{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Decay&page=4",
    "query": {
      "condition": "Dental Decay",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 209,
    "total_pages": 21,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Decay&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Decay&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-11T09:59:04.825Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01796106",
      "title": "Clinical Trial Proximal Caries Infiltration and Detection",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries,Dental"
      ],
      "interventions": [
        {
          "name": "Resin infiltration",
          "type": "DEVICE"
        },
        {
          "name": "Fluoride varnish & Oral hygiene instruction",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "DMG Dental Material Gesellschaft mbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "13 Years",
        "sex": "ALL",
        "summary": "6 Years to 13 Years"
      },
      "enrollment_count": 12,
      "start_date": "2015-03",
      "completion_date": "2016-03",
      "has_results": true,
      "last_update_posted_date": "2023-07-19",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01796106"
    },
    {
      "nct_id": "NCT00385008",
      "title": "TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Migraine Disorders"
      ],
      "interventions": [
        {
          "name": "Combination Product (sumatriptan succinate / naproxen sodium)",
          "type": "DRUG"
        },
        {
          "name": "RELPAX(eletriptan) 40mg Tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 20,
      "start_date": "2006-09-13",
      "completion_date": "2006-11-24",
      "has_results": true,
      "last_update_posted_date": "2018-02-12",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00385008"
    },
    {
      "nct_id": "NCT02645617",
      "title": "Safety Evaluation of Advantage Anti-Caries Varnish",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Varnish",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Advantage Dental Services, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "36 Months",
        "maximum_age": "60 Months",
        "sex": "ALL",
        "summary": "36 Months to 60 Months"
      },
      "enrollment_count": 12,
      "start_date": "2016-03-30",
      "completion_date": "2016-10-20",
      "has_results": true,
      "last_update_posted_date": "2020-01-21",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02645617"
    },
    {
      "nct_id": "NCT04550546",
      "title": "Effects of Nystatin Suspension Oral Application on Oral Microbial Community",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Nystatin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2021-05-15",
      "completion_date": "2022-02-28",
      "has_results": false,
      "last_update_posted_date": "2022-06-15",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04550546"
    },
    {
      "nct_id": "NCT00660972",
      "title": "Study of Viral Load Decay Rates in HIV Infected Participants Starting Treatment With Raltegravir (RAL) and Emtricitabine/Tenofovir Disoproxil Fumarate (TDF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Raltegravir",
          "type": "DRUG"
        },
        {
          "name": "Emtricitabine/tenofovir disoproxil fumarate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2008-05",
      "completion_date": "2010-04",
      "has_results": false,
      "last_update_posted_date": "2021-11-01",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 15,
      "location_summary": "San Diego, California • Aurora, Colorado • Chicago, Illinois + 10 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00660972"
    },
    {
      "nct_id": "NCT01116726",
      "title": "Promoting Behavioral Change for Oral Health in American Indian Mothers and Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Early Childhood Dental Caries"
      ],
      "interventions": [
        {
          "name": "Motivational interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced community services",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "15 Years to 44 Years"
      },
      "enrollment_count": 1134,
      "start_date": "2011-08",
      "completion_date": "2017-01",
      "has_results": false,
      "last_update_posted_date": "2021-07-08",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01116726"
    },
    {
      "nct_id": "NCT07261137",
      "title": "Efficacy of Solventum™ Vitrebond™ Pulp Protect Liner/Base Used as a Liner/Base Under Dental Restorations",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Caries, Dental",
        "Tooth Decay",
        "Dental Decay",
        "Tooth Sensitivity"
      ],
      "interventions": [
        {
          "name": "Vitrebond™ Pulp Protect Liner/Base",
          "type": "DEVICE"
        },
        {
          "name": "Vitrebond™ Plus (comparator)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Solventum US LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "7 Years to 89 Years"
      },
      "enrollment_count": 5,
      "start_date": "2026-02-17",
      "completion_date": "2026-04-15",
      "has_results": false,
      "last_update_posted_date": "2026-05-06",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07261137"
    },
    {
      "nct_id": "NCT02635867",
      "title": "Clinical Comparison of Vital Pulp Capping Restorative Protocols",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Deep Dental Caries"
      ],
      "interventions": [
        {
          "name": "Indirect Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        },
        {
          "name": "Indirect Pulp capping-Resin-based dentin bonding agent",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Resin-modified calcium silicate - TheraCal",
          "type": "PROCEDURE"
        },
        {
          "name": "Direct Pulp capping-Calcium hydroxide - Dycal",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Illinois at Chicago",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 109,
      "start_date": "2015-06",
      "completion_date": "2019-08",
      "has_results": true,
      "last_update_posted_date": "2023-10-12",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02635867"
    },
    {
      "nct_id": "NCT06173167",
      "title": "Clinical Evaluation of Full Contour Zirconia Chairside CAD/CAM Crowns",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Disorders Hard Tissues of Teeth",
        "Dental Diseases"
      ],
      "interventions": [
        {
          "name": "Crowns self-adhesively luted",
          "type": "DEVICE"
        },
        {
          "name": "Crowns conventionally cemented",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ivoclar Vivadent AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2024-01-08",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-03-28",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06173167"
    },
    {
      "nct_id": "NCT00863668",
      "title": "Raltegravir Activity In Lymphoid Tissues",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "HIV Infection",
        "HIV Infections"
      ],
      "interventions": [
        {
          "name": "Efavirenz + Tenofovir DF/Emtricitabine",
          "type": "DRUG"
        },
        {
          "name": "Raltegravir + Tenofovir DF/Emtricitabine",
          "type": "DRUG"
        },
        {
          "name": "Colonoscopy with biopsies",
          "type": "PROCEDURE"
        },
        {
          "name": "Inguinal Lymph Node Excision",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2009-03",
      "completion_date": "2011-03",
      "has_results": false,
      "last_update_posted_date": "2015-05-18",
      "last_synced_at": "2026-10-11T09:59:04.825Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00863668"
    }
  ]
}