{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disabilities+Multiple&page=16",
    "query": {
      "condition": "Disabilities Multiple",
      "page": 16
    },
    "page_size": 10
  },
  "pagination": {
    "page": 16,
    "page_size": 10,
    "total_count": 363,
    "total_pages": 37,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disabilities+Multiple&page=17&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disabilities+Multiple&page=15&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-22T12:40:56.260Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02381457",
      "title": "SNP-based Microdeletion and Aneuploidy RegisTry (SMART)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "22q11 Deletion Syndrome",
        "DiGeorge Syndrome",
        "Trisomy 21",
        "Trisomy 18",
        "Trisomy 13",
        "Monosomy X",
        "Sex Chromosome Abnormalities",
        "Cri-du-Chat Syndrome",
        "Angelman Syndrome",
        "Prader-Willi Syndrome",
        "1p36 Deletion Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Natera, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "48 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 48 Years · Female only"
      },
      "enrollment_count": 20960,
      "start_date": "2015-04",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2021-01-29",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 16,
      "location_summary": "San Francisco, California • Camden, New Jersey • Mount Laurel, New Jersey + 10 more",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Camden",
          "state": "New Jersey"
        },
        {
          "city": "Mount Laurel",
          "state": "New Jersey"
        },
        {
          "city": "New Brunswick",
          "state": "New Jersey"
        },
        {
          "city": "Garden City",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02381457"
    },
    {
      "nct_id": "NCT07636811",
      "title": "A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Down Syndrome-Associated Alzheimer's Disease (DS-AD)"
      ],
      "interventions": [
        {
          "name": "Mivelsiran",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Alnylam Pharmaceuticals",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "40 Years to 55 Years"
      },
      "enrollment_count": 58,
      "start_date": "2026-08-17",
      "completion_date": "2031-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-13",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 4,
      "location_summary": "Maitland, Florida • Naples, Florida • Indianapolis, Indiana + 1 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Naples",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07636811"
    },
    {
      "nct_id": "NCT01390558",
      "title": "Gait Parameters of Persons With Down Syndrome With and Without Orthotics Using GaitRite",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Down Syndrome"
      ],
      "interventions": [
        {
          "name": "custom orthotics",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "2 Years to 80 Years"
      },
      "enrollment_count": 23,
      "start_date": "2011-06",
      "completion_date": "2018-08-27",
      "has_results": false,
      "last_update_posted_date": "2019-02-15",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01390558"
    },
    {
      "nct_id": "NCT00770458",
      "title": "Non-Invasive Screening for Fetal Aneuploidy: A New Maternal Plasma Marker",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Down Syndrome (Trisomy 21)",
        "Edwards Syndrome (Trisomy 18)",
        "Patau Syndrome (Trisomy 13)",
        "Turner Syndrome"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Sequenom, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1000,
      "start_date": "2008-06",
      "completion_date": "2009-12",
      "has_results": false,
      "last_update_posted_date": "2010-01-06",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 7,
      "location_summary": "La Jolla, California • San Diego, California • San Jose, California + 4 more",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Jose",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00770458"
    },
    {
      "nct_id": "NCT04416243",
      "title": "Feasibility of a High-intensity Interval Training Program in Persons With Multiple Sclerosis Who Have Walking Disability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Recumbent Stepping, High-Intensity Interval Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Texas, Denton, TX",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2019-12-19",
      "completion_date": "2022-12-14",
      "has_results": false,
      "last_update_posted_date": "2023-04-19",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "Denton, Texas",
      "locations": [
        {
          "city": "Denton",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04416243"
    },
    {
      "nct_id": "NCT05945784",
      "title": "Exploring Accessible Beauty for Individuals With Upper Extremity Deficits",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Ischemic",
        "Stroke Hemorrhagic",
        "Stroke (CVA) or TIA",
        "Stroke, Acute",
        "Traumatic Brain Injury",
        "SCI - Spinal Cord Injury",
        "Ehlers-Danlos Syndromes (EDS)",
        "Lupus Erythematosus",
        "Guillain-Barre Syndrome",
        "Multiple Sclerosis",
        "Myasthenia Gravis",
        "Amyotrophic Lateral Sclerosis",
        "Graves Disease",
        "Muscular Dystrophies"
      ],
      "interventions": [
        {
          "name": "Use of Rare Beauty makeup products",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Casa Colina Hospital and Centers for Healthcare",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 57,
      "start_date": "2023-07-21",
      "completion_date": "2023-09-29",
      "has_results": false,
      "last_update_posted_date": "2023-12-06",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "Pomona, California",
      "locations": [
        {
          "city": "Pomona",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05945784"
    },
    {
      "nct_id": "NCT06537648",
      "title": "Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Down Syndrome",
        "Physical Inactivity"
      ],
      "interventions": [
        {
          "name": "Decreasing Alzheimer's Risk Through oNline Choreographed Exercise - Down Syndrome Program",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Kansas Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "18 Years to 64 Years"
      },
      "enrollment_count": 20,
      "start_date": "2024-08-02",
      "completion_date": "2025-05-09",
      "has_results": true,
      "last_update_posted_date": "2026-03-13",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "Kansas City, Kansas",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06537648"
    },
    {
      "nct_id": "NCT03804047",
      "title": "KITAMS: Kinesio Tape and Physical Function in Persons With Multiples Sclerosis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "kinesio tape",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northern Illinois University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-01-01",
      "completion_date": "2021-12-31",
      "has_results": false,
      "last_update_posted_date": "2021-03-03",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "DeKalb, Illinois",
      "locations": [
        {
          "city": "DeKalb",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03804047"
    },
    {
      "nct_id": "NCT03653390",
      "title": "A Community Wellness Program for Adults Living With Long-term Physical Disability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Disability"
      ],
      "interventions": [
        {
          "name": "EnhanceWellness for Disability (EW-D)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wellness Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Washington",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "64 Years",
        "sex": "ALL",
        "summary": "45 Years to 64 Years"
      },
      "enrollment_count": 516,
      "start_date": "2019-01-31",
      "completion_date": "2022-11-14",
      "has_results": true,
      "last_update_posted_date": "2023-11-21",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03653390"
    },
    {
      "nct_id": "NCT01238250",
      "title": "Online Study of People Who Have Genetic Changes and Features of Autism: Simons Searchlight",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "16P11.2 Deletion Syndrome",
        "16p11.2 Duplications",
        "1Q21.1 Deletion",
        "1Q21.1 Microduplication Syndrome (Disorder)",
        "ACTL6B",
        "ADNP",
        "AHDC1",
        "ANK2",
        "ANKRD11",
        "ARID1B",
        "ASH1L",
        "BCL11A",
        "CHAMP1",
        "CHD2",
        "CHD8",
        "CSNK2A1",
        "CTBP1",
        "CTNNB1 Gene Mutation",
        "CUL3",
        "DDX3X",
        "DNMT3A",
        "DSCAM",
        "DYRK1A",
        "FOXP1",
        "GRIN2A",
        "GRIN2B",
        "HIVEP2-Related Intellectual Disability",
        "HNRNPH2",
        "KATNAL2",
        "KDM5B",
        "KDM6B",
        "KMT2C Gene Mutation",
        "KMT2E",
        "KMT5B",
        "MBD5",
        "MED13L",
        "PACS1",
        "PPP2R5D-Related Intellectual Disability",
        "PTCHD1",
        "REST",
        "SCN2A Encephalopathy",
        "SETBP1 Gene Mutation",
        "SETD5",
        "SMARCA4 Gene Mutation",
        "SMARCC2",
        "STXBP1 Encephalopathy With Epilepsy",
        "SYNGAP1-Related Intellectual Disability",
        "TBR1",
        "ARHGEF9",
        "HNRNPU",
        "PPP3CA",
        "PPP2R1A",
        "SLC6A1",
        "2p16.3 Deletions",
        "5q35 Deletions",
        "5q35 Duplications",
        "7q11.23 Duplications",
        "15Q13.3 Deletion Syndrome",
        "16p11.2 Triplications",
        "16P12.2 Microdeletion",
        "16P13.11 Microdeletion Syndrome (Disorder)",
        "17Q12 Microdeletion Syndrome (Disorder)",
        "17Q12 Duplication Syndrome",
        "17Q21.31 Deletion Syndrome",
        "17q21.3 Duplications",
        "ACTB",
        "ADSL",
        "AFF2",
        "ALDH5A1",
        "ANK3",
        "ARX",
        "ATRX Gene Mutation",
        "AUTS2 Syndrome",
        "BCKDK",
        "BRSK2",
        "CACNA1C",
        "CAPRIN1",
        "CASK",
        "CASZ1",
        "CHD3",
        "CIC",
        "CNOT3",
        "CREBBP Gene Mutation",
        "CSDE1",
        "CTCF",
        "DEAF1",
        "DHCR7",
        "DLG4",
        "EBF3",
        "EHMT1",
        "EP300 Gene Mutation",
        "GIGYF1",
        "GRIN1",
        "GRIN2D",
        "IQSEC2-Related Syndromic Intellectual Disability",
        "IRF2BPL",
        "KANSL1",
        "KCNB1",
        "KDM3B",
        "NEXMIF",
        "KMT2A",
        "MBOAT7",
        "MEIS2",
        "MYT1L",
        "NAA15",
        "NBEA",
        "NCKAP1",
        "NIPBL",
        "NLGN2",
        "NLGN3",
        "NLGN4X",
        "NR4A2",
        "NRXN1",
        "NRXN2",
        "NSD1 Gene Mutation",
        "PHF21A",
        "PHF3",
        "PHIP",
        "PSMD12",
        "RELN",
        "RERE",
        "RFX3",
        "RIMS1",
        "RORB",
        "SCN1A",
        "SETD2 Gene Mutation",
        "SHANK2",
        "SIN3A",
        "SLC9A6",
        "SON",
        "SOX5",
        "SPAST",
        "SRCAP",
        "TAOK1",
        "TANC2",
        "TCF20",
        "TLK2",
        "TRIO",
        "TRIP12",
        "UPF3B",
        "USP9X",
        "VPS13B",
        "WAC",
        "WDFY3",
        "ZBTB20",
        "ZNF292",
        "ZNF462",
        "2Q37 Deletion Syndrome",
        "9q34 Duplications",
        "15q15 Deletions",
        "15Q24 Deletion",
        "NR3C2",
        "SYNCRIP",
        "2q37.3 Deletion",
        "6q16 Deletion",
        "15q11.2 BP1-BP2 Deletion",
        "16p13.3 Deletion",
        "17Q11.2 Microduplication Syndrome (Disorder)",
        "17p13.3",
        "Xq28 Duplication",
        "CLCN4",
        "CSNK2B",
        "DYNC1H1",
        "EIF3F",
        "GNB1",
        "MED13",
        "MEF2C",
        "RALGAPB",
        "SCN1B",
        "YY1",
        "Xp11.22 Duplication",
        "PACS2",
        "MAOA",
        "MAOB",
        "HNRNPC",
        "HNRNPD",
        "HNRNPK",
        "HNRNPR",
        "HNRNPUL2",
        "5P Deletion Syndrome",
        "TCF7L2 Gene Mutation",
        "HECW2",
        "PPM1D",
        "RNU4-2",
        "SNAP25",
        "FOXP2",
        "ITSN1"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Simons Searchlight",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 100000,
      "start_date": "2010-10",
      "completion_date": "2050-10",
      "has_results": false,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-10-22T12:40:56.260Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Lewisburg, Pennsylvania",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Lewisburg",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01238250"
    }
  ]
}