{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Anesthesia+Efficacy",
    "query": {
      "condition": "Dental Anesthesia Efficacy"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 135,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Anesthesia+Efficacy&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T16:42:13.314Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01479517",
      "title": "Open-Label Study of Efficacy and Recommended Dose of Kovacaine Mist for Anesthetizing Maxillary Teeth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Kovacaine Mist 0.1 mL x 4 sprays",
          "type": "DRUG"
        },
        {
          "name": "Kovacaine Mist 0.2 mL x 2 sprays",
          "type": "DRUG"
        },
        {
          "name": "Kovacaine Mist 0.2 mL x 1 spray",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "St. Renatus, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-01",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2016-12-29",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Colorado Springs, Colorado",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01479517"
    },
    {
      "nct_id": "NCT01127438",
      "title": "A Dose-ranging Study to Evaluate the Safety and Efficacy of LUSEDRA (Fospropofol Disodium) as an Intravenous Sedative for Diagnostic or Therapeutic Colonoscopy in Adult Special Populations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sedation"
      ],
      "interventions": [
        {
          "name": "fospropofol disodium Subgroup 1 Lower Dose",
          "type": "DRUG"
        },
        {
          "name": "fospropofol disodium Subgroup 1 Approved Dose",
          "type": "DRUG"
        },
        {
          "name": "fospropofol disodium Subgroup 2 Lower Dose",
          "type": "DRUG"
        },
        {
          "name": "fospropofol disodium Subgroup 2 Approved Dose",
          "type": "DRUG"
        },
        {
          "name": "fospropofol disodium Subgroup 3 Lower Dose",
          "type": "DRUG"
        },
        {
          "name": "fospropofol disodium Subgroup 3 Approved Dose",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eisai Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 153,
      "start_date": "2010-04",
      "completion_date": "2011-06",
      "has_results": true,
      "last_update_posted_date": "2013-02-08",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 23,
      "location_summary": "Phoenix, Arizona • Baldwin Park, California • San Diego, California + 20 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Baldwin Park",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01127438"
    },
    {
      "nct_id": "NCT02379221",
      "title": "Efficacy of Injected Local Anesthetic vs Topical Anesthetic in Cosmetic Injectable Fillers.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Injectable",
          "type": "DRUG"
        },
        {
          "name": "Topical",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "David Grant U.S. Air Force Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 49,
      "start_date": "2014-09",
      "completion_date": "2016-04",
      "has_results": true,
      "last_update_posted_date": "2020-04-29",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Travis Air Force Base, California",
      "locations": [
        {
          "city": "Travis Air Force Base",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02379221"
    },
    {
      "nct_id": "NCT03653988",
      "title": "Comparison of Pre-op and Post-op Pectoralis Nerve Block",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Postoperative Pain",
        "Anesthesia",
        "Nerve Block"
      ],
      "interventions": [
        {
          "name": "PEC I/II blocks by anesthesiologist - pre-operative",
          "type": "PROCEDURE"
        },
        {
          "name": "PEC I/II blocks by surgeon - intra-operative",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Melinda Seering",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 80 Years · Female only"
      },
      "enrollment_count": 34,
      "start_date": "2019-03-12",
      "completion_date": "2021-10-31",
      "has_results": true,
      "last_update_posted_date": "2024-08-16",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03653988"
    },
    {
      "nct_id": "NCT02773537",
      "title": "Motor-Sparing Peripheral Nerve Blockade Facilitates Mobility Post Total Knee Arthroplasty: A Randomized Controlled Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Arthroplasty, Replacement, Knee"
      ],
      "interventions": [
        {
          "name": "Femoral nerve catheter and sciatic nerve block",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal catheter and selective tibial block",
          "type": "DRUG"
        },
        {
          "name": "Adductor canal catheter only",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2015-10",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2019-03-27",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02773537"
    },
    {
      "nct_id": "NCT00846690",
      "title": "Comparative Efficacy of 20% Benzocaine Versus TAC Alternate Gel",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dental Pain",
        "Postoperative Pain"
      ],
      "interventions": [
        {
          "name": "benzocaine",
          "type": "DRUG"
        },
        {
          "name": "TAC alternate gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 20,
      "start_date": "2009-01",
      "completion_date": "2009-05",
      "has_results": false,
      "last_update_posted_date": "2009-02-19",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "6655 Travis Suite 460, Texas",
      "locations": [
        {
          "city": "6655 Travis Suite 460",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00846690"
    },
    {
      "nct_id": "NCT03303794",
      "title": "0.25% Bupivacaine Versus a Mixture of 0.25% Bupivacaine and 1.3 % Liposomal Bupivacaine in Patients Undergoing Tka",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "Exparel",
          "type": "DRUG"
        },
        {
          "name": "0.25% bupivacaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "40 Years to 80 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-10-25",
      "completion_date": "2018-06-27",
      "has_results": true,
      "last_update_posted_date": "2020-03-20",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03303794"
    },
    {
      "nct_id": "NCT02717728",
      "title": "Effectiveness of Fascia Iliaca Nerve Block for Post Hip Arthroscopy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hip Surgery Corrective",
        "Anesthesia; Functional"
      ],
      "interventions": [
        {
          "name": "Drug group Fascia iliaca nerve block",
          "type": "PROCEDURE"
        },
        {
          "name": "Control group sham nerve block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "12 Years to 35 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-12",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02717728"
    },
    {
      "nct_id": "NCT03276026",
      "title": "A Study to Compare Neostigmine vs Sugammadex in Length of PACU Stay in Patients Undergoing Sleeve Gastrectomy Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Postoperative Nausea and Vomiting",
        "Respiratory Conditions Due to Other External Agents"
      ],
      "interventions": [
        {
          "name": "Sugammadex",
          "type": "DRUG"
        },
        {
          "name": "Neostigmine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Virtua Health, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 68,
      "start_date": "2018-02-12",
      "completion_date": "2018-11-08",
      "has_results": true,
      "last_update_posted_date": "2019-05-28",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "Mount Holly, New Jersey",
      "locations": [
        {
          "city": "Mount Holly",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03276026"
    },
    {
      "nct_id": "NCT01309581",
      "title": "Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depression",
        "Bipolar Depression"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Methohexital",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James Murrough",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 3,
      "start_date": "2010-04",
      "completion_date": "2010-10",
      "has_results": true,
      "last_update_posted_date": "2013-08-30",
      "last_synced_at": "2026-06-26T16:42:13.314Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01309581"
    }
  ]
}