{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+CVD",
    "query": {
      "condition": "Depression and CVD"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 170,
    "total_pages": 17,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+CVD&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T05:34:23.425Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02246413",
      "title": "Research Aimed at Improving Both Mood and Weight",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "RAINBOW Intervention Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Palo Alto Medical Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 409,
      "start_date": "2014-09-30",
      "completion_date": "2018-12-21",
      "has_results": true,
      "last_update_posted_date": "2024-04-26",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • Stanford, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02246413"
    },
    {
      "nct_id": "NCT02454426",
      "title": "Vortioxetine in Patients With Major Depressive Disorder and Coronary Artery Disease",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Major Depressive Disorder",
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Vortioxetine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2016-04",
      "completion_date": "2016-06",
      "has_results": false,
      "last_update_posted_date": "2016-08-25",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02454426"
    },
    {
      "nct_id": "NCT01794455",
      "title": "Effects of Cerebral Hypoperfusion and Its Reversal on Late-Life Depression",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Sertraline",
          "type": "DRUG"
        },
        {
          "name": "Candesartan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2013-05",
      "completion_date": "2015-03",
      "has_results": true,
      "last_update_posted_date": "2016-10-20",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01794455"
    },
    {
      "nct_id": "NCT03349918",
      "title": "PERsonal ContExtual Precision healTh",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Mobile Health Monitoring",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 164,
      "start_date": "2017-11-06",
      "completion_date": "2018-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-03-05",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03349918"
    },
    {
      "nct_id": "NCT04806620",
      "title": "Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Post-Acute COVID-19 Syndrome",
        "ME/CFS",
        "Rheumatic Arthritis",
        "Juvenile Rheumatoid Arthritis (JRA)",
        "Psoriatic Arthritis (PsA)",
        "Ankylosing Spondylitis (AS)",
        "Autoimmune Encephalitis",
        "Celiac Disease",
        "Celiac Disease in Children",
        "Chronic Lyme Disease",
        "Post-treatment Lyme Disease Syndrome",
        "Crohn's Disease",
        "Dysautonomia",
        "Anorexia Nervosa",
        "Bulimia Nervosa",
        "ARFID",
        "Avoidant / Restrictive Food Intake Disorder",
        "Ehlers Danlos Syndrome",
        "Endometriosis",
        "Fibromyalgia (FM)",
        "Long COVID",
        "Lupus",
        "Migraines",
        "Mast Cell Activation Syndrome",
        "Multiple Sclerosis",
        "Myalgic Encephalomyelitis (ME)",
        "Myasthenia Gravis, Generalized",
        "Myasthenia Gravis in Children",
        "Narcolepsy",
        "Obsessive Compulsive Disorder (OCD)",
        "PANDAS",
        "Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)",
        "POTS - Postural Orthostatic Tachycardia Syndrome",
        "General Anxiety Disorder, Social Anxiety Disorder",
        "PTSD - Post Traumatic Stress Disorder",
        "Psoriasis",
        "Traumatic Brain Injury",
        "Tourette's Syndrome",
        "Inflammatory Bowel Disease (IBD)",
        "Autoimmune Diseases",
        "Neurological Diseases or Conditions",
        "Psychiatric Disorder",
        "Sjogren&#39;s Syndrome",
        "Ulcerative Colitis and Crohn&#39;s Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Brain Inflammation Collaborative",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "2 Years and older"
      },
      "enrollment_count": 10000,
      "start_date": "2023-07-05",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Delafield, Wisconsin",
      "locations": [
        {
          "city": "Delafield",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04806620"
    },
    {
      "nct_id": "NCT04682769",
      "title": "Cardiac Markers in Depressed Patients With Coronary Heart Disease - R01HL147862",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Heart Disease",
        "Depression"
      ],
      "interventions": [
        {
          "name": "Other",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2020-12-01",
      "completion_date": "2025-05-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-24",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04682769"
    },
    {
      "nct_id": "NCT06595251",
      "title": "Community Park-Based Programs for Health Promotion: Fit2Play Prospective Cohort Study",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Overweight",
        "Obesity",
        "Hypertension",
        "Prehypertension",
        "Anxiety",
        "Well-being",
        "Depression",
        "Low Physical Fitness",
        "Psychological"
      ],
      "interventions": [
        {
          "name": "Fit2Play curriculum",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Years to 14 Years"
      },
      "enrollment_count": 5000,
      "start_date": "2020-05-07",
      "completion_date": "2027-05-17",
      "has_results": false,
      "last_update_posted_date": "2025-09-04",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06595251"
    },
    {
      "nct_id": "NCT00468676",
      "title": "Nurse-led Case Management for Diabetes and Cardiovascular Disease Patients With Depression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression"
      ],
      "interventions": [
        {
          "name": "Nurse-led case management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 214,
      "start_date": "2007-05",
      "completion_date": "2012-08",
      "has_results": true,
      "last_update_posted_date": "2014-05-02",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00468676"
    },
    {
      "nct_id": "NCT01461681",
      "title": "Improving Care of Patients With Heart Failure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Pain",
        "Dyspnea",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Symptom Management Service for Heart failure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2012-03",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-05-14",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 2,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01461681"
    },
    {
      "nct_id": "NCT01899001",
      "title": "Mood and Nutrition Interventions in Polycystic Ovary Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Polycystic Ovary Syndrome (PCOS)"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition Counseling",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2013-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-11-23",
      "last_synced_at": "2026-06-11T05:34:23.425Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01899001"
    }
  ]
}