{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Difficult+Intravenous+Access",
    "query": {
      "condition": "Difficult Intravenous Access"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 13,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Difficult+Intravenous+Access&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T04:49:00.569Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03591016",
      "title": "Prospective Observational Study of Difficult Intravenous Access in the Operating Room",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Difficult Intravenous Access"
      ],
      "interventions": [
        {
          "name": "Recording number of IV attempts",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ralph Beltran",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 1000,
      "start_date": "2018-07-02",
      "completion_date": "2020-12-08",
      "has_results": false,
      "last_update_posted_date": "2021-02-15",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03591016"
    },
    {
      "nct_id": "NCT00740727",
      "title": "EASI Access II --- Follow-up Study to the EASI Access Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Disaster Medicine",
        "Difficult Intravenous Access",
        "Dehydration"
      ],
      "interventions": [
        {
          "name": "Human recombinant hyaluronidase (HRH)",
          "type": "DRUG"
        },
        {
          "name": "Enzymatically Augmented Subcutaneous Infusion (EASI) line placement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2009-02",
      "completion_date": "2009-03",
      "has_results": true,
      "last_update_posted_date": "2009-09-11",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00740727"
    },
    {
      "nct_id": "NCT00692549",
      "title": "Ultrasound Guidance for Intravenous Cannulation in Emergency Department Patients.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Difficult IV Access"
      ],
      "interventions": [
        {
          "name": "ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2005-06",
      "completion_date": "2005-08",
      "has_results": false,
      "last_update_posted_date": "2008-06-06",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00692549"
    },
    {
      "nct_id": "NCT02125552",
      "title": "Ultrasound Guided IV Access in a Pediatric Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Difficult Intravenous Access in Pediatrics"
      ],
      "interventions": [
        {
          "name": "Ultrasound guidance",
          "type": "PROCEDURE"
        },
        {
          "name": "Traditional intravenous access",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 163,
      "start_date": "2014-05",
      "completion_date": "2017-03",
      "has_results": false,
      "last_update_posted_date": "2018-05-15",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02125552"
    },
    {
      "nct_id": "NCT01439113",
      "title": "Single-operator Ultrasound-guided IV Placement by Emergency Nurses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intravenous Infusions"
      ],
      "interventions": [
        {
          "name": "Ultrasound guided IV placement",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 50,
      "start_date": "2010-06",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2023-03-28",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Springfield, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Springfield",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01439113"
    },
    {
      "nct_id": "NCT00357799",
      "title": "VeinViewer for Peripheral IV Placement in Children With Difficult Intravenous (IV) Access",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Catheterization, Peripheral",
        "Phlebotomy"
      ],
      "interventions": [
        {
          "name": "VeinViewer",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Children's Hospital and Health System Foundation, Wisconsin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "Up to 19 Years"
      },
      "enrollment_count": 170,
      "start_date": "2006-10",
      "completion_date": "2010-10",
      "has_results": false,
      "last_update_posted_date": "2011-08-24",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00357799"
    },
    {
      "nct_id": "NCT00935909",
      "title": "Use of Vein Viewer for Insertion of Peripheral Venous Cannula in Pediatric Patients With Difficult Intravenous Access",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "IV Cannulation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Peter Szmuk",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "Up to 18 Years"
      },
      "enrollment_count": 603,
      "start_date": "2009-01",
      "completion_date": "2010-07",
      "has_results": false,
      "last_update_posted_date": "2013-06-21",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00935909"
    },
    {
      "nct_id": "NCT01676350",
      "title": "Intraosseous Access in the Emergency Department for Patients With Failed Attempts at Intravenous Access: A Randomized Trial Examining Resource Utilization and Patient Satisfaction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Difficult Peripheral IV Access"
      ],
      "interventions": [
        {
          "name": "IO access using EZ-IO®",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "WellSpan Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2014-08",
      "completion_date": "2015-06",
      "has_results": true,
      "last_update_posted_date": "2022-03-23",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 2,
      "location_summary": "Philadelphia, Pennsylvania • York, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "York",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01676350"
    },
    {
      "nct_id": "NCT01929304",
      "title": "Difficult Intravenous Access Perception: Difficult IV Access - Assessment of Patient Understanding",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Understanding Emergency Room Procedures"
      ],
      "interventions": [
        {
          "name": "Survey",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 1180,
      "start_date": "2013-08",
      "completion_date": "2016-07",
      "has_results": false,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01929304"
    },
    {
      "nct_id": "NCT03181542",
      "title": "Infra Red Vein Visualization: Efficacy vs. Standard Technique",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Difficult Intravenous Access"
      ],
      "interventions": [
        {
          "name": "Infrared illumination",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "2 Years",
        "sex": "ALL",
        "summary": "Up to 2 Years"
      },
      "enrollment_count": 160,
      "start_date": "2017-07-10",
      "completion_date": "2020-10-29",
      "has_results": true,
      "last_update_posted_date": "2021-12-21",
      "last_synced_at": "2026-05-22T04:49:00.569Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03181542"
    }
  ]
}