{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+Disorders&page=14",
    "query": {
      "condition": "Depression Disorders",
      "page": 14
    },
    "page_size": 10
  },
  "pagination": {
    "page": 14,
    "page_size": 10,
    "total_count": 4436,
    "total_pages": 444,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+Disorders&page=15&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+Disorders&page=13&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T08:06:45.973Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00406848",
      "title": "A Study Comparing the Efficacy and Safety of Duloxetine and Placebo for the Treatment of Depression in Elderly Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "duloxetine hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eli Lilly and Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 370,
      "start_date": "2006-11",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2010-09-29",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 23,
      "location_summary": "Pasadena, California • Sherman Oaks, California • Hamden, Connecticut + 20 more",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        },
        {
          "city": "Sherman Oaks",
          "state": "California"
        },
        {
          "city": "Hamden",
          "state": "Connecticut"
        },
        {
          "city": "Coral Springs",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00406848"
    },
    {
      "nct_id": "NCT02614443",
      "title": "Effectiveness and Acceptability of Internet-delivered Treatment for Depression, Anxiety and Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Space from Depression",
          "type": "OTHER"
        },
        {
          "name": "Space from Anxiety",
          "type": "OTHER"
        },
        {
          "name": "Space from Stress",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Silver Cloud Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2015-10",
      "completion_date": "2017-09",
      "has_results": false,
      "last_update_posted_date": "2018-09-11",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02614443"
    },
    {
      "nct_id": "NCT02330744",
      "title": "The Neurobiology of Approach Avoidance Training in Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Approach-positive AAT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control AAT",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 40,
      "start_date": "2014-07",
      "completion_date": "2017-07",
      "has_results": false,
      "last_update_posted_date": "2017-09-01",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02330744"
    },
    {
      "nct_id": "NCT01689909",
      "title": "Reducing Suicidal Ideation Through Insomnia Treatment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Insomnia",
        "Depression",
        "Suicidal Ideation"
      ],
      "interventions": [
        {
          "name": "Zolpidem-CR",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 103,
      "start_date": "2012-12-06",
      "completion_date": "2018-01-01",
      "has_results": true,
      "last_update_posted_date": "2022-02-16",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 4,
      "location_summary": "Augusta, Georgia • Durham, North Carolina • Wake Forest, North Carolina + 1 more",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Wake Forest",
          "state": "North Carolina"
        },
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01689909"
    },
    {
      "nct_id": "NCT04120285",
      "title": "Appalachian Mind Health Initiative",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "remote internet-based cognitive behavior therapy (eCBT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of South Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1280,
      "start_date": "2021-01-09",
      "completion_date": "2026-01-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-27",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 7,
      "location_summary": "Louisville, Kentucky • Cedar Grove, West Virginia • Glenville, West Virginia + 4 more",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Cedar Grove",
          "state": "West Virginia"
        },
        {
          "city": "Glenville",
          "state": "West Virginia"
        },
        {
          "city": "Grantsville",
          "state": "West Virginia"
        },
        {
          "city": "Harpers Ferry",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04120285"
    },
    {
      "nct_id": "NCT01479829",
      "title": "Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Bipolar Depression"
      ],
      "interventions": [
        {
          "name": "Escitalopram",
          "type": "DRUG"
        },
        {
          "name": "Celecoxib",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Loyola University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 100,
      "start_date": "2011-03-23",
      "completion_date": "2018-01-24",
      "has_results": true,
      "last_update_posted_date": "2024-04-29",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Maywood, Illinois",
      "locations": [
        {
          "city": "Maywood",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01479829"
    },
    {
      "nct_id": "NCT07170657",
      "title": "Teen Recovery Through Inspiration, Support, and Empowerment",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Suicidal Ideation",
        "Suicide Attempt",
        "Anxiety",
        "Depression Disorders"
      ],
      "interventions": [
        {
          "name": "Peer Support Services Recovery",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "15 Years to 18 Years"
      },
      "enrollment_count": 40,
      "start_date": "2025-11-05",
      "completion_date": "2026-11",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07170657"
    },
    {
      "nct_id": "NCT06166095",
      "title": "Dose-Response Effect Exercise and Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "high-dose",
          "type": "OTHER"
        },
        {
          "name": "Walking attention control",
          "type": "OTHER"
        },
        {
          "name": "moderate-dose",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Central Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "18 Years to 25 Years"
      },
      "enrollment_count": 48,
      "start_date": "2023-07-01",
      "completion_date": "2024-12-01",
      "has_results": false,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06166095"
    },
    {
      "nct_id": "NCT02522377",
      "title": "Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Treatment Resistant Depression",
        "Major Depressive Disorder",
        "Severe Depression"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 15,
      "start_date": "2015-08",
      "completion_date": "2018-03-01",
      "has_results": true,
      "last_update_posted_date": "2019-08-29",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02522377"
    },
    {
      "nct_id": "NCT00007267",
      "title": "Psychological Treatments for Scleroderma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pain",
        "Depression",
        "Scleroderma",
        "Systemic Sclerosis"
      ],
      "interventions": [
        {
          "name": "Cognitive behavioral therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Disease/health education",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self-help cognitive behavioral intervention facilitated by a psychologist",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 89,
      "start_date": "2001-06",
      "completion_date": "2006-06",
      "has_results": false,
      "last_update_posted_date": "2017-08-09",
      "last_synced_at": "2026-10-22T08:06:45.973Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00007267"
    }
  ]
}