{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Circulatory+System&page=54",
    "query": {
      "condition": "Diseases of the Circulatory System",
      "page": 54
    },
    "page_size": 10
  },
  "pagination": {
    "page": 54,
    "page_size": 10,
    "total_count": 3305,
    "total_pages": 331,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Circulatory+System&page=55&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Circulatory+System&page=53&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-17T21:03:43.032Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01729286",
      "title": "Health Economic Assessment of Lower Extremity Diabetic (HEALED) Ulcers With PriMatrix",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Foot Ulcer, Diabetic"
      ],
      "interventions": [
        {
          "name": "PriMatrix Moist Wound Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care Moist Wound Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Integra LifeSciences Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 92,
      "start_date": "2012-09",
      "completion_date": "2016-10",
      "has_results": false,
      "last_update_posted_date": "2016-10-18",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 15,
      "location_summary": "Los Angeles, California • Miami, Florida • Tampa, Florida + 11 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01729286"
    },
    {
      "nct_id": "NCT01241305",
      "title": "One-Time DNA Study for Vasculitis",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss)",
        "Giant Cell Arteritis",
        "Granulomatosis With Polyangiitis (Wegener's)",
        "Microscopic Polyangiitis",
        "Polyarteritis Nodosa",
        "Takayasu's Arteritis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 1000,
      "start_date": "2010-10",
      "completion_date": "2028-08",
      "has_results": false,
      "last_update_posted_date": "2026-01-22",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 11,
      "location_summary": "Los Angeles, California • San Francisco, California • Chicago, Illinois + 8 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Kansas City",
          "state": "Kansas"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01241305"
    },
    {
      "nct_id": "NCT00738894",
      "title": "GORE® Septal Occluder Device for Patent Foramen Ovale (PFO) Closure in Stroke Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Transient Ischemic Attack"
      ],
      "interventions": [
        {
          "name": "Septal Occluder Device",
          "type": "DEVICE"
        },
        {
          "name": "Antiplatelet Medical Therapy",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "W.L.Gore & Associates",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 664,
      "start_date": "2008-12-10",
      "completion_date": "2020-05-11",
      "has_results": true,
      "last_update_posted_date": "2020-11-20",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00738894"
    },
    {
      "nct_id": "NCT00743288",
      "title": "Melphalan and Panobinostat (LBH589) for the Treatment of Patients With Recurrent Multiple Myeloma",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Multiple Myeloma"
      ],
      "interventions": [
        {
          "name": "Melphalan",
          "type": "DRUG"
        },
        {
          "name": "Panobinostat",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Oncotherapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 40,
      "start_date": "2008-07",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2014-05-08",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 4,
      "location_summary": "Bakersfield, California • West Hollywood, California • Denver, Colorado + 1 more",
      "locations": [
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "West Hollywood",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00743288"
    },
    {
      "nct_id": "NCT00569842",
      "title": "Investigation of the Cylex® ImmuKnow® Assay",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Leukemia",
        "Non-Hodgkin's Lymphoma",
        "Chronic Lymphocytic Leukemia",
        "Hodgkin's Disease",
        "Multiple Myeloma",
        "Myelodysplastic Syndromes",
        "Myeloproliferative Disorders",
        "Aplastic Anemia",
        "Chronic Myelogenous Leukemia"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2007-11",
      "completion_date": "2012-12",
      "has_results": false,
      "last_update_posted_date": "2014-09-11",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00569842"
    },
    {
      "nct_id": "NCT03219749",
      "title": "Sleep Apnea, Cardiovascular and Exercise Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea",
        "Vascular Diseases",
        "Obesity"
      ],
      "interventions": [
        {
          "name": "exercise training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Towson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 60,
      "start_date": "2017-01-15",
      "completion_date": "2019-06-30",
      "has_results": false,
      "last_update_posted_date": "2019-09-10",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "Towson, Maryland",
      "locations": [
        {
          "city": "Towson",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03219749"
    },
    {
      "nct_id": "NCT07738978",
      "title": "Understanding and Enhancing Human Health and Movement",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury",
        "Stroke (CVA) or Transient Ischemic Attack",
        "Multiple Sclerosis"
      ],
      "interventions": [
        {
          "name": "Neural Prosthesis",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Louis Stokes VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2021-03-21",
      "completion_date": "2034-03-21",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07738978"
    },
    {
      "nct_id": "NCT02402426",
      "title": "Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Healthy",
        "Neurodegenerative Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200000,
      "start_date": "2013-09",
      "completion_date": "2030-09",
      "has_results": false,
      "last_update_posted_date": "2026-01-13",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02402426"
    },
    {
      "nct_id": "NCT05610085",
      "title": "A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Neonatal Seizure",
        "Neonatal Encephalopathy",
        "Hypoxic-Ischemic Encephalopathy",
        "Seizure Newborn"
      ],
      "interventions": [
        {
          "name": "Levetiracetam Injection",
          "type": "DRUG"
        },
        {
          "name": "Phenobarbital Sodium Injection",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Month",
        "sex": "ALL",
        "summary": "Up to 1 Month"
      },
      "enrollment_count": 133,
      "start_date": "2023-03-24",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-10-15",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 2,
      "location_summary": "San Diego, California • Minneapolis, Minnesota",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05610085"
    },
    {
      "nct_id": "NCT01894152",
      "title": "XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS) China Single-Arm Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Angioplasty",
        "Cardiovascular Disease",
        "Coronary Artery Disease",
        "Coronary Heart Disease",
        "Coronary Restenosis",
        "Myocardial Infarction",
        "Stent Thrombosis",
        "Vascular Disease"
      ],
      "interventions": [
        {
          "name": "XIENCE PRIME Everolimus Eluting Coronary Stent System (EECSS)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Abbott Medical Devices",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2002,
      "start_date": "2013-07",
      "completion_date": "2019-10-09",
      "has_results": true,
      "last_update_posted_date": "2020-05-26",
      "last_synced_at": "2026-10-17T21:03:43.032Z",
      "location_count": 1,
      "location_summary": "Santa Clara, California",
      "locations": [
        {
          "city": "Santa Clara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01894152"
    }
  ]
}