{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Descending+Thoracic+Aortic+Disease",
    "query": {
      "condition": "Descending Thoracic Aortic Disease"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 17,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Descending+Thoracic+Aortic+Disease&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-24T12:52:22.033Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03440697",
      "title": "Pathogenetic Basis of Aortopathy and Aortic Valve Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Aortopathies",
        "Thoracic Aortic Aneurysm",
        "Aortic Valve Disease",
        "Thoracic Aortic Disease",
        "Thoracic Aortic Dissection",
        "Thoracic Aortic Rupture",
        "Ascending Aortic Disease",
        "Descending Aortic Disease",
        "Ascending Aortic Aneurysm",
        "Descending Aortic Aneurysm",
        "Marfan Syndrome",
        "Loeys-Dietz Syndrome",
        "Vascular Ehlers-Danlos Syndrome",
        "Shprintzen-Goldberg Syndrome",
        "Turner Syndrome",
        "PHACE Syndrome",
        "Autosomal Recessive Cutis Laxa",
        "Congenital Contractural Arachnodactyly",
        "Arterial Tortuosity Syndrome",
        "Bicuspid Aortic Valve-Associated Aortopathy",
        "Bicuspid Aortic Valve",
        "Familial Thoracic Aortic Aneurysm and Aortic Dissection"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 3000,
      "start_date": "2015-12-10",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-13",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia • Indianapolis, Indiana",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03440697"
    },
    {
      "nct_id": "NCT02777528",
      "title": "Evaluation of the GORE® TBE Device in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta, Zone 0/1",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic",
        "Aorta, Lesion"
      ],
      "interventions": [
        {
          "name": "GORE® TAG® Thoracic Branch Endoprosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Revascularization Procedure",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 79,
      "start_date": "2016-08",
      "completion_date": "2028-03",
      "has_results": true,
      "last_update_posted_date": "2025-06-25",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 34,
      "location_summary": "Los Angeles, California • Stanford, California • Hartford, Connecticut + 28 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02777528"
    },
    {
      "nct_id": "NCT00111176",
      "title": "STARZ-TX2 Clinical Study: Study of Thoracic Aortic Aneurysm Repair With the Zenith TX2 Endovascular Graft",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Aortic Aneurysm"
      ],
      "interventions": [
        {
          "name": "Endovascular repair",
          "type": "DEVICE"
        },
        {
          "name": "Surgical",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Cook Group Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 260,
      "start_date": "2004-03",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2014-08-18",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 38,
      "location_summary": "Mesa, Arizona • Phoenix, Arizona • San Francisco, California + 28 more",
      "locations": [
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00111176"
    },
    {
      "nct_id": "NCT00413231",
      "title": "Valor II: The Valiant Thoracic Stent Graft System Clinical Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thoracic Aortic Aneurysm"
      ],
      "interventions": [
        {
          "name": "Valiant Thoracic Stent Graft System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medtronic Cardiovascular",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 160,
      "start_date": "2006-12",
      "completion_date": "2014-10",
      "has_results": true,
      "last_update_posted_date": "2021-11-03",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 26,
      "location_summary": "Birmingham, Alabama • Los Angeles, California • Torrance, California + 21 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Torrance",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00413231"
    },
    {
      "nct_id": "NCT02777593",
      "title": "Evaluation of the GORE® TBE Device in the Treatment of Lesions of the Aortic Arch and Descending Thoracic Aorta, Zone 2",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic",
        "Aorta; Lesion"
      ],
      "interventions": [
        {
          "name": "GORE® TAG® Thoracic Branch Endoprosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 250,
      "start_date": "2016-09-06",
      "completion_date": "2027-12",
      "has_results": true,
      "last_update_posted_date": "2026-03-09",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 35,
      "location_summary": "Los Angeles, California • Stanford, California • Hartford, Connecticut + 29 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02777593"
    },
    {
      "nct_id": "NCT02043691",
      "title": "Evaluation of the Cook Custom Aortic Endograft, the Zenith t-Branch Endovascular Graft, and Surgeon-Modified Endograft in Treating Aortic Pathologies",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Juxtarenal Aortic Aneurysm",
        "Suprarenal Aortic Aneurysm",
        "Thoracoabdominal Aortic Aneurysm",
        "Penetrating Aortic Ulcer",
        "Aortic Arch Aneurysm",
        "Aortic Dissection"
      ],
      "interventions": [
        {
          "name": "Cook Custom Aortic Endograft",
          "type": "DEVICE"
        },
        {
          "name": "Zenith t-Branch Endovascular Graft",
          "type": "DEVICE"
        },
        {
          "name": "Surgeon-Modified Endograft",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 410,
      "start_date": "2014-06",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-01-06",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02043691"
    },
    {
      "nct_id": "NCT00802984",
      "title": "Endovascular Repair of Descending Thoracic Aortic Aneurysms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "Endovascular thoracic aortic aneurysm repair using TALENT TAA Stent Graft System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 29,
      "start_date": "2002-01",
      "completion_date": "2005-12",
      "has_results": false,
      "last_update_posted_date": "2020-10-08",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00802984"
    },
    {
      "nct_id": "NCT02021812",
      "title": "Feasibility Study for GORE® TAG® Thoracic Branch Endoprosthesis to Treat Proximal Descending Thoracic Aortic Aneurysms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "GORE® TAG® Thoracic Branch Endoprosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2014-01",
      "completion_date": "2022-03",
      "has_results": true,
      "last_update_posted_date": "2022-09-09",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 6,
      "location_summary": "Stanford, California • Ann Arbor, Michigan • Rochester, Minnesota + 3 more",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Lebanon",
          "state": "New Hampshire"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02021812"
    },
    {
      "nct_id": "NCT00590759",
      "title": "Evaluation of the GORE TAG Thoracic Endoprosthesis in the Treatment of Aneurysms",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aortic Aneurysm, Thoracic"
      ],
      "interventions": [
        {
          "name": "GORE TAG® Thoracic Endoprosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2005-08",
      "completion_date": "2013-04",
      "has_results": true,
      "last_update_posted_date": "2014-08-07",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 25,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • San Francisco, California + 22 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Greeley",
          "state": "Colorado"
        },
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00590759"
    },
    {
      "nct_id": "NCT00874250",
      "title": "Thoracic Endoprosthesis for Treatment of Aneurysm of the Descending Thoracic Aortic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aneurysm"
      ],
      "interventions": [
        {
          "name": "GORE CTAG Device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2009-06",
      "completion_date": "2017-01-06",
      "has_results": true,
      "last_update_posted_date": "2017-08-25",
      "last_synced_at": "2026-07-24T12:52:22.033Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00874250"
    }
  ]
}