{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Denture+Retention",
    "query": {
      "condition": "Denture Retention"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Denture+Retention&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:05:03.263Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02928380",
      "title": "Evaluation of a Experimental Denture Adhesive to Prevent Food Ingress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Experimental Denture Adhesive",
          "type": "DEVICE"
        },
        {
          "name": "Reference (Marketed) Denture Adhesive",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 83,
      "start_date": "2016-07-25",
      "completion_date": "2016-09-16",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02928380"
    },
    {
      "nct_id": "NCT04473521",
      "title": "A Clinical Study to Assess Force Required to Dislodge Upper Denture With and Without Use of a Novel Denture Adhesive",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Investigational denture adhesive cream",
          "type": "DEVICE"
        },
        {
          "name": "Super Poligrip Free",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-10-04",
      "completion_date": "2021-01-10",
      "has_results": false,
      "last_update_posted_date": "2021-01-22",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04473521"
    },
    {
      "nct_id": "NCT05441527",
      "title": "Use of Two Dissolvable Therapeutics Under Removable Partial Dentures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Edentulous Jaw",
        "Edentulous Mouth"
      ],
      "interventions": [
        {
          "name": "MI Paste, then, Biotene Dry Mouth Gel",
          "type": "DEVICE"
        },
        {
          "name": "Biotene Dry Mouth Gel, then, MI Paste",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Iowa",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 67,
      "start_date": "2022-06-30",
      "completion_date": "2024-05-27",
      "has_results": true,
      "last_update_posted_date": "2025-11-25",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05441527"
    },
    {
      "nct_id": "NCT02937870",
      "title": "A Bite Force Study Comparing Two New Test Adhesives With Currently Marketed Denture Adhesive",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Test Product 1",
          "type": "DEVICE"
        },
        {
          "name": "Test Product 2",
          "type": "DEVICE"
        },
        {
          "name": "Reference Product",
          "type": "DEVICE"
        },
        {
          "name": "Negative Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 25,
      "start_date": "2017-03-07",
      "completion_date": "2017-04-05",
      "has_results": true,
      "last_update_posted_date": "2018-05-23",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Bloomfield, New Jersey",
      "locations": [
        {
          "city": "Bloomfield",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02937870"
    },
    {
      "nct_id": "NCT07273149",
      "title": "A Study to Assess the Effectiveness of a Marketed Denture Adhesive in Real-World Setting",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Poligrip Power Max Hold + Seal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 375,
      "start_date": "2025-12-05",
      "completion_date": "2026-05-21",
      "has_results": false,
      "last_update_posted_date": "2026-06-02",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07273149"
    },
    {
      "nct_id": "NCT03709810",
      "title": "A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Marketed Denture Adhesive (Super Poligrip Max Seal)",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "No Adhesive",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT",
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 49,
      "start_date": "2019-01-07",
      "completion_date": "2019-01-24",
      "has_results": true,
      "last_update_posted_date": "2020-03-02",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03709810"
    },
    {
      "nct_id": "NCT05173974",
      "title": "A Clinical Study to Evaluate the Maximum Maxillary Bite Force (BF) When Using Two Novel Denture Adhesives Compared to Using No-Adhesive",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Super Poligrip Free",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Denture Adhesive 1",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Denture Adhesive 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 45,
      "start_date": "2022-02-08",
      "completion_date": "2022-07-12",
      "has_results": true,
      "last_update_posted_date": "2024-02-16",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05173974"
    },
    {
      "nct_id": "NCT03037307",
      "title": "A Clinical Bite Force Study of Two Marketed Adhesives Against no Adhesive",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Test Product",
          "type": "OTHER"
        },
        {
          "name": "Positive Contol",
          "type": "OTHER"
        },
        {
          "name": "Negative Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 44,
      "start_date": "2017-02-13",
      "completion_date": "2017-05-04",
      "has_results": true,
      "last_update_posted_date": "2018-08-31",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03037307"
    },
    {
      "nct_id": "NCT06083506",
      "title": "Immediate Loading of 4 Guided Implants Supporting a Maxillary Overdenture Using a Novaloc TiN Retention System",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Immediate Dental Implant Loading",
        "Denture, Complete"
      ],
      "interventions": [
        {
          "name": "NOVALOC TiN retained maxillary overdenture",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "West Virginia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2019-01-03",
      "completion_date": "2023-05-15",
      "has_results": true,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Morgantown, West Virginia",
      "locations": [
        {
          "city": "Morgantown",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06083506"
    },
    {
      "nct_id": "NCT07496164",
      "title": "A Clinical Study to Assess the Effectiveness of Use of Three Experimental Denture Adhesives Compared to Using No-Adhesive",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Denture Retention"
      ],
      "interventions": [
        {
          "name": "Experimental Denture Adhesive 1",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Denture Adhesive 2",
          "type": "DEVICE"
        },
        {
          "name": "Experimental Denture Adhesive 3",
          "type": "DEVICE"
        },
        {
          "name": "Poligrip Power Hold + Seal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2026-03-30",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-06-11T04:05:03.263Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07496164"
    }
  ]
}