{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Anaesthesia&page=2",
    "query": {
      "condition": "Dental Anaesthesia",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Anaesthesia&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T11:20:05.593Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00309322",
      "title": "Study of NV-101 for Safety and Efficacy in Pediatric Dental Patients Undergoing Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anesthesia, Dental"
      ],
      "interventions": [
        {
          "name": "Phentolamine Mesylate (NV-101)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novalar Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "4 Years to 11 Years"
      },
      "enrollment_count": 150,
      "start_date": "2006-03",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2006-11-17",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00309322"
    },
    {
      "nct_id": "NCT01302483",
      "title": "Safety and Effectiveness of Kovacaine Nasal Spray for Dental Anesthesia",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Anesthesia Efficacy"
      ],
      "interventions": [
        {
          "name": "3% tetracaine HCL with 0.05% oxymetazoline HCL",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Renatus, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2008-12",
      "completion_date": "2009-01",
      "has_results": true,
      "last_update_posted_date": "2015-06-17",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01302483"
    },
    {
      "nct_id": "NCT06757075",
      "title": "Management of Postoperative Discomfort in Young Children Following Dental Rehabilitation Under General Anesthesia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Ibuprofen",
          "type": "DRUG"
        },
        {
          "name": "Acetominophen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "4 Years to 6 Years"
      },
      "enrollment_count": 75,
      "start_date": "2025-04-16",
      "completion_date": "2027-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Brighton, Massachusetts",
      "locations": [
        {
          "city": "Brighton",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06757075"
    },
    {
      "nct_id": "NCT00309335",
      "title": "Study of NV-101 for Efficacy, Pharmacodynamics, and Safety in Dental Patients Undergoing Maxillary Procedures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia, Dental"
      ],
      "interventions": [
        {
          "name": "Phentolamine Mesylate (NV-101)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Novalar Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 240,
      "start_date": "2006-02",
      "completion_date": "2006-07",
      "has_results": false,
      "last_update_posted_date": "2006-11-17",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00309335"
    },
    {
      "nct_id": "NCT03318952",
      "title": "Articaine vs Lidocaine for Pediatric Dental Procedures",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anesthesia, Dental",
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "lidocaine",
          "type": "DRUG"
        },
        {
          "name": "articaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "4 Years to 14 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-09",
      "completion_date": "2023-06",
      "has_results": false,
      "last_update_posted_date": "2022-11-03",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03318952"
    },
    {
      "nct_id": "NCT01479517",
      "title": "Open-Label Study of Efficacy and Recommended Dose of Kovacaine Mist for Anesthetizing Maxillary Teeth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Kovacaine Mist 0.1 mL x 4 sprays",
          "type": "DRUG"
        },
        {
          "name": "Kovacaine Mist 0.2 mL x 2 sprays",
          "type": "DRUG"
        },
        {
          "name": "Kovacaine Mist 0.2 mL x 1 spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Renatus, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-01",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2016-12-29",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Colorado Springs, Colorado",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01479517"
    },
    {
      "nct_id": "NCT05964387",
      "title": "Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Molar Incisor Hypomineralization",
        "Anesthesia, Local"
      ],
      "interventions": [
        {
          "name": "SDF",
          "type": "DEVICE"
        },
        {
          "name": "Placebo",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "6 Years to 11 Years"
      },
      "enrollment_count": 50,
      "start_date": "2023-06-12",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05964387"
    },
    {
      "nct_id": "NCT04787731",
      "title": "Efficacy of Two Local Anesthetics on Quality of Life After Endodontic Treatment",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Local Anesthetic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU College of Dentistry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 100,
      "start_date": "2019-07-29",
      "completion_date": "2024-10-01",
      "has_results": false,
      "last_update_posted_date": "2023-11-08",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04787731"
    },
    {
      "nct_id": "NCT01701505",
      "title": "Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "400uL of Kovacaine Mist",
          "type": "DRUG"
        },
        {
          "name": "200uL of Kovacaine Mist",
          "type": "DRUG"
        },
        {
          "name": "120uL of Kovacaine Mist",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Renatus, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "3 Years to 17 Years"
      },
      "enrollment_count": 48,
      "start_date": "2012-10",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2017-08-30",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Fort Collins, Colorado",
      "locations": [
        {
          "city": "Fort Collins",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01701505"
    },
    {
      "nct_id": "NCT01574807",
      "title": "The Anesthetic Efficacy of 3% Mepivacaine Plus 2% Lidocaine With 1:100,000 Epinephrine for Lower Jaw Dental Injections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "mepivacaine + lidocaine followed by lidocaine +lidocaine",
          "type": "DRUG"
        },
        {
          "name": "lidocaine + lidocaine followed by mepivacaine + lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ohio State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "2012-05",
      "completion_date": "2013-05",
      "has_results": true,
      "last_update_posted_date": "2020-11-17",
      "last_synced_at": "2026-07-24T11:20:05.593Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01574807"
    }
  ]
}