          "type": "DRUG"
        },
        {
          "name": "GLK-321 mid dose BID",
          "type": "DRUG"
        },
        {
          "name": "GLK-321 high dose BID",
          "type": "DRUG"
        },
        {
          "name": "GLK-321 high dose QD",
          "type": "DRUG"
        },
        {
          "name": "Placebo BID",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Glaukos Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2025-12-05",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07400965"
    },
    {
      "nct_id": "NCT05454956",
      "title": "Pilot Study Comparing the Safety and Efficacy of Two Dosing Regimens of TP-03 for the Treatment of MGD",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Blepharitis",
        "Demodex Infestation"
      ],
      "interventions": [
        {
          "name": "TP-03",
          "type": "DRUG"
        },
        {
          "name": "TP-03 Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tarsus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2022-08-03",
      "completion_date": "2023-05-18",
      "has_results": true,
      "last_update_posted_date": "2025-10-01",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 5,
      "location_summary": "Northridge, California • Kansas City, Missouri • Cary, North Carolina + 2 more",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Cary",
          "state": "North Carolina"
        },
        {
          "city": "Shelby",
          "state": "North Carolina"
        },
        {
          "city": "New Freedom",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05454956"
    },
    {
      "nct_id": "NCT06795165",
      "title": "Study of the Safety and Efficacy of Moxidectin Tablets for the Reduction of Demodex Eyelash Infestation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Blepharitis"
      ],
      "interventions": [
        {
          "name": "Moxidectin 2 MG Oral Tablet",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eye Research Foundation, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2025-02-02",
      "completion_date": "2025-06-15",
      "has_results": false,
      "last_update_posted_date": "2025-08-12",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 1,
      "location_summary": "Newport Beach, California",
      "locations": [
        {
          "city": "Newport Beach",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06795165"
    },
    {
      "nct_id": "NCT06054217",
      "title": "Effect of an Exploratory Vehicle on Meibomian Gland Dysfunction in Patients With Demodex",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Meibomian Gland Dysfunction",
        "Demodex Infestation of Eyelid",
        "Blepharitis",
        "Demodectic Blepharitis"
      ],
      "interventions": [
        {
          "name": "Vehicle of TP-03",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tarsus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2023-08-01",
      "completion_date": "2024-06-15",
      "has_results": false,
      "last_update_posted_date": "2024-04-09",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 2,
      "location_summary": "Northridge, California • Shelby, North Carolina",
      "locations": [
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "Shelby",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06054217"
    },
    {
      "nct_id": "NCT04784091",
      "title": "Trial to Evaluate the Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Blepharitis"
      ],
      "interventions": [
        {
          "name": "TP-03",
          "type": "DRUG"
        },
        {
          "name": "TP-03 Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tarsus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 412,
      "start_date": "2021-04-29",
      "completion_date": "2022-05-09",
      "has_results": true,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 21,
      "location_summary": "Scottsdale, Arizona • Northridge, California • San Ramon, California + 18 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Northridge",
          "state": "California"
        },
        {
          "city": "San Ramon",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04784091"
    },
    {
      "nct_id": "NCT06182358",
      "title": "Impact of XDEMVY® on Demodex Blepharitis in Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Demodex Blepharitis"
      ],
      "interventions": [
        {
          "name": "Lotilaner ophthalmic solution, 0.25%",
          "type": "DRUG"
        },
        {
          "name": "Vehicle control",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tarsus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 145,
      "start_date": "2023-12-27",
      "completion_date": "2025-01-27",
      "has_results": false,
      "last_update_posted_date": "2025-07-02",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 14,
      "location_summary": "Cave Creek, Arizona • Long Beach, California • Colorado Springs, Colorado + 11 more",
      "locations": [
        {
          "city": "Cave Creek",
          "state": "Arizona"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06182358"
    },
    {
      "nct_id": "NCT04475432",
      "title": "Safety and Efficacy of TP-03 for the Treatment of Demodex Blepharitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Blepharitis"
      ],
      "interventions": [
        {
          "name": "TP-03, 0.25%",
          "type": "DRUG"
        },
        {
          "name": "TP-03 Vehicle",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tarsus Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 421,
      "start_date": "2020-09-09",
      "completion_date": "2021-05-04",
      "has_results": true,
      "last_update_posted_date": "2023-12-21",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 15,
      "location_summary": "Phoenix, Arizona • Newport Beach, California • Colorado Springs, Colorado + 11 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Newport Beach",
          "state": "California"
        },
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Carmel",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04475432"
    },
    {
      "nct_id": "NCT01647217",
      "title": "Demodex Blepharitis Treatment Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Blepharitis"
      ],
      "interventions": [
        {
          "name": "Terpinen-4-ol",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "BioTissue Holdings, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "15 Years to 80 Years"
      },
      "enrollment_count": 17,
      "start_date": "2014-02",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2017-07-26",
      "last_synced_at": "2026-07-22T14:30:34.737Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01647217"
    }
  ]
}