{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetic+Foot+Ulcer+%28DFU%29",
    "query": {
      "condition": "Diabetic Foot Ulcer (DFU)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 90,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetic+Foot+Ulcer+%28DFU%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:46:00.407Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07116174",
      "title": "A Prospective Clinical Study to Evaluate the Effectiveness and Safety of Xcell Amnio MatrixTM (XAM) in the Management of Chronic Non-healing DFUs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)"
      ],
      "interventions": [
        {
          "name": "Xcell Amnio Matrix",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Standard of Care (SOC)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "New Horizon Medical Solutions",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 135,
      "start_date": "2025-08-15",
      "completion_date": "2026-08-15",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 3,
      "location_summary": "Fresno, California • San Diego, California • Dallas, Texas",
      "locations": [
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07116174"
    },
    {
      "nct_id": "NCT06560502",
      "title": "Modified Multi-Platform Trial Assessing Multiple CAMPs and SOC vs SOC Alone in the Treatment of DFU and VLUs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer",
        "Ulcer Foot",
        "Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Standard of Care-DFU",
          "type": "OTHER"
        },
        {
          "name": "AmnioCore - DFU",
          "type": "OTHER"
        },
        {
          "name": "Amnio Quad-Core - DFU",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care-VLU",
          "type": "OTHER"
        },
        {
          "name": "Amnio Tri-Core - VLU",
          "type": "OTHER"
        },
        {
          "name": "Amniocore Pro +",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stability Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 324,
      "start_date": "2024-08-01",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-01-20",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 1,
      "location_summary": "Circleville, Ohio",
      "locations": [
        {
          "city": "Circleville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06560502"
    },
    {
      "nct_id": "NCT02581488",
      "title": "Use of Santyl in Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot",
        "Foot Ulcer, Diabetic"
      ],
      "interventions": [
        {
          "name": "Santyl",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Product containing silver",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Smith & Nephew, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 102,
      "start_date": "2015-10",
      "completion_date": "2017-01-12",
      "has_results": true,
      "last_update_posted_date": "2018-08-01",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 11,
      "location_summary": "Sylmar, California • Melbourne, Florida • Baltimore, Maryland + 8 more",
      "locations": [
        {
          "city": "Sylmar",
          "state": "California"
        },
        {
          "city": "Melbourne",
          "state": "Florida"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02581488"
    },
    {
      "nct_id": "NCT01596920",
      "title": "Grafix® DFU: Open-Label Extension Option to Evaluate Safety & Efficacy of Grafix® for Chronic Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "Tissue",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Osiris Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 97,
      "start_date": "2012-04",
      "completion_date": "2014-03",
      "has_results": false,
      "last_update_posted_date": "2014-04-09",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 15,
      "location_summary": "Montgomery, Alabama • Glendale, Arizona • Encinitas, California + 12 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Encinitas",
          "state": "California"
        },
        {
          "city": "Inverness",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01596920"
    },
    {
      "nct_id": "NCT07089602",
      "title": "Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot",
        "DFU",
        "Diabetic Foot Ulcer",
        "Foot Ulcer, Diabetic",
        "Ulcer Foot",
        "Venous Leg Ulcer",
        "Leg Ulcer",
        "Leg Ulcers Venous",
        "Ulcer"
      ],
      "interventions": [
        {
          "name": "Standard of Care DFU",
          "type": "OTHER"
        },
        {
          "name": "Tri-Membrane Wrap™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Lite™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Hydro™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care VLU",
          "type": "OTHER"
        },
        {
          "name": "Tri-Membrane Wrap™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Lite™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Hydro™ VLU",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "BioLab Holdings",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 650,
      "start_date": "2025-07-15",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 1,
      "location_summary": "Philidelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philidelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07089602"
    },
    {
      "nct_id": "NCT07498218",
      "title": "Phase 1 Study of VELGRAFT, a Living Cellular Construct, in the Management of Chronic Diabetic Foot Ulcers Which Have Attained Granulation Tissue",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Granulation of Chronic Diabetic Wounds"
      ],
      "interventions": [
        {
          "name": "an allogenic cell-based product, containing living human bone marrow-derived mesenchymal stem cells (MSCs) and MSCs differentiated into adipocytes on a porous chitosan-gelatin matrix",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care of Diabetic Foot Ulcers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Ayu, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 24,
      "start_date": "2026-03-11",
      "completion_date": "2026-10-13",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07498218"
    },
    {
      "nct_id": "NCT07223515",
      "title": "HEAL-4: Real-World Effectiveness of 4 Amniotic Allografts Adjunctive to Standard Care in DFU, VLU, and PU",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Venous Leg Ulcers (VLUs)",
        "Pressure Ulcers, Bedsores, Decubitus Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Dynamic Medical Services dba Acesso Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2000,
      "start_date": "2025-10-24",
      "completion_date": "2025-11",
      "has_results": false,
      "last_update_posted_date": "2025-11-03",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 2,
      "location_summary": "Novi, Michigan • Murfreesboro, Tennessee",
      "locations": [
        {
          "city": "Novi",
          "state": "Michigan"
        },
        {
          "city": "Murfreesboro",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223515"
    },
    {
      "nct_id": "NCT07086443",
      "title": "Randomized Evaluation of Nonhealing Diabetic Foot Ulcers With Exclusive Wound Therapy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "DFU",
        "Diabetic Foot Ulcer (DFU)",
        "Foot Ulcer Due to Type 1 Diabetes Mellitus",
        "Foot Ulcer Due to Type 2 Diabetes Mellitus",
        "Ulcer",
        "Ulcer Foot"
      ],
      "interventions": [
        {
          "name": "Activate™ Matrix",
          "type": "OTHER"
        },
        {
          "name": "AmnioDefend™ FT Matrix",
          "type": "OTHER"
        },
        {
          "name": "Palisade™ DM Matrix",
          "type": "OTHER"
        },
        {
          "name": "Enclose™ TL Matrix",
          "type": "OTHER"
        },
        {
          "name": "Sentry™ SL Matrix",
          "type": "OTHER"
        },
        {
          "name": "Shelter™ DM Matrix + SOC",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sequence LifeScience, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 350,
      "start_date": "2025-07-11",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-19",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 1,
      "location_summary": "Monroeville, Pennsylvania",
      "locations": [
        {
          "city": "Monroeville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07086443"
    },
    {
      "nct_id": "NCT02260609",
      "title": "GrafixCORE®: Open-Label Study to Evaluate the Safety and Efficacy of GrafixCORE® for Complex Diabetic Foot Wounds",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Complex Diabetic Foot Wounds"
      ],
      "interventions": [
        {
          "name": "Grafix®",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Osiris Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 31,
      "start_date": "2014-10",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2016-02-02",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 4,
      "location_summary": "Phoenix, Arizona • Tucson, Arizona • Miami, Florida + 1 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Weymouth",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02260609"
    },
    {
      "nct_id": "NCT04817228",
      "title": "A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Venous Leg Ulcer",
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "EscharEx (EX-02 formulation)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "MediWound Ltd",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 12,
      "start_date": "2021-04-21",
      "completion_date": "2022-05-20",
      "has_results": false,
      "last_update_posted_date": "2022-07-26",
      "last_synced_at": "2026-06-11T04:46:00.407Z",
      "location_count": 3,
      "location_summary": "Tamarac, Florida • Las Vegas, Nevada • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Tamarac",
          "state": "Florida"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04817228"
    }
  ]
}