{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Digestive+Signs+and+Symptoms&page=27",
    "query": {
      "condition": "Digestive Signs and Symptoms",
      "page": 27
    },
    "page_size": 10
  },
  "pagination": {
    "page": 27,
    "page_size": 10,
    "total_count": 4667,
    "total_pages": 467,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Digestive+Signs+and+Symptoms&page=28&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Digestive+Signs+and+Symptoms&page=26&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-15T12:09:54.287Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07730853",
      "title": "Isocaloric Navy-Bean Substitution in Adults With MASLD",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)",
        "Liver Fibrosis",
        "Metabolic Dysfunction-Associated Steatohepatitis (MASH)"
      ],
      "interventions": [
        {
          "name": "Dietary Supplement/Behavioral: Navy Bean-Rich Diet",
          "type": "OTHER"
        },
        {
          "name": "Habitual Diet (Control)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2026-09-01",
      "completion_date": "2029-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-12",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07730853"
    },
    {
      "nct_id": "NCT04027972",
      "title": "Pharmacokinetics of Neostigmine and Glycopyrrolate",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Spinal Cord Injuries",
        "Constipation",
        "Fecal Incontinence",
        "Neurogenic Bowel"
      ],
      "interventions": [
        {
          "name": "Combination of Neostigmine and Glycopyrrolate",
          "type": "DRUG"
        },
        {
          "name": "I-Box by Dynatronics",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 13,
      "start_date": "2020-03-09",
      "completion_date": "2022-12-20",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04027972"
    },
    {
      "nct_id": "NCT05235204",
      "title": "Early Foley Catheter Removal After Diverticular Colovesical Fistula Repair",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Colovesical Fistula"
      ],
      "interventions": [
        {
          "name": "Removal of Foley Catheter 2 to 3 days post Colovesical Fistula (CVF) repair surgery",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Karim Alavi",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2019-03-13",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-20",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "Worcester, Massachusetts",
      "locations": [
        {
          "city": "Worcester",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05235204"
    },
    {
      "nct_id": "NCT02383758",
      "title": "An Interdisciplinary Approach to the Treatment of Encopresis in Children With Autism Spectrum Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Encopresis",
        "Autistic Disorder"
      ],
      "interventions": [
        {
          "name": "Glycerin Suppository",
          "type": "DRUG"
        },
        {
          "name": "Bisacodyl suppository",
          "type": "DRUG"
        },
        {
          "name": "Senna",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "5 Years to 21 Years"
      },
      "enrollment_count": 22,
      "start_date": "2015-02-01",
      "completion_date": "2017-01-01",
      "has_results": true,
      "last_update_posted_date": "2018-07-02",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02383758"
    },
    {
      "nct_id": "NCT01385956",
      "title": "SOM 230 and Gemcitabine in Advanced Pancreatic Cancer",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "SOM 230 LAR",
          "type": "DRUG"
        },
        {
          "name": "Gemcitabine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-06",
      "completion_date": "2014-11",
      "has_results": false,
      "last_update_posted_date": "2020-09-28",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01385956"
    },
    {
      "nct_id": "NCT07099131",
      "title": "Effective Interventions to Overcome Severe Gag Reflex",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Gagging"
      ],
      "interventions": [
        {
          "name": "Anesthetic spray",
          "type": "DRUG"
        },
        {
          "name": "Acupuncture",
          "type": "DEVICE"
        },
        {
          "name": "Masking Tape",
          "type": "GENETIC"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "GENETIC"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2025-12-07",
      "completion_date": "2028-12-07",
      "has_results": false,
      "last_update_posted_date": "2025-08-01",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07099131"
    },
    {
      "nct_id": "NCT00441337",
      "title": "A Study of MDX-1106 in Patients With Selected Refractory or Relapsed Malignancies",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Carcinoma, Non-Small-Cell Lung",
        "Colorectal Cancer",
        "Malignant Melanoma",
        "Renal Cancer",
        "Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "MDX-1106",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Bristol-Myers Squibb",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 39,
      "start_date": "2006-08",
      "completion_date": "2009-11",
      "has_results": true,
      "last_update_posted_date": "2015-02-20",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 4,
      "location_summary": "Baltimore, Maryland • Detroit, Michigan • St Louis, Missouri + 1 more",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Huntersville",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00441337"
    },
    {
      "nct_id": "NCT04306939",
      "title": "Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study",
      "overall_status": "SUSPENDED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Pancreatitis",
        "Inflammatory Bowel Diseases",
        "Hepatitis",
        "NASH - Nonalcoholic Steatohepatitis",
        "Acute Pancreatitis",
        "Rheumatoid Arthritis",
        "Diabetes Mellitus",
        "Dyslipidemias",
        "Multiple Sclerosis",
        "Irritable Bowel Syndrome",
        "Chronic Pain",
        "Chronic Disease",
        "Chronic Kidney Diseases",
        "Crohn Disease",
        "Celiac Disease",
        "Biliary Cirrhosis",
        "Bile Acid Synthesis Defect",
        "Gastritis",
        "Cholecystitis",
        "Cholelithiases",
        "IPMN",
        "Cyst Pancreas",
        "Cystic Fibrosis",
        "Pancreatic Exocrine Insufficiency",
        "Diarrhea Chronic",
        "Constipation - Functional",
        "Constipation Chronic Idiopathic"
      ],
      "interventions": [
        {
          "name": "venipuncture",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Additional Sample Collections",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 120000,
      "start_date": "2014-11-01",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-01-07",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04306939"
    },
    {
      "nct_id": "NCT05939947",
      "title": "A Clinical Trial of ALE.F02 in Patients With Advanced Liver Fibrosis and/or With Mild Cirrhosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Advanced Liver Fibrosis",
        "Liver Cirrhosis"
      ],
      "interventions": [
        {
          "name": "ALE.F02",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alentis Therapeutics AG",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 41,
      "start_date": "2023-04-01",
      "completion_date": "2024-10-30",
      "has_results": false,
      "last_update_posted_date": "2024-12-03",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "San Antonio, Texas",
      "locations": [
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05939947"
    },
    {
      "nct_id": "NCT00537758",
      "title": "Treatment for Obesity and Binge Eating Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Binge Eating Disorder",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavior Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "CBT and BWL",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Behavioral Weight Loss Treatment",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 125,
      "start_date": "2002-07",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2020-03-31",
      "last_synced_at": "2026-10-15T12:09:54.287Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00537758"
    }
  ]
}