{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetic+Lower+Extremity+Ulcers",
    "query": {
      "condition": "Diabetic Lower Extremity Ulcers"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 379,
    "total_pages": 38,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diabetic+Lower+Extremity+Ulcers&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-26T20:14:15.556Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02506452",
      "title": "Postmarket Study to Evaluate Biovance® in Diabetic Foot Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "Biovance®",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care, Diabetic Foot Ulcers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alliqua BioMedical, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 51,
      "start_date": "2015-06",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2017-05-17",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 10,
      "location_summary": "Montgomery, Alabama • Phoenix, Arizona • Fresno, California + 7 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02506452"
    },
    {
      "nct_id": "NCT07444593",
      "title": "Transverse Tibial Bone Transport (TTT) in the Management of Chronic Diabetic Lower Extremity Wounds",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Chronic Ulcers of the Lower Limb"
      ],
      "interventions": [
        {
          "name": "Biodynamik XT3",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Biodynamik, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-05-01",
      "completion_date": "2027-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-04-27",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 1,
      "location_summary": "Jacksonville, Florida",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07444593"
    },
    {
      "nct_id": "NCT07172893",
      "title": "A Non-Randomized Open Label Clinical Trial Evaluating DermaBind TL",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Venous Leg Ulcer (VLU)"
      ],
      "interventions": [
        {
          "name": "DermaBind TL",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "HealthTech Wound Care",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 150,
      "start_date": "2025-12-10",
      "completion_date": "2027-05-21",
      "has_results": false,
      "last_update_posted_date": "2025-12-23",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 10,
      "location_summary": "DeLand, Florida • Palm Beach Gardens, Florida • Sweetwater, Florida + 7 more",
      "locations": [
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "Palm Beach Gardens",
          "state": "Florida"
        },
        {
          "city": "Sweetwater",
          "state": "Florida"
        },
        {
          "city": "Bloomfield Township",
          "state": "Michigan"
        },
        {
          "city": "Cary",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07172893"
    },
    {
      "nct_id": "NCT04040426",
      "title": "Bioactive Split Thickness Skin Allograft Versus Standard of Care in the Treatment of Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot",
        "Ulcer Foot"
      ],
      "interventions": [
        {
          "name": "Human split thickness skin allograft",
          "type": "OTHER"
        },
        {
          "name": "Additional Outer Dressing Applicaiton",
          "type": "OTHER"
        },
        {
          "name": "Offloading",
          "type": "OTHER"
        },
        {
          "name": "Fibracol Wound Dressing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Professional Education and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2019-08-06",
      "completion_date": "2021-10-01",
      "has_results": false,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 5,
      "location_summary": "San Francisco, California • O'Fallon, Illinois • Youngstown, Ohio + 2 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "O'Fallon",
          "state": "Illinois"
        },
        {
          "city": "Youngstown",
          "state": "Ohio"
        },
        {
          "city": "Martinsville",
          "state": "Virginia"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04040426"
    },
    {
      "nct_id": "NCT01154374",
      "title": "A Clinical Study of the Safety and Efficacy of MEBO® Wound Ointment in Subjects With Diabetic Foot Ulcers (Pilot)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcers"
      ],
      "interventions": [
        {
          "name": "MEBO Wound Ointment",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care (sterile saline moistened gauze)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Skingenix, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 7,
      "start_date": "2010-11",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2025-11-06",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 2,
      "location_summary": "New Haven, Connecticut • Boston, Massachusetts",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01154374"
    },
    {
      "nct_id": "NCT04198441",
      "title": "The Omeza Protocol for Chronic Ulcers",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Venous Leg Ulcer",
        "Diabetic Foot Ulcer"
      ],
      "interventions": [
        {
          "name": "Wound dressing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Omeza, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 78,
      "start_date": "2020-06-02",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-04-09",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Newark, New Jersey • Portland, Oregon + 1 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Newark",
          "state": "New Jersey"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04198441"
    },
    {
      "nct_id": "NCT03854695",
      "title": "Study to Evaluate Bacterial Activity That Drives the Progression of Clinical Infection",
      "overall_status": "WITHDRAWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2019-02-01",
      "completion_date": "2024-06-01",
      "has_results": false,
      "last_update_posted_date": "2019-02-26",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03854695"
    },
    {
      "nct_id": "NCT07209475",
      "title": "Effect of Amnio-Maxx on the Healing Rate of Chronic Diabetic Foot Ulcers.",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Amnio-Maxx"
      ],
      "interventions": [
        {
          "name": "Amnio-Maxx® Dual Layer Amnion Patch",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Standard of Care (Investigator Choice)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "Royal Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 248,
      "start_date": "2025-08-14",
      "completion_date": "2026-08-14",
      "has_results": false,
      "last_update_posted_date": "2025-10-07",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 8,
      "location_summary": "Burbank, California • Miami, Florida • Stone Mountain, Georgia + 5 more",
      "locations": [
        {
          "city": "Burbank",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Stone Mountain",
          "state": "Georgia"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "East Patchogue",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07209475"
    },
    {
      "nct_id": "NCT02119754",
      "title": "Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Infection"
      ],
      "interventions": [
        {
          "name": "Plurogel PN",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "PluroGen Therapeutics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2013-10",
      "completion_date": "2014-09",
      "has_results": false,
      "last_update_posted_date": "2014-09-25",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 15,
      "location_summary": "Phoenix, Arizona • Los Angeles, California • Oakland, California + 8 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Hamden",
          "state": "Connecticut"
        },
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02119754"
    },
    {
      "nct_id": "NCT02467998",
      "title": "Negative Pressure Wound Therapy Registry",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcers",
        "Venous Stasis Ulcer",
        "Pressure Ulcer",
        "Surgical Wound Dehiscence",
        "Burns",
        "Other Types of Chronic Non Healing Wounds"
      ],
      "interventions": [
        {
          "name": "NPWT",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "U.S. Wound Registry",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 50000,
      "start_date": "2005-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2018-05-01",
      "last_synced_at": "2026-06-26T20:14:15.556Z",
      "location_count": 1,
      "location_summary": "The Woodlands, Texas",
      "locations": [
        {
          "city": "The Woodlands",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02467998"
    }
  ]
}