{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depth+of+Focus",
    "query": {
      "condition": "Depth of Focus"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 22,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Depth+of+Focus&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T09:27:41.706Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07099950",
      "title": "Dose-Dependent Effects of Low-Intensity Focused Ultrasound",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy Controls"
      ],
      "interventions": [
        {
          "name": "Low-intensity focused ultrasound",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Laureate Institute for Brain Research, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 66,
      "start_date": "2025-04-22",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2025-10-16",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07099950"
    },
    {
      "nct_id": "NCT07800962",
      "title": "Federated Learning for Point-of-Care Cardiac Ultrasound",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ventricular Dysfunction, Left",
        "Ventricular Function, Left",
        "Echocardiography",
        "Ultrasonography",
        "Point-of-Care Systems",
        "Heart Function Tests",
        "Stroke Volume",
        "Federated Learning",
        "Machine Learning",
        "Artificial Intelligence (AI)",
        "Deep Learning",
        "Neural Networks, Computer",
        "Image Interpretation, Computer-Assisted",
        "Diagnosis, Computer-Assisted",
        "Sensitivity and Specificity",
        "ROC Curve"
      ],
      "interventions": [
        {
          "name": "Focused Cardiac Point-of-Care Ultrasonography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "FL-POCUS Federated Machine-Learning Analysis System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "Truway Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3000,
      "start_date": "2026-08-31",
      "completion_date": "2037-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-02",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07800962"
    },
    {
      "nct_id": "NCT03358862",
      "title": "Myopia Progression With a Novel Extended Depth of Focus Contact Lens",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myopia",
        "Myopia, Progressive"
      ],
      "interventions": [
        {
          "name": "NaturalVue Multifocal Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Aller, Thomas A., OD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "5 Years to 25 Years"
      },
      "enrollment_count": 80,
      "start_date": "2017-01-01",
      "completion_date": "2022-07-01",
      "has_results": false,
      "last_update_posted_date": "2021-01-12",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "San Bruno, California",
      "locations": [
        {
          "city": "San Bruno",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03358862"
    },
    {
      "nct_id": "NCT06567834",
      "title": "Clinical Evaluation and Comparison of the Tecnis Symfony Optiblue and Tecnis Symfony IOLs",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract",
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Tecnis Symfony Optiblue/Tecnis Symfony Optiblue Toric (Models ZXR00V/ZXW150)",
          "type": "DEVICE"
        },
        {
          "name": "Tecnis Symfony/Tecnis Symfony Toric (Models ZXR00/ZXT150)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Empire Eye and Laser Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2022-03-21",
      "completion_date": "2023-03-09",
      "has_results": false,
      "last_update_posted_date": "2024-08-23",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "Bakersfield, California",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06567834"
    },
    {
      "nct_id": "NCT06698731",
      "title": "A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia Condition"
      ],
      "interventions": [
        {
          "name": "Test lens",
          "type": "DEVICE"
        },
        {
          "name": "Control lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bruno Vision Care",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "45 Years to 70 Years"
      },
      "enrollment_count": 78,
      "start_date": "2024-10-28",
      "completion_date": "2025-01-15",
      "has_results": true,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 3,
      "location_summary": "Longwood, Florida • Pittsburg, Kansas • Warwick, Rhode Island",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Warwick",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06698731"
    },
    {
      "nct_id": "NCT02911103",
      "title": "Deep Brain Stimulation Surgery for Focal Hand Dystonia",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Dystonia",
        "Focal Dystonia",
        "Musician's Dystonia"
      ],
      "interventions": [
        {
          "name": "DBS surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Medtronic Activa Rechargeable System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "22 Years to 100 Years"
      },
      "enrollment_count": 5,
      "start_date": "2018-01-17",
      "completion_date": "2029-02-02",
      "has_results": false,
      "last_update_posted_date": "2026-08-28",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02911103"
    },
    {
      "nct_id": "NCT03633695",
      "title": "Clinical Evaluation of a Small Aperture Extended Depth of Focus Intraocular Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract",
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "IC-8 IOL Group",
          "type": "DEVICE"
        },
        {
          "name": "Control Group",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "AcuFocus, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 453,
      "start_date": "2018-12-04",
      "completion_date": "2020-10-15",
      "has_results": true,
      "last_update_posted_date": "2022-10-24",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 21,
      "location_summary": "Tucson, Arizona • Bakersfield, California • Laguna Hills, California + 18 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Laguna Hills",
          "state": "California"
        },
        {
          "city": "Los Altos",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03633695"
    },
    {
      "nct_id": "NCT03082599",
      "title": "Symfony Toric Intraocular Lens Visual Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract Bilateral",
        "Astigmatism Bilateral"
      ],
      "interventions": [
        {
          "name": "Presbyopia and astigmatism correcting intraocular lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Carolina Eyecare Physicians, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "40 Years to 99 Years"
      },
      "enrollment_count": 120,
      "start_date": "2017-02-17",
      "completion_date": "2018-04-03",
      "has_results": true,
      "last_update_posted_date": "2020-01-27",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 4,
      "location_summary": "Stillwater, Minnesota • Garden City, New York • Mt. Pleasant, South Carolina + 1 more",
      "locations": [
        {
          "city": "Stillwater",
          "state": "Minnesota"
        },
        {
          "city": "Garden City",
          "state": "New York"
        },
        {
          "city": "Mt. Pleasant",
          "state": "South Carolina"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03082599"
    },
    {
      "nct_id": "NCT04570579",
      "title": "Impact of a Novel Extended Depth of Focus Intraocular Lens on Visual and Lifestyle Enhancement",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cataract",
        "Cataract Senile",
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Vivity Extended Depth of Focus Intraocular Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alanna Nattis, DO",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2020-10-14",
      "completion_date": "2025-12-30",
      "has_results": false,
      "last_update_posted_date": "2025-05-14",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 1,
      "location_summary": "Babylon, New York",
      "locations": [
        {
          "city": "Babylon",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04570579"
    },
    {
      "nct_id": "NCT03274986",
      "title": "A Clinical Study of the ACRYSOF® IQ Extended Depth of Focus Intraocular Lens (IOL)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cataract"
      ],
      "interventions": [
        {
          "name": "ACRYSOF® IQ Extended Depth of Focus IOL",
          "type": "DEVICE"
        },
        {
          "name": "ACRYSOF® IQ Monofocal IOL",
          "type": "DEVICE"
        },
        {
          "name": "Cataract surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 242,
      "start_date": "2017-10-11",
      "completion_date": "2018-10-16",
      "has_results": true,
      "last_update_posted_date": "2020-04-07",
      "last_synced_at": "2026-09-04T09:27:41.706Z",
      "location_count": 11,
      "location_summary": "Birmingham, Alabama • Fort Collins, Colorado • Bradenton, Florida + 8 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Fort Collins",
          "state": "Colorado"
        },
        {
          "city": "Bradenton",
          "state": "Florida"
        },
        {
          "city": "Sebring",
          "state": "Florida"
        },
        {
          "city": "Gainesville",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03274986"
    }
  ]
}