{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Developmental+Defect&page=76", "query": { "condition": "Developmental Defect", "page": 76 }, "page_size": 10 }, "pagination": { "page": 76, "page_size": 10, "total_count": 10816, "total_pages": 1082, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Developmental+Defect&page=77&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Developmental+Defect&page=75&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-31T07:55:41.797Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02091141", "title": "My Pathway: A Study Evaluating Herceptin/Perjeta, Tarceva, Zelboraf/Cotellic, Erivedge, Alecensa, and Tecentriq Treatment Targeted Against Certain Molecular Alterations in Participants With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Neoplasms", "Solid Tumors", "Biliary Cancer", "Salivary Cancer", "Bladder Cancer" ], "interventions": [ { "name": "Trastuzumab", "type": "DRUG" }, { "name": "Pertuzumab", "type": "DRUG" }, { "name": "Erlotinib", "type": "DRUG" }, { "name": "Vemurafenib", "type": "DRUG" }, { "name": "Cobimetinib", "type": "DRUG" }, { "name": "Vismodegib", "type": "DRUG" }, { "name": "Alectinib", "type": "DRUG" }, { "name": "Atezolizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Genentech, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 673, "start_date": "2014-04-14", "completion_date": "2023-05-24", "has_results": true, "last_update_posted_date": "2024-07-23", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 60, "location_summary": "Goodyear, Arizona • Phoenix, Arizona • Springdale, Arkansas + 47 more", "locations": [ { "city": "Goodyear", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Springdale", "state": "Arkansas" }, { "city": "Culver City", "state": "California" }, { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02091141" }, { "nct_id": "NCT06366503", "title": "Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Photoaging", "Wrinkle", "Skin Laxity" ], "interventions": [ { "name": "Fractional Ablative CO2 Laser", "type": "PROCEDURE" }, { "name": "Facial Cleanser", "type": "OTHER" }, { "name": "Facial Moisturizer", "type": "OTHER" }, { "name": "Sunscreen", "type": "OTHER" }, { "name": "Basic Ointment", "type": "OTHER" } ], "intervention_types": [ "PROCEDURE", "OTHER" ], "sponsor": "Revision Skincare", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "35 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "35 Years to 65 Years · Female only" }, "enrollment_count": 23, "start_date": "2023-10-03", "completion_date": "2023-12-29", "has_results": false, "last_update_posted_date": "2025-08-03", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 1, "location_summary": "Blue Ash, Ohio", "locations": [ { "city": "Blue Ash", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT06366503" }, { "nct_id": "NCT00722254", "title": "Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Primary Myelofibrosis", "Primary Pulmonary Hypertension", "Secondary Myelofibrosis", "Pulmonary Arterial Hypertension" ], "interventions": [], "intervention_types": [], "sponsor": "University of Utah", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2006-06", "completion_date": "2009-02", "has_results": false, "last_update_posted_date": "2016-03-21", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 2, "location_summary": "Salt Lake City, Utah", "locations": [ { "city": "Salt Lake City", "state": "Utah" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00722254" }, { "nct_id": "NCT00000894", "title": "Comparison of Two Drugs, Cidofovir and Ganciclovir, in Treating Patients With AIDS Who Have CMV Retinitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Cytomegalovirus Retinitis", "HIV Infections" ], "interventions": [ { "name": "Cidofovir", "type": "DRUG" }, { "name": "Probenecid", "type": "DRUG" }, { "name": "Ganciclovir", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 300, "start_date": null, "completion_date": null, "has_results": false, "last_update_posted_date": "2011-02-23", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 12, "location_summary": "Los Angeles, California • Miami, Florida • Atlanta, Georgia + 7 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00000894" }, { "nct_id": "NCT04357951", "title": "D-cycloserine Augmented Treatment for Youth With Tic Disorders", "overall_status": "WITHDRAWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Tourette Syndrome" ], "interventions": [ { "name": "d-cycloserine", "type": "DRUG" }, { "name": "Placebo pill", "type": "DRUG" }, { "name": "Behavior Therapy", "type": "BEHAVIORAL" } ], "intervention_types": [ "DRUG", "BEHAVIORAL" ], "sponsor": "Johns Hopkins University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "8 Years to 17 Years" }, "enrollment_count": 0, "start_date": "2023-04-15", "completion_date": "2024-09", "has_results": false, "last_update_posted_date": "2023-04-14", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT04357951" }, { "nct_id": "NCT02624388", "title": "Study of Genistein in Pediatric Oncology Patients (UVA-Gen001)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Lymphoma", "Childhood Lymphoma", "Solid Tumor", "Childhood Solid Tumor", "Neuroblastoma", "Ewing Sarcoma", "Hodgkin Lymphoma", "Non-Hodgkin Lymphoma", "Rhabdomyosarcoma", "Soft Tissue Sarcoma", "Medulloblastoma", "Germ Cell Tumor", "Wilms Tumor", "Brain Neoplasms", "Medulloblastoma, Childhood", "Neuroectodermal Tumors, Primitive" ], "interventions": [ { "name": "Genistein", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Virginia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "21 Years", "sex": "ALL", "summary": "1 Year to 21 Years" }, "enrollment_count": 4, "start_date": "2016-08", "completion_date": "2021-09", "has_results": true, "last_update_posted_date": "2024-05-06", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 1, "location_summary": "Charlottesville, Virginia", "locations": [ { "city": "Charlottesville", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT02624388" }, { "nct_id": "NCT04397861", "title": "T Cell Memory Fuels the Innate Response in Chronic CF Lung Disease", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Cystic Fibrosis" ], "interventions": [], "intervention_types": [], "sponsor": "National Jewish Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 112, "start_date": "2015-05-06", "completion_date": "2021-11-01", "has_results": false, "last_update_posted_date": "2022-09-29", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 1, "location_summary": "Denver, Colorado", "locations": [ { "city": "Denver", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04397861" }, { "nct_id": "NCT01322269", "title": "A Study of HQK-1001 in Patients With Sickle Cell Disease", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Sickle Cell Disease", "Sickle Cell Anemia", "Sickle Cell Disorders", "Hemoglobin S Disease", "Sickling Disorder Due to Hemoglobin S" ], "interventions": [ { "name": "HQK-1001", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "HemaQuest Pharmaceuticals Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "12 Years to 60 Years" }, "enrollment_count": 52, "start_date": "2011-04", "completion_date": null, "has_results": false, "last_update_posted_date": "2013-06-19", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 9, "location_summary": "Oakland, California • Miami, Florida • Augusta, Georgia + 6 more", "locations": [ { "city": "Oakland", "state": "California" }, { "city": "Miami", "state": "Florida" }, { "city": "Augusta", "state": "Georgia" }, { "city": "Chicago", "state": "Illinois" }, { "city": "Shreveport", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01322269" }, { "nct_id": "NCT07425769", "title": "Adapting RDAD for DS", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Down Syndrome (DS)", "Alzheimer's Disease (AD)" ], "interventions": [ { "name": "Remote Exercise Sessions", "type": "BEHAVIORAL" }, { "name": "Caregiver Education Sessions", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Kansas Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 40, "start_date": "2026-03-31", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-08-03", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 1, "location_summary": "Kansas City, Kansas", "locations": [ { "city": "Kansas City", "state": "Kansas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07425769" }, { "nct_id": "NCT02135705", "title": "LOWER: Lomitapide Observational Worldwide Evaluation Registry", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Homozygous Familial Hypercholesterolemia" ], "interventions": [ { "name": "Lomitapide", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Amryt Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": null, "sex": "ALL", "summary": "Not listed" }, "enrollment_count": 260, "start_date": "2014-03-18", "completion_date": "2026-04-27", "has_results": false, "last_update_posted_date": "2026-05-12", "last_synced_at": "2026-10-31T07:55:41.797Z", "location_count": 46, "location_summary": "Birmingham, Alabama • Mobile, Alabama • Cottonwood, Arizona + 37 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Mobile", "state": "Alabama" }, { "city": "Cottonwood", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02135705" } ] }