{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression&page=40",
    "query": {
      "condition": "Depression",
      "page": 40
    },
    "page_size": 10
  },
  "pagination": {
    "page": 40,
    "page_size": 10,
    "total_count": 5333,
    "total_pages": 534,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression&page=41&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression&page=39&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-29T11:56:15.395Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00769015",
      "title": "Low Vision Depression Prevention Trial for Age Related Macular Degeneration",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Age-related Macular Degeneration",
        "Depression"
      ],
      "interventions": [
        {
          "name": "BA-LVR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ST-LVR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 188,
      "start_date": "2009-06",
      "completion_date": "2014-06",
      "has_results": true,
      "last_update_posted_date": "2014-11-20",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00769015"
    },
    {
      "nct_id": "NCT05809115",
      "title": "Neurodevelopmental Outcomes in Children: Strengthening the Caregiver-Child Story",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Food Insecurity",
        "Depression",
        "Anxiety"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Baylor College of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2023-06-14",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05809115"
    },
    {
      "nct_id": "NCT02351843",
      "title": "Efficacy and Safety of Low Amplitude Electroconvulsive Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "MECTA Spectrum 5000Q",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 1,
      "start_date": "2015-02",
      "completion_date": "2015-11",
      "has_results": false,
      "last_update_posted_date": "2017-03-22",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02351843"
    },
    {
      "nct_id": "NCT00044174",
      "title": "Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Months",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "5 Months and older"
      },
      "enrollment_count": 701,
      "start_date": "2002-08-20",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-09-24",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00044174"
    },
    {
      "nct_id": "NCT04231097",
      "title": "MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Coronary Syndrome",
        "Depression",
        "Myocardial Infarction",
        "Unstable Angina",
        "STEMI",
        "NSTEMI - Non-ST Segment Elevation MI"
      ],
      "interventions": [
        {
          "name": "MBCT intervention for ACS patients",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "35 Years to 85 Years"
      },
      "enrollment_count": 8,
      "start_date": "2020-04-24",
      "completion_date": "2021-03-01",
      "has_results": true,
      "last_update_posted_date": "2023-04-24",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04231097"
    },
    {
      "nct_id": "NCT00222820",
      "title": "Depression: The Search for Treatment-Relevant Phenotypes-Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Depression"
      ],
      "interventions": [
        {
          "name": "escitalopram",
          "type": "DRUG"
        },
        {
          "name": "Interpersonal Psychotherapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 35,
      "start_date": "2002-04",
      "completion_date": "2004-09",
      "has_results": false,
      "last_update_posted_date": "2005-09-22",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00222820"
    },
    {
      "nct_id": "NCT07326748",
      "title": "Lakota Family Acceptance Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "LGBTQ",
        "Racial Disparities",
        "Family Relationships",
        "Minority Stress",
        "Depression",
        "Anxiety",
        "Drug Use",
        "Teen Dating Violence",
        "Sexual Risk Reduction"
      ],
      "interventions": [
        {
          "name": "Adapted Lakota Family Acceptance Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "13 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2026-01-20",
      "completion_date": "2026-08-12",
      "has_results": false,
      "last_update_posted_date": "2026-09-01",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 2,
      "location_summary": "Pine Ridge, South Dakota • Rapid City, South Dakota",
      "locations": [
        {
          "city": "Pine Ridge",
          "state": "South Dakota"
        },
        {
          "city": "Rapid City",
          "state": "South Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07326748"
    },
    {
      "nct_id": "NCT00634608",
      "title": "Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Allergic Rhinitis",
        "Asthma",
        "Back Pain",
        "Benign Prostatic Hypertrophy",
        "Bursitis",
        "Depression",
        "Anxiety",
        "Diabetes Mellitus",
        "Esophageal Reflux",
        "HIV Infections",
        "Hyperlipidemia",
        "Hypertension",
        "Insomnia",
        "Irritable Bowel Syndrome",
        "Obesity",
        "Osteoporosis (Senile)",
        "Shoulder Pain",
        "Sinusitis",
        "Symptomatic Menopause",
        "Urinary Incontinence",
        "Urinary Tract Infection",
        "Vaginitis"
      ],
      "interventions": [
        {
          "name": "Health Information Prescription",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 224,
      "start_date": "2008-02",
      "completion_date": "2009-09",
      "has_results": false,
      "last_update_posted_date": "2016-09-30",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00634608"
    },
    {
      "nct_id": "NCT06923423",
      "title": "Effectiveness, Implementation, and Cost of Cognitive Processing Therapy in Prisons",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "PTSD - Post Traumatic Stress Disorder",
        "PTSD and Alcohol Use Disorder",
        "PTSD and Trauma-related Symptoms",
        "Substance Use Disorder (SUD)",
        "Depression",
        "Mental Health",
        "Trauma",
        "Trauma Exposure",
        "Traumatic Stress Disorder",
        "Traumatic Stress",
        "Post Traumatic Stress Symptoms"
      ],
      "interventions": [
        {
          "name": "Group Cognitive Processing Therapy (CPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control Group Individual trauma focused self-help via workbook",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 640,
      "start_date": "2025-07-07",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-21",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 6,
      "location_summary": "Little Rock, Arkansas • Osceola, Arkansas • Texarkana, Arkansas + 2 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Osceola",
          "state": "Arkansas"
        },
        {
          "city": "Texarkana",
          "state": "Arkansas"
        },
        {
          "city": "West Memphis",
          "state": "Arkansas"
        },
        {
          "city": "Bismarck",
          "state": "North Dakota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06923423"
    },
    {
      "nct_id": "NCT02358343",
      "title": "A Trial of Sertraline vs. CBT for End-stage Renal Disease Patients With Depression {ASCEND}",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Depression",
        "End Stage Renal Disease"
      ],
      "interventions": [
        {
          "name": "Engagement Interview",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Antidepressant Drug Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 184,
      "start_date": "2015-03-23",
      "completion_date": "2017-12-15",
      "has_results": true,
      "last_update_posted_date": "2019-07-23",
      "last_synced_at": "2026-10-29T11:56:15.395Z",
      "location_count": 3,
      "location_summary": "Albuquerque, New Mexico • Dallas, Texas • Seattle, Washington",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02358343"
    }
  ]
}