{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=26", "query": { "condition": "Depression and Anxiety Symptoms", "page": 26 }, "page_size": 10 }, "pagination": { "page": 26, "page_size": 10, "total_count": 1044, "total_pages": 105, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=27&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=25&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-15T09:31:45.379Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04032301", "title": "Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Post-Traumatic Stress Disorders", "Major Depressive Disorder" ], "interventions": [ { "name": "Ketamine", "type": "DRUG" }, { "name": "Normal Saline", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 67, "start_date": "2019-09-30", "completion_date": "2024-11-10", "has_results": false, "last_update_posted_date": "2025-06-27", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT04032301" }, { "nct_id": "NCT05685511", "title": "Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Older Adults", "Anxiety", "Depression", "Major Surgical Resection of a Thoracic Malignancy", "Major Surgical Resection of an Abdominal Malignancy" ], "interventions": [ { "name": "Behavioral Activation", "type": "BEHAVIORAL" }, { "name": "Medication Optimization", "type": "OTHER" }, { "name": "Usual care resources", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "60 Years", "maximum_age": null, "sex": "ALL", "summary": "60 Years and older" }, "enrollment_count": 105, "start_date": "2023-03-10", "completion_date": "2024-07-12", "has_results": true, "last_update_posted_date": "2026-03-31", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT05685511" }, { "nct_id": "NCT04031469", "title": "A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease", "overall_status": "SUSPENDED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Gut Microbiome", "Gastrointestinal Microbiome", "Autism", "Autism Spectrum Disorder", "Autism Spectrum Disorder High-Functioning", "Alzheimer Disease", "Alzheimer Dementia (AD)", "Alzheimer Dementia", "Alzheimer Disease (AD)", "Crohn", "Crohn Colitis", "Crohn Disease (CD)", "Crohn Disease Colon", "Myalgic Encephalomyelitis", "ME/CFS", "Myalgic Encephalomyelitis (ME)", "Myalgic Encephalomyelitis/Chronic Fatigue Syndrome", "Psoriasis", "Psoriasis Annularis", "Psoriasis Chronic", "Chronic Urinary Tract Infection", "Ulcerative Colitis (Disorder)", "Ulcerative Colitis (UC)", "Ulcerative Colitis Acute", "Ulcerative Colitis Chronic", "Multiple Sclerosis", "Multiple Sclerosis (MS) - Relapsing-remitting", "Multiple Sclerosis (MS) Primary Progressive", "Constipation Chronic Idiopathic", "Constipation", "Celiac", "Celiac Disease", "Celiac Sprue", "Lyme Arthritis", "Lyme Borreliosis, Nervous System", "Lyme Disease, Chronic", "Cholesterol", "Cholesterol Level, High", "Cancer", "Colon Cancer", "Amyotrophic Lateral Sclerosis (ALS)", "Amyotrophic Lateral Sclerosis", "Rheumatoid Arthritis (RA)", "Rheumatoid Arthritis - Rheumatism", "Chronic Fatigue Syndrome (CFS)", "PARKINSON DISEASE (Disorder)", "Parkinson Disease", "Parkinson Disease (PD)", "Depression", "Major Depressive Disorder (MDD)", "Depression Disorder", "Depression in Adults", "Anxiety", "Anxiety Disorder Generalized", "Obsessive Compulsive Disorder (OCD)", "Obsessive Compulsive Disorder OCD", "Obsessive - Compulsive Disorder", "Bipolar", "Bipolar 1 Disorder", "Bipolar Disorder (BD)", "Bipolar Disorder I and II", "Bipolar and Related Disorders", "Migraine", "Migraine Disorder", "Diabetes (DM)", "Diabetes", "Lupus", "Lupus Erythematosus", "Epidermolysis Bullosa (EB)", "Mesothelioma", "Mesothelioma Malignant", "IBS (Irritable Bowel Syndrome)", "Irritable Bowel", "IBS - Irritable Bowel Syndrome", "Irritable Bowel Syndrome (IBS)", "Eczema", "Eczema Atopic Dermatitis", "Acne", "Myasthaenia Gravis", "Gout" ], "interventions": [ { "name": "There is no intervention in this study", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "ProgenaBiome", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "12 Years", "maximum_age": null, "sex": "ALL", "summary": "12 Years and older" }, "enrollment_count": 1000, "start_date": "2019-07-11", "completion_date": "2030-12-10", "has_results": false, "last_update_posted_date": "2026-09-21", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Ventura, California", "locations": [ { "city": "Ventura", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04031469" }, { "nct_id": "NCT03951454", "title": "Taking Time to Connect: A Study of Programs for Hispanic Mothers Diagnosed With Cancer and Their Children", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cancer Survivorship" ], "interventions": [ { "name": "Conexiones", "type": "BEHAVIORAL" }, { "name": "Taking Time", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "New Mexico State University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "18 Years to 60 Years · Female only" }, "enrollment_count": 43, "start_date": "2019-04-16", "completion_date": "2022-09-30", "has_results": false, "last_update_posted_date": "2023-02-22", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 5, "location_summary": "Las Cruces, New Mexico • El Paso, Texas • San Antonio, Texas", "locations": [ { "city": "Las Cruces", "state": "New Mexico" }, { "city": "Las Cruces", "state": "New Mexico" }, { "city": "El Paso", "state": "Texas" }, { "city": "El Paso", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT03951454" }, { "nct_id": "NCT04154423", "title": "Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Premature Birth", "Pregnancy Preterm", "Prenatal Stress", "Depression, Anxiety", "Depression, Postpartum", "Satisfaction, Patient", "Health Problems in Pregnancy" ], "interventions": [ { "name": "Glow! Group Prenatal Care", "type": "OTHER" }, { "name": "Individual Prenatal Care with CPSP", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "FEMALE", "summary": "Female only" }, "enrollment_count": 678, "start_date": "2019-11-07", "completion_date": "2024-12-23", "has_results": true, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 2, "location_summary": "Fresno, California • San Francisco, California", "locations": [ { "city": "Fresno", "state": "California" }, { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04154423" }, { "nct_id": "NCT03595254", "title": "Digital Cognitive Behavior Therapy Program for Suicide Prevention", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Suicidal Ideation", "Depression", "Anxiety" ], "interventions": [ { "name": "Thrive", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Montana State University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 725, "start_date": "2018-11-16", "completion_date": "2020-04-08", "has_results": false, "last_update_posted_date": "2020-09-02", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Bozeman, Montana", "locations": [ { "city": "Bozeman", "state": "Montana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03595254" }, { "nct_id": "NCT07346183", "title": "CommunityRx-Dementia + Peer Navigation (CRxDpeer)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alzheimer s Disease", "Dementia", "Caregiver", "Loneliness", "Health-Related Social Needs", "Social Care", "Healthcare Utilization", "End of Life Care", "Caregiver Burden", "Anxiety", "Stress", "Depression", "Self-Efficacy", "Peer Support", "Implementation Science", "Advance Care Planning" ], "interventions": [ { "name": "CommunityRx-Dpeer", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 330, "start_date": "2026-10-05", "completion_date": "2029-02-28", "has_results": false, "last_update_posted_date": "2026-10-13", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT07346183" }, { "nct_id": "NCT03411057", "title": "Mindfulness Based Stress Reduction in Rheumatic Diseases", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis", "Psoriatic Arthritis", "Scleroderma" ], "interventions": [ { "name": "Mindfulness Based Stress Reduction (MBSR)", "type": "BEHAVIORAL" }, { "name": "Control", "type": "OTHER" } ], "intervention_types": [ "BEHAVIORAL", "OTHER" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 5, "start_date": "2018-01-18", "completion_date": "2021-04-22", "has_results": false, "last_update_posted_date": "2021-04-26", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT03411057" }, { "nct_id": "NCT00737399", "title": "Anxiety and Depression Levels in Cancer Patients After Self-Application of EFT (Emotional Freedom Techniques)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Lifestyle Counseling with Emotional Freedom Techniques (EFT)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "Soul Medicine Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "89 Years", "sex": "ALL", "summary": "18 Years to 89 Years" }, "enrollment_count": 14, "start_date": "2008-09-20", "completion_date": "2028-12-25", "has_results": false, "last_update_posted_date": "2026-04-27", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Santa Rosa, California", "locations": [ { "city": "Santa Rosa", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00737399" }, { "nct_id": "NCT06587230", "title": "Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Child Behavior", "Mental Health Issue", "Psychosocial Functioning", "Depression", "Anxiety" ], "interventions": [ { "name": "Teachers Leading the Frontlines", "type": "BEHAVIORAL" }, { "name": "Responding to Students' Emotions Through Education", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of North Carolina, Chapel Hill", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "5 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "5 Years to 99 Years" }, "enrollment_count": 312, "start_date": "2024-10-08", "completion_date": "2027-06", "has_results": false, "last_update_posted_date": "2026-09-03", "last_synced_at": "2026-10-15T09:31:45.379Z", "location_count": 1, "location_summary": "Chapel Hill, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT06587230" } ] }