{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diphtheria",
    "query": {
      "condition": "Diphtheria"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 82,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diphtheria&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T05:38:10.874Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00133445",
      "title": "Pentavalent DTaP-Hep B-IPV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diphtheria",
        "Hepatitis B",
        "Poliomyelitis",
        "Pertussis",
        "Tetanus"
      ],
      "interventions": [
        {
          "name": "DTaP-Hep B-IPV Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Monovalent Hep B Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "5 Days",
        "sex": "ALL",
        "summary": "Up to 5 Days"
      },
      "enrollment_count": 5,
      "start_date": "2005-12",
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2011-11-07",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 1,
      "location_summary": "Torrance, California",
      "locations": [
        {
          "city": "Torrance",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00133445"
    },
    {
      "nct_id": "NCT00835237",
      "title": "Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tetanus",
        "Acellular Pertussis",
        "Diphtheria",
        "Diphtheria-Tetanus-acellular Pertussis Vaccines"
      ],
      "interventions": [
        {
          "name": "Boostrix®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Decavac™",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1332,
      "start_date": "2009-02-17",
      "completion_date": "2009-10-15",
      "has_results": true,
      "last_update_posted_date": "2020-01-03",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 24,
      "location_summary": "Tucson, Arizona • Los Angeles, California • DeLand, Florida + 21 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Stockbridge",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00835237"
    },
    {
      "nct_id": "NCT06588530",
      "title": "PFAS Exposure and Immune Response to Vaccination in Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Innate Inflammatory Response",
        "Vaccination",
        "Diphtheria",
        "Tetanus",
        "Environmental Exposure",
        "Vaccine",
        "Antibodies",
        "Adult",
        "Immunity",
        "Pollution; Exposure"
      ],
      "interventions": [
        {
          "name": "TENIVAC",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Rutgers, The State University of New Jersey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-11-04",
      "completion_date": "2025-01-08",
      "has_results": true,
      "last_update_posted_date": "2025-12-30",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 1,
      "location_summary": "Paulsboro, New Jersey",
      "locations": [
        {
          "city": "Paulsboro",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06588530"
    },
    {
      "nct_id": "NCT00255047",
      "title": "Safety and Immune Response of Different Pediatric Combination Vaccines.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Diphtheria",
        "Polio",
        "Pertussis"
      ],
      "interventions": [
        {
          "name": "DAPTACEL®. (DTaP), IPOL®., and ActHIB®.",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pentacel®: DTaP-IPV/Hib combined",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP-IPV and ActHIB®",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "89 Days",
        "sex": "ALL",
        "summary": "42 Days to 89 Days"
      },
      "enrollment_count": 2167,
      "start_date": "2005-11",
      "completion_date": "2009-02",
      "has_results": true,
      "last_update_posted_date": "2014-02-14",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 36,
      "location_summary": "Tuscaloosa, Alabama • Fayetteville, Arkansas • Jonesboro, Arkansas + 29 more",
      "locations": [
        {
          "city": "Tuscaloosa",
          "state": "Alabama"
        },
        {
          "city": "Fayetteville",
          "state": "Arkansas"
        },
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00255047"
    },
    {
      "nct_id": "NCT03463577",
      "title": "The Safety of Boostrix Following Routine Immunization of Pregnant Women",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Whooping Cough"
      ],
      "interventions": [
        {
          "name": "Safety assessment following routine immunization with Boostrix",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "Female only"
      },
      "enrollment_count": 65783,
      "start_date": "2018-04-13",
      "completion_date": "2020-08-04",
      "has_results": true,
      "last_update_posted_date": "2022-05-18",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 1,
      "location_summary": "Pasadena, California",
      "locations": [
        {
          "city": "Pasadena",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03463577"
    },
    {
      "nct_id": "NCT00777790",
      "title": "Study of a Booster Dose of Meningococcal Diphtheria Toxoid Conjugate Vaccine in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Meningitis",
        "Meningococcemia"
      ],
      "interventions": [
        {
          "name": "Meningococcal Polysaccharide Diphtheria Toxoid Conjugate",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "13 Years to 21 Years"
      },
      "enrollment_count": 241,
      "start_date": "2004-02",
      "completion_date": "2005-04",
      "has_results": true,
      "last_update_posted_date": "2014-02-14",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 9,
      "location_summary": "Atlanta, Georgia • Marietta, Georgia • Woburn, Massachusetts + 6 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Woburn",
          "state": "Massachusetts"
        },
        {
          "city": "Albany",
          "state": "New York"
        },
        {
          "city": "Akron",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00777790"
    },
    {
      "nct_id": "NCT01897402",
      "title": "Immunogenicity and Safety of Group A, C, Y & W-135 Meningococcal Polysaccharide Diphtheria Toxoid Conjugate Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Meningococcal Meningitis",
        "Meningococcal Infections"
      ],
      "interventions": [
        {
          "name": "Test Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "US Licensed Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "JN-International Medical Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 525,
      "start_date": "2013-07",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2015-04-23",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 3,
      "location_summary": "Greenbelt, Maryland • Pasadena, Maryland • Towson, Maryland",
      "locations": [
        {
          "city": "Greenbelt",
          "state": "Maryland"
        },
        {
          "city": "Pasadena",
          "state": "Maryland"
        },
        {
          "city": "Towson",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01897402"
    },
    {
      "nct_id": "NCT02783170",
      "title": "Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Tetanus, Diphtheria, and Pertussis Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "2016-2017 Quadrivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "2017-2018 Quadrivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 81,
      "start_date": "2016-09",
      "completion_date": "2018-05-10",
      "has_results": true,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Durham, North Carolina • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02783170"
    },
    {
      "nct_id": "NCT04424693",
      "title": "Comparing the Incidence of Preeclampsia Between Pregnant Women Receiving Tdap Vaccinations at Week 28 or at Week 36",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pre-Eclampsia",
        "Diphtheria, Tetanus and Pertussis Vaccine Reaction"
      ],
      "interventions": [
        {
          "name": "Tdap Vaccine Administration",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Institute of Arthritis Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "42 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 42 Years · Female only"
      },
      "enrollment_count": 1600,
      "start_date": "2020-12-01",
      "completion_date": "2024-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-06-16",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 1,
      "location_summary": "Idaho Falls, Idaho",
      "locations": [
        {
          "city": "Idaho Falls",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04424693"
    },
    {
      "nct_id": "NCT00148941",
      "title": "Immune Response and Safety Comparison of 3 Lots of GSK Biologicals' DTaP-IPV Candidate Vaccine to DTaP + IPV Vaccines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tetanus",
        "Acellular Pertussis",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "SB213503 lot 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "SB213503 lot 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "SB213503 lot 3",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Infanrix",
          "type": "BIOLOGICAL"
        },
        {
          "name": "IPOL",
          "type": "BIOLOGICAL"
        },
        {
          "name": "M-M-R II",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "4 Years to 6 Years"
      },
      "enrollment_count": 4209,
      "start_date": "2005-01-06",
      "completion_date": "2006-12-04",
      "has_results": true,
      "last_update_posted_date": "2020-02-05",
      "last_synced_at": "2026-05-22T05:38:10.874Z",
      "location_count": 24,
      "location_summary": "Little Rock, Arkansas • Antioch, California • Daly City, California + 20 more",
      "locations": [
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Antioch",
          "state": "California"
        },
        {
          "city": "Daly City",
          "state": "California"
        },
        {
          "city": "Fairfield",
          "state": "California"
        },
        {
          "city": "Fremont",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00148941"
    }
  ]
}