{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and%2For+Anxiety+Symptoms&page=2", "query": { "condition": "Depression and/or Anxiety Symptoms", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 72, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and%2For+Anxiety+Symptoms&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and%2For+Anxiety+Symptoms&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-08T10:48:24.989Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00330174", "title": "Acamprosate in Alcoholics With Comorbid Anxiety or Depression", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Alcohol Dependence", "Major Depression", "Social Anxiety Disorder", "Generalized Anxiety Disorder" ], "interventions": [ { "name": "Acamprosate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Medical University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 90, "start_date": "2006-04", "completion_date": "2010-09", "has_results": true, "last_update_posted_date": "2015-04-13", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 3, "location_summary": "Belmont, Massachusetts • New York, New York • Pickens, South Carolina", "locations": [ { "city": "Belmont", "state": "Massachusetts" }, { "city": "New York", "state": "New York" }, { "city": "Pickens", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00330174" }, { "nct_id": "NCT04931927", "title": "Impact of Telehealth on Engagement in Psychotherapy and/or Medication Treatment", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Psychiatric Diagnosis" ], "interventions": [ { "name": "Making Connections Intervention-Telehealth (MCI-T)", "type": "BEHAVIORAL" }, { "name": "Treatment as usual (TAU)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "New York State Psychiatric Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "18 Years", "sex": "ALL", "summary": "12 Years to 18 Years" }, "enrollment_count": 14, "start_date": "2021-11-08", "completion_date": "2022-07-12", "has_results": false, "last_update_posted_date": "2022-07-28", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04931927" }, { "nct_id": "NCT02878928", "title": "Clinical Study Evaluating Effects of Pharmacogenetic-guided vs Standard-of-Care Treatment on Depression and/or Anxiety", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Depression", "Anxiety" ], "interventions": [ { "name": "IDgenetix Neuropsychiatric Test Panel", "type": "GENETIC" } ], "intervention_types": [ "GENETIC" ], "sponsor": "AltheaDx", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 579, "start_date": "2016-05", "completion_date": "2016-12", "has_results": false, "last_update_posted_date": "2016-12-19", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 17, "location_summary": "Rolling Hills, California • San Diego, California • Torrance, California + 13 more", "locations": [ { "city": "Rolling Hills", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Torrance", "state": "California" }, { "city": "Lauderhill", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02878928" }, { "nct_id": "NCT07161700", "title": "An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Major Depressive Disorder (MDD)", "Major Depressive Disorder With Anxious Distress" ], "interventions": [ { "name": "SPT-300", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Seaport Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "66 Years", "sex": "ALL", "summary": "18 Years to 66 Years" }, "enrollment_count": 360, "start_date": "2025-09-02", "completion_date": "2027-05", "has_results": false, "last_update_posted_date": "2026-10-06", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 20, "location_summary": "Chino, California • Garden Grove, California • Glendale, California + 17 more", "locations": [ { "city": "Chino", "state": "California" }, { "city": "Garden Grove", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "San Jose", "state": "California" }, { "city": "Cromwell", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT07161700" }, { "nct_id": "NCT01764789", "title": "Stress Reduction in Improving Quality of Life in Patients With Recurrent Gynecologic or Breast Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Anxiety Disorder", "Depression", "Fatigue", "Leydig Cell Tumor", "Ovarian Sarcoma", "Ovarian Stromal Cancer", "Pain", "Peritoneal Carcinomatosis", "Pseudomyxoma Peritonei", "Recurrent Breast Cancer", "Recurrent Cervical Cancer", "Recurrent Endometrial Carcinoma", "Recurrent Fallopian Tube Cancer", "Recurrent Gestational Trophoblastic Tumor", "Recurrent Ovarian Epithelial Cancer", "Recurrent Ovarian Germ Cell Tumor", "Recurrent Primary Peritoneal Cavity Cancer", "Recurrent Uterine Sarcoma", "Recurrent Vaginal Cancer", "Recurrent Vulvar Cancer" ], "interventions": [ { "name": "questionnaire administration", "type": "OTHER" }, { "name": "quality-of-life assessment", "type": "PROCEDURE" }, { "name": "psychosocial assessment and care", "type": "PROCEDURE" }, { "name": "behavioral intervention", "type": "BEHAVIORAL" }, { "name": "cognitive intervention", "type": "OTHER" }, { "name": "educational intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER", "PROCEDURE", "BEHAVIORAL" ], "sponsor": "Ohio State University Comprehensive Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "85 Years", "sex": "FEMALE", "summary": "21 Years to 85 Years · Female only" }, "enrollment_count": 39, "start_date": "2010-10", "completion_date": "2012-01", "has_results": false, "last_update_posted_date": "2015-10-09", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "Columbus, Ohio", "locations": [ { "city": "Columbus", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01764789" }, { "nct_id": "NCT06835504", "title": "Morphine or Ketamine for Analgesia", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Abdominal Pain", "Isolated Extremity Fracture", "Pain", "Pediatrics" ], "interventions": [ { "name": "Ketamine hydrochloride", "type": "DRUG" }, { "name": "Morphine sulphate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "6 Years to 17 Years" }, "enrollment_count": 1010, "start_date": "2026-09-01", "completion_date": "2030-02-28", "has_results": false, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 8, "location_summary": "Los Angeles, California • Sacramento, California • Wilmington, Delaware + 5 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Sacramento", "state": "California" }, { "city": "Wilmington", "state": "Delaware" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06835504" }, { "nct_id": "NCT00395213", "title": "Antidepressant Safety in Kids Study", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Anxiety Disorders", "Depressive Disorders", "Eating Disorders", "Obsessive Compulsive Disorder" ], "interventions": [ { "name": "Selective serotonin reuptake inhibitor (SSRI) and serotonin-norepinephrine reuptake inhibitor (SNRI) medications", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "7 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "7 Years to 17 Years" }, "enrollment_count": 569, "start_date": "2007-05", "completion_date": "2009-07", "has_results": false, "last_update_posted_date": "2015-04-17", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00395213" }, { "nct_id": "NCT06999109", "title": "Teams Engaged in Accessible Mental Health Interventions for Lupus Erythematosus and Dermatomyositis Stress", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Lupus", "Dermatomyositis, Juvenile", "Dermatomyositis", "Lupus Erythematosus", "Lupus Erythematosus, Systemic", "Lupus or SLE" ], "interventions": [ { "name": "TEAM-LEADS", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Duke University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": "22 Years", "sex": "ALL", "summary": "13 Years to 22 Years" }, "enrollment_count": 25, "start_date": "2027-02-01", "completion_date": "2029-01-15", "has_results": false, "last_update_posted_date": "2026-05-27", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "Durham, North Carolina", "locations": [ { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06999109" }, { "nct_id": "NCT07216638", "title": "Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Implementation Research", "Depressive Disorder", "ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)", "Conduct Disorders in Children", "Pediatric Mental Health Services" ], "interventions": [], "intervention_types": [], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": null, "sex": "ALL", "summary": "5 Years and older" }, "enrollment_count": 575, "start_date": "2023-11-28", "completion_date": "2028-08", "has_results": false, "last_update_posted_date": "2025-10-14", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07216638" }, { "nct_id": "NCT05189977", "title": "A Trial to Assess the Effects of Prazosin or Propranolol on Blood Pressure in the Presence of Brexpiprazole/Sertraline", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Post-traumatic Stress Disorder (PTSD)" ], "interventions": [ { "name": "Propranolol", "type": "DRUG" }, { "name": "Prazosin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 34, "start_date": "2022-09-07", "completion_date": "2023-08-03", "has_results": false, "last_update_posted_date": "2024-01-23", "last_synced_at": "2026-10-08T10:48:24.989Z", "location_count": 1, "location_summary": "Princeton, New Jersey", "locations": [ { "city": "Princeton", "state": "New Jersey" } ], "official_url": "https://clinicaltrials.gov/study/NCT05189977" } ] }