{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diphtheria&page=4",
    "query": {
      "condition": "Diphtheria",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 82,
    "total_pages": 9,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diphtheria&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diphtheria&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-14T12:20:01.697Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00489970",
      "title": "Persistence Study of GSK Biologicals' Tdap Vaccine 1, 3, 5 and 9 Years Following Administration as an Initial Single Dose in Healthy Young Adults and to Evaluate the Immunogenicity and Safety of Boostrix as a Second Dose of Tdap, When Administered at Year 9",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Acellular Pertussis",
        "Tetanus",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "Taking of blood samples",
          "type": "PROCEDURE"
        },
        {
          "name": "Boostrix",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Adacel",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "28 Years",
        "maximum_age": "73 Years",
        "sex": "ALL",
        "summary": "28 Years to 73 Years"
      },
      "enrollment_count": 1954,
      "start_date": "2007-06-01",
      "completion_date": "2016-03-01",
      "has_results": true,
      "last_update_posted_date": "2020-05-01",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 37,
      "location_summary": "Huntsville, Alabama • Chandler, Arizona • Mesa, Arizona + 31 more",
      "locations": [
        {
          "city": "Huntsville",
          "state": "Alabama"
        },
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Mesa",
          "state": "Arizona"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00489970"
    },
    {
      "nct_id": "NCT00282295",
      "title": "US-licensed Combined Vaccine Against Tetanus & Diphtheria, Given With US-licensed Vaccine Against Meningococcal Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Acellular Pertussis",
        "Tetanus",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "Boostrix®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Menactra™",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "11 Years to 18 Years"
      },
      "enrollment_count": 1344,
      "start_date": "2006-01-25",
      "completion_date": "2006-08-08",
      "has_results": true,
      "last_update_posted_date": "2018-08-17",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 24,
      "location_summary": "Chandler, Arizona • Little Rock, Arkansas • Fountain Valley, California + 18 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Fountain Valley",
          "state": "California"
        },
        {
          "city": "Golden",
          "state": "Colorado"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00282295"
    },
    {
      "nct_id": "NCT00777257",
      "title": "Study of Menactra® in US Adolescents When Administered Concomitantly With Tdap Vaccine",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Meningitis",
        "Meningococcemia",
        "Pertussis",
        "Tetanus",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "T dap + Meningococcal Polysaccharide Diphtheria Toxoid Conj.",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tdap + Meningococcal Polysaccharide Diphtheria Toxoid Conj.",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Meningococcal Polysaccharide Diphtheria Toxoid Conj. + T dap",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "11 Years to 17 Years"
      },
      "enrollment_count": 1345,
      "start_date": "2005-04",
      "completion_date": "2007-09",
      "has_results": true,
      "last_update_posted_date": "2014-02-14",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 20,
      "location_summary": "Jonesboro, Arkansas • Little Rock, Arkansas • Boulder, Colorado + 17 more",
      "locations": [
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Boulder",
          "state": "Colorado"
        },
        {
          "city": "Marietta",
          "state": "Georgia"
        },
        {
          "city": "Woodstock",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00777257"
    },
    {
      "nct_id": "NCT04398706",
      "title": "Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Pneumococcal Immunisation",
        "Diphtheria Immunisation",
        "Tetanus Immunisation",
        "Pertussis Immunisation",
        "Hepatitis B Immunisation",
        "Haemophilus Influenzae Type b Immunisation",
        "Polio Immunisation",
        "Measles Immunisation",
        "Rubella Immunisation",
        "Varicella Immunisation",
        "Mumps Immunisation"
      ],
      "interventions": [
        {
          "name": "Pneumococcal Conjugate Vaccine formulation 1",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal Conjugate Vaccine formulation 2",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal Conjugate Vaccine formulation 3",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Varicella Virus Vaccine Live",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Measles, Mumps, and Rubella Virus Vaccine Live",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Diphtheria and Tetanus Toxoids and Acellular Pertussis Adsorbed, Inactivated Poliovirus and Haemophilus b Conjugate (Tetanus Toxoid Conjugate)",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Rotavirus Vaccine, Live, Oral, Pentavalent",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hepatitis B Vaccine* [Recombinant] *as applicable",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Sanofi Pasteur, a Sanofi Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "42 Days",
        "maximum_age": "15 Months",
        "sex": "ALL",
        "summary": "42 Days to 15 Months"
      },
      "enrollment_count": 852,
      "start_date": "2020-05-22",
      "completion_date": "2023-08-10",
      "has_results": true,
      "last_update_posted_date": "2025-09-08",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 49,
      "location_summary": "Jonesboro, Arkansas • Bellflower, California • Huntington Park, California + 41 more",
      "locations": [
        {
          "city": "Jonesboro",
          "state": "Arkansas"
        },
        {
          "city": "Bellflower",
          "state": "California"
        },
        {
          "city": "Huntington Park",
          "state": "California"
        },
        {
          "city": "Huntington Park",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04398706"
    },
    {
      "nct_id": "NCT04766086",
      "title": "Trial to Evaluate the Safety, Tolerability, and Immunogenicity of A Multivalent Group B Streptococcus Vaccine When Administered Concomitantly With Tdap in Healthy Nonpregnant Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Group B Streptococcus Infections"
      ],
      "interventions": [
        {
          "name": "Multivalent Group B streptococcus vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Tetanus, diphtheria, and acellular pertussis vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Placebo",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 49 Years · Female only"
      },
      "enrollment_count": 306,
      "start_date": "2022-08-12",
      "completion_date": "2023-04-27",
      "has_results": true,
      "last_update_posted_date": "2024-05-24",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 12,
      "location_summary": "Newton, Kansas • Omaha, Nebraska • Las Vegas, Nevada + 8 more",
      "locations": [
        {
          "city": "Newton",
          "state": "Kansas"
        },
        {
          "city": "Omaha",
          "state": "Nebraska"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        },
        {
          "city": "Wilmington",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04766086"
    },
    {
      "nct_id": "NCT03530124",
      "title": "Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Apnea",
        "Apnea Neonatal",
        "Prematurity"
      ],
      "interventions": [
        {
          "name": "PCV13",
          "type": "BIOLOGICAL"
        },
        {
          "name": "DTaP",
          "type": "BIOLOGICAL"
        },
        {
          "name": "HBV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "IPV",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Hib",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "6 Weeks and older"
      },
      "enrollment_count": 223,
      "start_date": "2018-07-17",
      "completion_date": "2021-11-01",
      "has_results": true,
      "last_update_posted_date": "2024-02-14",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 4,
      "location_summary": "Atlanta, Georgia • Chapel Hill, North Carolina • Durham, North Carolina + 1 more",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03530124"
    },
    {
      "nct_id": "NCT00871117",
      "title": "Immunogenicity and Safety of Kinrix + (Measles Mumps Rubella) MMR Vaccine With and Without Varicella Vaccine in Healthy Children 4-6 Years",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tetanus",
        "Acellular Pertussis",
        "Diphtheria"
      ],
      "interventions": [
        {
          "name": "GSK Biologicals'Kinrix®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Merck and Company's MMRII",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Merck and Company's Varivax",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "4 Years",
        "maximum_age": "6 Years",
        "sex": "ALL",
        "summary": "4 Years to 6 Years"
      },
      "enrollment_count": 478,
      "start_date": "2009-03-31",
      "completion_date": "2010-06-15",
      "has_results": true,
      "last_update_posted_date": "2018-08-22",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 11,
      "location_summary": "Antioch, California • Daly City, California • Hayward, California + 7 more",
      "locations": [
        {
          "city": "Antioch",
          "state": "California"
        },
        {
          "city": "Daly City",
          "state": "California"
        },
        {
          "city": "Hayward",
          "state": "California"
        },
        {
          "city": "Redwood City",
          "state": "California"
        },
        {
          "city": "Roseville",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00871117"
    },
    {
      "nct_id": "NCT00835237",
      "title": "Evaluation of GlaxoSmithKline Biologicals' Boostrix® Vaccine in Comparison With Decavac™ Vaccine.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Tetanus",
        "Acellular Pertussis",
        "Diphtheria",
        "Diphtheria-Tetanus-acellular Pertussis Vaccines"
      ],
      "interventions": [
        {
          "name": "Boostrix®",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Decavac™",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 1332,
      "start_date": "2009-02-17",
      "completion_date": "2009-10-15",
      "has_results": true,
      "last_update_posted_date": "2020-01-03",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 24,
      "location_summary": "Tucson, Arizona • Los Angeles, California • DeLand, Florida + 21 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "DeLand",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Stockbridge",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00835237"
    },
    {
      "nct_id": "NCT05169905",
      "title": "A Study to Evaluate the Safety and Immune Response to an Unadjuvanted RSV Maternal Vaccine in Healthy Non-pregnant Females From 9 to 49 Years of Age",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Respiratory Syncytial Virus Infections"
      ],
      "interventions": [
        {
          "name": "RSV MAT vaccine",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "dTpa vaccine",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "49 Years",
        "sex": "FEMALE",
        "summary": "9 Years to 49 Years · Female only"
      },
      "enrollment_count": 9,
      "start_date": "2022-02-02",
      "completion_date": "2022-08-03",
      "has_results": true,
      "last_update_posted_date": "2023-04-07",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 2,
      "location_summary": "Miami, Florida • Beaumont, Texas",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Beaumont",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05169905"
    },
    {
      "nct_id": "NCT02783170",
      "title": "Safety and Immunogenicity of Simultaneous Tdap and IIV in Pregnant Women",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pregnancy"
      ],
      "interventions": [
        {
          "name": "Tetanus, Diphtheria, and Pertussis Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "2016-2017 Quadrivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "2017-2018 Quadrivalent Inactivated Influenza Vaccine",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 81,
      "start_date": "2016-09",
      "completion_date": "2018-05-10",
      "has_results": true,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-11-14T12:20:01.697Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Durham, North Carolina • Cincinnati, Ohio",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02783170"
    }
  ]
}