{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Quality+of+Life&page=2",
    "query": {
      "condition": "Depression and Quality of Life",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depression+and+Quality+of+Life&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T18:00:00.112Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05563805",
      "title": "Exploring Virtual Reality Adventure Training Exergaming",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Activity",
        "Sedentary Behavior",
        "Depression",
        "Cognitive Function",
        "Post Traumatic Stress Disorder",
        "Quality of Life",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "Virtual Reality-based physical activity intervention",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas at Arlington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2022-09-07",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Arlington, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05563805"
    },
    {
      "nct_id": "NCT05187117",
      "title": "CAPABLE Family Pilot - Adapting CAPABLE for Older Adults With Mild Cognitive Impairment (MCI)/Early Stage Dementia and Their Care Partners",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia, Mild",
        "Mild Cognitive Impairment",
        "Disability Physical",
        "Impairment, Cognitive",
        "Caregiver Burden",
        "Quality of Life",
        "Depression"
      ],
      "interventions": [
        {
          "name": "CAPABLE Family - Open Label Pilot",
          "type": "BEHAVIORAL"
        },
        {
          "name": "CAPABLE Family - Randomized Control Trial",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "60 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2022-03-09",
      "completion_date": "2024-04-15",
      "has_results": false,
      "last_update_posted_date": "2024-04-17",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05187117"
    },
    {
      "nct_id": "NCT00298805",
      "title": "A Quality of Life Study in Patients With Migraines",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Migraine",
        "Headache",
        "Depression"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2006-01",
      "completion_date": "2013-04",
      "has_results": false,
      "last_update_posted_date": "2013-08-12",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Great Neck, New York",
      "locations": [
        {
          "city": "Great Neck",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00298805"
    },
    {
      "nct_id": "NCT06856057",
      "title": "Improving Behavioral Health for Caregivers and Children After Pediatric Injury",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Quality of Life",
        "PTSD",
        "Depression Not Otherwise Specified",
        "Child Externalizing Behavior"
      ],
      "interventions": [
        {
          "name": "Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 348,
      "start_date": "2025-05-28",
      "completion_date": "2028-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-07-10",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 4,
      "location_summary": "Los Angeles, California • Lexington, Kentucky • Ann Arbor, Michigan + 1 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Lexington",
          "state": "Kentucky"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06856057"
    },
    {
      "nct_id": "NCT05089201",
      "title": "A Pilot Study to Examine the Impact of a Therapy Dog Intervention on Loneliness and Related Health Outcomes in Vulnerable Populations",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Loneliness",
        "Depression",
        "Anxiety",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Animal-assisted interaction",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conversational control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 72,
      "start_date": "2021-11-16",
      "completion_date": "2024-01-31",
      "has_results": false,
      "last_update_posted_date": "2024-04-12",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05089201"
    },
    {
      "nct_id": "NCT02533804",
      "title": "The Lake Nona Life Project",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Health Behavior",
        "Quality of Life",
        "Aging"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Central Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "110 Years",
        "sex": "ALL",
        "summary": "18 Years to 110 Years"
      },
      "enrollment_count": 10000,
      "start_date": "2014-12-31",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02533804"
    },
    {
      "nct_id": "NCT06662409",
      "title": "Support for Bereaved Cancer Caregivers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bereavement",
        "Cancer",
        "Caregiver",
        "Grief"
      ],
      "interventions": [
        {
          "name": "Nature-based healing meditation (NBHM) intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-06-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-09-11",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "East Lansing, Michigan",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06662409"
    },
    {
      "nct_id": "NCT03168971",
      "title": "Managing Anxiety From Cancer (MAC): Testing an Intervention for Anxiety in Older Adults With Cancer and Their Caregivers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Depression",
        "Quality of Life"
      ],
      "interventions": [
        {
          "name": "Managing Anxiety from Cancer (MAC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2019-01-23",
      "completion_date": "2025-10-27",
      "has_results": false,
      "last_update_posted_date": "2025-10-29",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03168971"
    },
    {
      "nct_id": "NCT02988687",
      "title": "Metabolic and QOL Effects of GH Treatment in Patients With TBI and AGHD",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Adult-Onset Growth Hormone Deficiency"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Garcia, Jose M., MD, PhD",
      "sponsor_class": "INDIV",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 7,
      "start_date": "2016-11",
      "completion_date": "2022-10",
      "has_results": false,
      "last_update_posted_date": "2023-03-06",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02988687"
    },
    {
      "nct_id": "NCT01633008",
      "title": "Acceptance and Commitment Therapy for Adolescents and Young Adults With Neurofibromatosis and Chronic Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Neurofibromatosis"
      ],
      "interventions": [
        {
          "name": "ACT Workshop",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "12 Years to 99 Years"
      },
      "enrollment_count": 28,
      "start_date": "2012-06-15",
      "completion_date": "2017-01-10",
      "has_results": false,
      "last_update_posted_date": "2019-09-30",
      "last_synced_at": "2026-06-26T18:00:00.112Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01633008"
    }
  ]
}