{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diastolic+Dysfunction&page=2",
    "query": {
      "condition": "Diastolic Dysfunction",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diastolic+Dysfunction&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T04:11:34.388Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02860156",
      "title": "Characterizing HIV-related Diastolic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure",
        "HIV",
        "Diastolic Dysfunction"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 195,
      "start_date": "2016-11-15",
      "completion_date": "2018-02-09",
      "has_results": false,
      "last_update_posted_date": "2019-03-04",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 12,
      "location_summary": "Atlanta, Georgia • Chicago, Illinois • Boston, Massachusetts + 6 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02860156"
    },
    {
      "nct_id": "NCT03448185",
      "title": "Improving Metabolic Health in Patients With Diastolic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obesity",
        "Heart Failure, Diastolic",
        "Metabolic Syndrome"
      ],
      "interventions": [
        {
          "name": "High intensity exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Omega-3 fish oil",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Yoga",
          "type": "BEHAVIORAL"
        },
        {
          "name": "olive oil capsules",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "40 Years to 60 Years"
      },
      "enrollment_count": 80,
      "start_date": "2015-06-01",
      "completion_date": "2019-07-01",
      "has_results": true,
      "last_update_posted_date": "2023-01-05",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03448185"
    },
    {
      "nct_id": "NCT00068159",
      "title": "Cardiac Function in Patients With Hereditary Hemochromatosis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Hereditary Hemochromatosis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 70,
      "start_date": "2003-12-08",
      "completion_date": "2022-07-06",
      "has_results": false,
      "last_update_posted_date": "2024-05-03",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00068159"
    },
    {
      "nct_id": "NCT01052428",
      "title": "Molecular Mechanisms of Volume Overload-Aim 1(SCCOR in Cardiac Dysfunction and Disease)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Mitral Regurgitation"
      ],
      "interventions": [
        {
          "name": "metoprolol succinate (Toprol XL)",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "19 Years to 70 Years"
      },
      "enrollment_count": 38,
      "start_date": "2004-08",
      "completion_date": "2010-07",
      "has_results": true,
      "last_update_posted_date": "2012-11-22",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01052428"
    },
    {
      "nct_id": "NCT03826160",
      "title": "Growth Hormone Dynamics and Cardiac Steatosis in HIV",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Lipodystrophy",
        "Cardiac Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 23,
      "start_date": "2019-01-30",
      "completion_date": "2022-04-19",
      "has_results": false,
      "last_update_posted_date": "2022-07-19",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03826160"
    },
    {
      "nct_id": "NCT05058833",
      "title": "Prognostic Impact of Cardiac Diastolic Function and Coronary Microvascular Function",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemic Heart Disease",
        "Microvascular Coronary Artery Disease",
        "Diastolic Dysfunction",
        "Heart Failure With Preserved Ejection Fraction"
      ],
      "interventions": [
        {
          "name": "Echocardiography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Coronary flow reserve and index of microcirculatory dysfunction",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Samsung Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 800,
      "start_date": "2016-04-08",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-03-14",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05058833"
    },
    {
      "nct_id": "NCT00113152",
      "title": "Heart Disease in Sickle Cell Anemia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sickle Cell Anemia",
        "Pulmonary Hypertension"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institutes of Health Clinical Center (CC)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 120,
      "start_date": "2005-06-02",
      "completion_date": "2007-10-02",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00113152"
    },
    {
      "nct_id": "NCT01780727",
      "title": "Echo-guided Hemodynamic Management Strategy in Elderly Patients Undergoing Noncardiac Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventricular Dysfunction, Left",
        "Major Adverse Cardiac Events"
      ],
      "interventions": [
        {
          "name": "EGHEM",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "70 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "70 Years and older"
      },
      "enrollment_count": 97,
      "start_date": "2014-09-01",
      "completion_date": "2018-08-27",
      "has_results": false,
      "last_update_posted_date": "2023-09-15",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01780727"
    },
    {
      "nct_id": "NCT00684060",
      "title": "Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Left Ventricular Dysfunction"
      ],
      "interventions": [
        {
          "name": "Adult stem cells",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 87,
      "start_date": "2008-07",
      "completion_date": "2012-02",
      "has_results": true,
      "last_update_posted_date": "2015-07-10",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 5,
      "location_summary": "Gainesville, Florida • Minneapolis, Minnesota • Cleveland, Ohio + 2 more",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00684060"
    },
    {
      "nct_id": "NCT04177225",
      "title": "Effect of Diastolic Dysfunction on Dynamic Cardiac Monitors",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke Volume Variation",
        "Diastolic Dysfunction"
      ],
      "interventions": [
        {
          "name": "Trans thoracic Ultrasound Examination",
          "type": "PROCEDURE"
        },
        {
          "name": "Intravenous fluid administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2019-02-07",
      "completion_date": "2021-02-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-12",
      "last_synced_at": "2026-06-11T04:11:34.388Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04177225"
    }
  ]
}