{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=3",
    "query": {
      "condition": "Depression and Anxiety Symptoms",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 1041,
    "total_pages": 105,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Anxiety+Symptoms&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T17:36:47.705Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05837351",
      "title": "The CARE (Collaborative Adolescent Running Experience) Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anxiety",
        "Major Depressive Disorder",
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "Exercise -Running",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 4,
      "start_date": "2023-12-05",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2024-06-13",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05837351"
    },
    {
      "nct_id": "NCT06710431",
      "title": "A Study of the Safety and Exploratory Efficacy of Oral AFA-281 in Patients with Alcohol Use Disorder",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Alcohol Abuse",
        "Alcohol Abuse/addiction",
        "Anxiety",
        "Pain Threshold",
        "Depression Disorders",
        "Sleep Disorder"
      ],
      "interventions": [
        {
          "name": "AFA-281",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Afasci Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2025-10-01",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2024-11-29",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06710431"
    },
    {
      "nct_id": "NCT02256566",
      "title": "Cognitive Training for Mood and Anxiety Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Depression",
        "Bipolar Disorder",
        "Post-traumatic Stress Disorder",
        "Generalized Anxiety Disorder",
        "Social Phobia"
      ],
      "interventions": [
        {
          "name": "emotional memory training exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "memory training exercise",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 28,
      "start_date": "2014-09",
      "completion_date": "2016-04-20",
      "has_results": false,
      "last_update_posted_date": "2017-07-21",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02256566"
    },
    {
      "nct_id": "NCT04225624",
      "title": "Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obsessive-Compulsive Disorder",
        "Generalized Anxiety Disorder",
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Emotion Regulation Therapy - Attention Regulation (AR-ERT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Supportive Psychotherapy (SPT)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 65,
      "start_date": "2021-04-30",
      "completion_date": "2025-04-09",
      "has_results": true,
      "last_update_posted_date": "2026-03-10",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04225624"
    },
    {
      "nct_id": "NCT05866705",
      "title": "The Mental Health Experiences of Sexual and Gender Minorities Living With Cancer and Their Care Partners",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety",
        "Caregiver Burden",
        "Stress",
        "Chronic Illness"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2023-04-03",
      "completion_date": "2024-08-27",
      "has_results": false,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05866705"
    },
    {
      "nct_id": "NCT01680172",
      "title": "Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cancer",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Ketamine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2012-08",
      "completion_date": "2015-02",
      "has_results": true,
      "last_update_posted_date": "2016-02-29",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 2,
      "location_summary": "Scottsdale, Arizona • Yuma, Arizona",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Yuma",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01680172"
    },
    {
      "nct_id": "NCT05120232",
      "title": "Flourishing and Virtue in Cognitive-Behavioral Therapy for Anxiety and Depressive Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety Disorders",
        "Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Unified Protocol",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Modified Unified Protocol (UP+)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Boston University Charles River Campus",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2021-03-08",
      "completion_date": "2024-01-16",
      "has_results": false,
      "last_update_posted_date": "2025-02-07",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05120232"
    },
    {
      "nct_id": "NCT03654599",
      "title": "Effects of Digital Stories Intervention on Psychosocial Well-being",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Marrow Transplant",
        "Information Disclosure",
        "Hematopoietic Stem Cell Transplantation",
        "Psychosocial Health",
        "Depression",
        "Anxiety",
        "Stress",
        "Narrative"
      ],
      "interventions": [
        {
          "name": "Baseline Surveys",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Digital Stories Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Information Control Intervention",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Arizona State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 202,
      "start_date": "2017-09-01",
      "completion_date": "2021-07-23",
      "has_results": true,
      "last_update_posted_date": "2024-10-09",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03654599"
    },
    {
      "nct_id": "NCT02072252",
      "title": "Mobile Phone App for Depression and Anxiety in Young Men Who Are Attracted to Men",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Depressive Symptoms",
        "Anxiety Generalized"
      ],
      "interventions": [
        {
          "name": "Mobile Phone Application",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": "20 Years",
        "sex": "MALE",
        "summary": "17 Years to 20 Years · Male only"
      },
      "enrollment_count": 0,
      "start_date": "2017-08-14",
      "completion_date": "2017-08-14",
      "has_results": false,
      "last_update_posted_date": "2017-08-17",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02072252"
    },
    {
      "nct_id": "NCT07364799",
      "title": "Effectiveness of the SoundHeal Multi-Sensory Integrative Therapy Among Justice-Involved Youth",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotional Dysregulation",
        "Therapeutic Alliance",
        "Depression Disorder",
        "Anxiety Disorders",
        "Stress Disorders",
        "Substance Use Disorders",
        "Mental Health Disorders"
      ],
      "interventions": [
        {
          "name": "Multi-sensory emotional regulation intervention (Heal)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "SoundHeal",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "12 Years to 18 Years"
      },
      "enrollment_count": 12,
      "start_date": "2026-01-30",
      "completion_date": "2026-04",
      "has_results": false,
      "last_update_posted_date": "2026-01-23",
      "last_synced_at": "2026-10-10T17:36:47.705Z",
      "location_count": 1,
      "location_summary": "San Luis Obispo, California",
      "locations": [
        {
          "city": "San Luis Obispo",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07364799"
    }
  ]
}