{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Pulp+Necrosis",
    "query": {
      "condition": "Dental Pulp Necrosis"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dental+Pulp+Necrosis&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T07:37:04.115Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06569329",
      "title": "Bacterial Reduction After Supplementary Disinfection Procedures in Infected Root Canals",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Necroses"
      ],
      "interventions": [
        {
          "name": "GentleWave System Root Canal Therapy",
          "type": "DEVICE"
        },
        {
          "name": "EdgePro Laser Root Canal Therapy",
          "type": "DEVICE"
        },
        {
          "name": "The ProUltra Piezo Ultrasonic with EndoUltra Tips Root Canal Therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abhishek Parolia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 90,
      "start_date": "2024-08-20",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06569329"
    },
    {
      "nct_id": "NCT00881907",
      "title": "Tissue Characterization in Teeth Treated With a Regeneration Protocol",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pulp Necrosis"
      ],
      "interventions": [
        {
          "name": "Triple Antibiotic Paste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "10 Years to 60 Years"
      },
      "enrollment_count": 1,
      "start_date": "2010-03",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2016-02-05",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00881907"
    },
    {
      "nct_id": "NCT06843525",
      "title": "Bite Force Measurements",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Irreversible Pulpitis",
        "Apical Periodontitis",
        "Pulpal Necrosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 112,
      "start_date": "2025-05-16",
      "completion_date": "2026-11-01",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Newark, New Jersey",
      "locations": [
        {
          "city": "Newark",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06843525"
    },
    {
      "nct_id": "NCT02477358",
      "title": "The Use of Platelet Rich Fibrin in Pulpal and Periodontal Regeneration in Mature Teeth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulpal Necrosis"
      ],
      "interventions": [
        {
          "name": "Left Tooth Platelet Rich Fibrin; Right Tooth Implant Alone",
          "type": "PROCEDURE"
        },
        {
          "name": "Right Tooth Platelet Rich Fibrin; Left Tooth Implant Alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2014-09-29",
      "completion_date": "2016-06-01",
      "has_results": true,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Lincoln, Nebraska",
      "locations": [
        {
          "city": "Lincoln",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02477358"
    },
    {
      "nct_id": "NCT03053037",
      "title": "Apical Size and Root Canal Treatment Success Trial (AS-RCT Trial)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Root Canal Therapy"
      ],
      "interventions": [
        {
          "name": "final apical size instrumentation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 35,
      "start_date": "2016-08-05",
      "completion_date": "2022-02-07",
      "has_results": false,
      "last_update_posted_date": "2022-02-24",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 2,
      "location_summary": "San Antonio, Texas • Seattle, Washington",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03053037"
    },
    {
      "nct_id": "NCT01827098",
      "title": "A Clinical Study to Compare Two Revascularization Protocols to Treat Non-vital Teeth With Incomplete Root Formation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Pulp Necrosis",
        "Disorder of Tooth Development"
      ],
      "interventions": [
        {
          "name": "Endodontic Regeneration",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "6 Years to 25 Years"
      },
      "enrollment_count": 45,
      "start_date": "2012-10",
      "completion_date": "2023-06-07",
      "has_results": false,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01827098"
    },
    {
      "nct_id": "NCT00881491",
      "title": "Treatment Outcome With a Revascularization Protocol Using the Triple Versus Double Antibiotic Paste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Pulp Necrosis"
      ],
      "interventions": [
        {
          "name": "Double Antibiotic Paste",
          "type": "DRUG"
        },
        {
          "name": "Triple Antibiotic Paste",
          "type": "DRUG"
        },
        {
          "name": "Mineral Trioxide Aggregate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "7 Years to 60 Years"
      },
      "enrollment_count": 10,
      "start_date": "2009-04",
      "completion_date": "2015-01",
      "has_results": false,
      "last_update_posted_date": "2016-02-05",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00881491"
    },
    {
      "nct_id": "NCT03376984",
      "title": "Nanodiamond-Gutta Percha Composite Biomaterials for Root Canal Therapy",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Dental Pulp Diseases",
        "Dental Pulp Necrosis",
        "Nerve Root Pain Nec"
      ],
      "interventions": [
        {
          "name": "ND and AMOX modified Gutta Percha",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Gutta Percha",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "DEVICE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2023-06",
      "completion_date": "2025-06",
      "has_results": false,
      "last_update_posted_date": "2023-09-21",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03376984"
    },
    {
      "nct_id": "NCT06554366",
      "title": "Bacterial Load Reduction by GentleWave and EdgePro Irrigation Systems in Mandibular Necrotic Molars",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulp Necroses"
      ],
      "interventions": [
        {
          "name": "GentleWave",
          "type": "DEVICE"
        },
        {
          "name": "EdgePro laser irrigation",
          "type": "DEVICE"
        },
        {
          "name": "Irrisafe passive ultrasonic irrigation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2024-08-30",
      "completion_date": "2026-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-09-05",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06554366"
    },
    {
      "nct_id": "NCT01976065",
      "title": "Regeneration of Pulp-Dentin Development in Teeth With Necrotic Pulps and Immature Roots",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pulp Necrosis",
        "Regeneration"
      ],
      "interventions": [
        {
          "name": "Triple Antibiotic Paste",
          "type": "DRUG"
        },
        {
          "name": "Standard Treatment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Kenneth Hargreaves",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "6 Years to 20 Years"
      },
      "enrollment_count": 125,
      "start_date": "2014-09",
      "completion_date": "2018-09-24",
      "has_results": false,
      "last_update_posted_date": "2023-09-07",
      "last_synced_at": "2026-05-22T07:37:04.115Z",
      "location_count": 4,
      "location_summary": "Loma Linda, California • Baltimore, Maryland • Chapel Hill, North Carolina + 1 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01976065"
    }
  ]
}