{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diminished+Pleasure&page=2",
    "query": {
      "condition": "Diminished Pleasure",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diminished+Pleasure&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T01:20:44.559Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05223842",
      "title": "Family Promoting Positive Emotions Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Depression",
        "Anhedonia",
        "Stress",
        "Depressive Disorder",
        "Behavioral Symptoms",
        "Mood Disorders",
        "Mental Disorder",
        "Mood Disturbance"
      ],
      "interventions": [
        {
          "name": "Family Promoting Positive Emotions (F-PPE)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Written Information",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 74,
      "start_date": "2021-12-01",
      "completion_date": "2023-01-20",
      "has_results": false,
      "last_update_posted_date": "2023-02-01",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05223842"
    },
    {
      "nct_id": "NCT04827901",
      "title": "XEN1101 for Major Depressive Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "XEN1101",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James Murrough",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 44,
      "start_date": "2021-10-19",
      "completion_date": "2024-11-07",
      "has_results": false,
      "last_update_posted_date": "2025-04-02",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 2,
      "location_summary": "New York, New York • Houston, Texas",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04827901"
    },
    {
      "nct_id": "NCT05617898",
      "title": "Determining the Role of Social Reward Learning in Social Anhedonia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Psychosis"
      ],
      "interventions": [
        {
          "name": "Motivational Interviewing",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition Didactic Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 152,
      "start_date": "2023-06-14",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2025-07-24",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 2,
      "location_summary": "Birmingham, Alabama • Los Angeles, California",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05617898"
    },
    {
      "nct_id": "NCT07386730",
      "title": "A Study of Psychedelics in Healthy Older Adults With Low Well-being",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anhedonia in Healthy Volunteers",
        "Older Adults (50-90 Years)"
      ],
      "interventions": [
        {
          "name": "Psilocybin (drug)",
          "type": "DRUG"
        },
        {
          "name": "Dextromethorphan (DXM)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jennifer Mitchell",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "50 Years to 85 Years"
      },
      "enrollment_count": 80,
      "start_date": "2026-06-01",
      "completion_date": "2030-02",
      "has_results": false,
      "last_update_posted_date": "2026-06-08",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07386730"
    },
    {
      "nct_id": "NCT07607938",
      "title": "Psilocybin as a Novel Therapy for Residual Anhedonia",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Anhedonia",
        "Emotional Blunting"
      ],
      "interventions": [
        {
          "name": "Psilocybin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 90,
      "start_date": "2026-07",
      "completion_date": "2030-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-27",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07607938"
    },
    {
      "nct_id": "NCT07467473",
      "title": "Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in Depression",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Left Rostromedial Prefrontal Cortex - Accelerated Intermittent Theta Burst",
        "Left Dorsolateral Prefrontal Cortex - Accelerated Intermittent Theta Burst",
        "Left Primary Somatosensory Cortex - Accelerated Intermittent Theta Burst"
      ],
      "interventions": [
        {
          "name": "Accelerated Intermittent Theta Burst Transcranial Magnetic Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Florida State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 48,
      "start_date": "2026-03-23",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-20",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "Tallahassee, Florida",
      "locations": [
        {
          "city": "Tallahassee",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07467473"
    },
    {
      "nct_id": "NCT07493317",
      "title": "Neutralizing Interleukin (IL)-6",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Major Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "Tocilizumab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 60,
      "start_date": "2026-03-26",
      "completion_date": "2031-02-06",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07493317"
    },
    {
      "nct_id": "NCT05487885",
      "title": "Anhedonia, Development, and Emotions: Phenotyping and Therapeutics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Depression",
        "Anhedonia"
      ],
      "interventions": [
        {
          "name": "Continuous theta burst stimulation (cTBS)",
          "type": "DEVICE"
        },
        {
          "name": "Positive Affect Training",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Ketamine Injectable Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "Erika Forbes",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "15 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "15 Years to 25 Years"
      },
      "enrollment_count": 123,
      "start_date": "2022-07-22",
      "completion_date": "2025-06-01",
      "has_results": true,
      "last_update_posted_date": "2026-03-17",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05487885"
    },
    {
      "nct_id": "NCT05629520",
      "title": "A Neurobiological Model of Anhedonia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Anhedonia",
        "Depression"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Milton S. Hershey Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2020-02-19",
      "completion_date": "2024-07-30",
      "has_results": false,
      "last_update_posted_date": "2024-10-16",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "Hershey, Pennsylvania",
      "locations": [
        {
          "city": "Hershey",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05629520"
    },
    {
      "nct_id": "NCT02498925",
      "title": "Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anhedonia"
      ],
      "interventions": [
        {
          "name": "Behavioral Activation",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mclean Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "13 Years to 18 Years"
      },
      "enrollment_count": 80,
      "start_date": "2015-12",
      "completion_date": "2023-05",
      "has_results": true,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-06-11T01:20:44.559Z",
      "location_count": 1,
      "location_summary": "Belmont, Massachusetts",
      "locations": [
        {
          "city": "Belmont",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02498925"
    }
  ]
}