{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetes+and+Heart+Failure&page=4",
    "query": {
      "condition": "Diabetes and Heart Failure",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 135,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetes+and+Heart+Failure&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetes+and+Heart+Failure&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T19:29:17.637Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06914141",
      "title": "Comparative Effectiveness of Tirzepatide Versus Semaglutide in Individuals With Heart Failure With Preserved Ejection Fraction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes Mellitus, Type 2",
        "HFpEF - Heart Failure With Preserved Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Tirzepatide",
          "type": "DRUG"
        },
        {
          "name": "Semaglutide",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 28118,
      "start_date": "2025-01-14",
      "completion_date": "2025-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06914141"
    },
    {
      "nct_id": "NCT05574699",
      "title": "Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Disease",
        "Diabetes Mellitus",
        "Hypertension",
        "Congestive Heart Failure"
      ],
      "interventions": [
        {
          "name": "Social Risk Score and CDS Tool",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 251,
      "start_date": "2023-04-30",
      "completion_date": "2025-05-27",
      "has_results": true,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 5,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05574699"
    },
    {
      "nct_id": "NCT04283994",
      "title": "Project to Improve Communication About Serious Illness--Hospital Study: Comparative Effectiveness Trial (Trial 2)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dementia",
        "Chronic Disease",
        "Neoplasm Metastasis",
        "Lung Neoplasms",
        "Pulmonary Disease, Chronic Obstructive",
        "Heart Failure, Congestive",
        "Liver Cirrhosis",
        "Kidney Failure, Chronic",
        "Lung Diseases, Interstitial",
        "Peripheral Vascular Disease",
        "Diabetes With End Organ Injury"
      ],
      "interventions": [
        {
          "name": "Survey-based Patient/Clinician Jumpstart",
          "type": "BEHAVIORAL"
        },
        {
          "name": "EHR-based Clinician Jumpstart",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 756,
      "start_date": "2021-07-26",
      "completion_date": "2025-01-27",
      "has_results": true,
      "last_update_posted_date": "2025-06-24",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 3,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        },
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04283994"
    },
    {
      "nct_id": "NCT04071626",
      "title": "Evaluating Metabolic Mechanisms of Ertugliflozin in Diabetes & Heart Failure",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure, Diastolic",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Ertugliflozin 5 mg",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University Hospitals Cleveland Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 9,
      "start_date": "2020-03-01",
      "completion_date": "2023-01-11",
      "has_results": true,
      "last_update_posted_date": "2023-12-13",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04071626"
    },
    {
      "nct_id": "NCT06583395",
      "title": "Quest to Analyze One Thousand Humans Meditating",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amyotrophic Lateral Sclerosis (ALS)",
        "Angina, Stable",
        "Anxiety",
        "Asthma",
        "Atrial Fibrillation",
        "Cancer Brain",
        "Cancer, Breast",
        "Cancer Colon",
        "Cancer, Lung",
        "Cancer, Ovarian",
        "Cancer Prostate",
        "Cancer Skin",
        "Throat Cancer",
        "Lymphoma",
        "Cancer, Thyroid",
        "Cancer, Other",
        "Cerebral Palsy",
        "Chronic Fatigue Syndrome",
        "Cluster Headache",
        "Chronic Obstructive Pulmonary Disease (COPD)",
        "Chronic Kidney Diseases",
        "Crohn Disease",
        "Deafness",
        "Depression",
        "Diabetes",
        "Eczema",
        "Epilepsy",
        "Fibroids",
        "Fibromyalgia",
        "Heart Failure",
        "Hypertension",
        "Hyperthyroidism",
        "Hypothyroidism",
        "Irritable Bowel Syndrome (IBS)",
        "Infertility",
        "Lyme Disease",
        "Macular Degeneration",
        "Migraine",
        "Multiple Allergies",
        "Multiple Sclerosis",
        "Osteoarthritis",
        "Osteoporosis",
        "Ovarian Cysts",
        "Parkinson Disease",
        "Phantom Limb Pain",
        "Psoriasis",
        "Post Traumatic Stress Disorder (PTSD)",
        "Rheumatoid Arthritis",
        "Sjogrens Disease",
        "Spinal Cord Injury",
        "Spinal Stenosis",
        "Stroke",
        "Tension Headache",
        "Tinnitus",
        "Ulcerative Colitis"
      ],
      "interventions": [
        {
          "name": "Advanced multi-component meditation practice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Tobias Moeller-Bertram",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 3000,
      "start_date": "2021-12-05",
      "completion_date": "2025-03-25",
      "has_results": false,
      "last_update_posted_date": "2024-11-01",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Palm Desert, California",
      "locations": [
        {
          "city": "Palm Desert",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06583395"
    },
    {
      "nct_id": "NCT01446705",
      "title": "Evaluation of VLER-Indiana Health Information Exchange Demonstration Project",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes Mellitus",
        "Asthma",
        "Cardiovascular Diseases",
        "Heart Failure",
        "Osteoporosis"
      ],
      "interventions": [
        {
          "name": "Active Health Information Exchange",
          "type": "OTHER"
        },
        {
          "name": "Non-Active Health Information exchange",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 57073,
      "start_date": "2012-12",
      "completion_date": "2016-01",
      "has_results": true,
      "last_update_posted_date": "2019-05-16",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01446705"
    },
    {
      "nct_id": "NCT07599293",
      "title": "Emulation of the EMPEROR-Preserved Trial Using Healthcare Claims Data",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure With Preserved Ejection Fraction",
        "Chronic Heart Failure",
        "Type 2 Diabetes Mellitus"
      ],
      "interventions": [
        {
          "name": "Empagliflozin",
          "type": "DRUG"
        },
        {
          "name": "Sitagliptin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39614,
      "start_date": "2024-10-13",
      "completion_date": "2026-06-19",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07599293"
    },
    {
      "nct_id": "NCT01014884",
      "title": "Coventry Outcomes Study of Seniors (COSS): A Comparative Effectiveness Study to Evaluate the Effect of a Multidisciplinary Team's Intervention on the Incidence of Nonelective Hospitalizations in a Medicare Population",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Chronic Obstructive Pulmonary Disease",
        "Cardiovascular Disease",
        "Diabetes",
        "Osteoporosis"
      ],
      "interventions": [
        {
          "name": "Multidisciplinary team interventions",
          "type": "OTHER"
        },
        {
          "name": "Multidisciplinary team bimonthly visits either in person or via telephone.",
          "type": "OTHER"
        },
        {
          "name": "Usual case management and pharmacy management as provided by the health Plan and the pharmacy benefit manager",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Medco Health Solutions, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 2150,
      "start_date": "2009-11",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2010-01-21",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 2,
      "location_summary": "Kansas City, Missouri • St Louis, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01014884"
    },
    {
      "nct_id": "NCT04083339",
      "title": "Safety and Efficacy of AT-001 in Patients With Diabetic Cardiomyopathy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diabetic Cardiomyopathies"
      ],
      "interventions": [
        {
          "name": "AT-001",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Applied Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 675,
      "start_date": "2019-09-20",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2022-12-08",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 28,
      "location_summary": "Beverly Hills, California • La Jolla, California • Lincoln, California + 20 more",
      "locations": [
        {
          "city": "Beverly Hills",
          "state": "California"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "Lincoln",
          "state": "California"
        },
        {
          "city": "Orange",
          "state": "California"
        },
        {
          "city": "Tarzana",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04083339"
    },
    {
      "nct_id": "NCT00344903",
      "title": "Dallas Heart Study 2: Return Clinic Visit for the Dallas Heart Study Cohort",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atherosclerosis",
        "Congestive Heart Failure",
        "Left Ventricular Hypertrophy",
        "Diabetes Mellitus",
        "Hypertension",
        "Obesity",
        "Metabolic Syndrome X",
        "Myocardial Infarction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "35 Years to 70 Years"
      },
      "enrollment_count": 3400,
      "start_date": "2007-09",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-07-08",
      "last_synced_at": "2026-10-06T19:29:17.637Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00344903"
    }
  ]
}