{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Musculoskeletal+System+and+Connective+Tissue&page=4", "query": { "condition": "Diseases of the Musculoskeletal System and Connective Tissue", "page": 4 }, "page_size": 10 }, "pagination": { "page": 4, "page_size": 10, "total_count": 989, "total_pages": 99, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Musculoskeletal+System+and+Connective+Tissue&page=5&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Diseases+of+the+Musculoskeletal+System+and+Connective+Tissue&page=3&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-24T01:04:47.393Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT06663332", "title": "A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Crohns Disease", "Colitis, Ulcerative", "Arthritis, Psoriatic", "Arthritis, Juvenile" ], "interventions": [ { "name": "Guselkumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Janssen Research & Development, LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "3 Years", "maximum_age": null, "sex": "ALL", "summary": "3 Years and older" }, "enrollment_count": 196, "start_date": "2024-10-29", "completion_date": "2032-02-25", "has_results": false, "last_update_posted_date": "2026-09-25", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 6, "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • Cincinnati, Ohio + 2 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06663332" }, { "nct_id": "NCT02051114", "title": "Discovering the Antecedents of Rheumatoid Arthritis Flare", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [], "intervention_types": [], "sponsor": "Rockefeller University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "65 Years", "sex": "FEMALE", "summary": "40 Years to 65 Years · Female only" }, "enrollment_count": 25, "start_date": "2014-02", "completion_date": "2030-02", "has_results": false, "last_update_posted_date": "2026-04-16", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02051114" }, { "nct_id": "NCT03840928", "title": "PatientSpot Formerly Known as ArthritisPower", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis", "Ankylosing Spondylitis", "Fibromyalgia", "Gout", "Crohn Disease", "Juvenile Idiopathic Arthritis", "Lupus Erythematosus", "Myositis", "Osteoarthritis", "Osteoporosis", "Psoriasis", "Psoriatic Arthritis", "Scleroderma", "Dermatomyositis", "Inflammatory Bowel Diseases", "Polymyositis", "Axial Spondyloarthritis", "Diffuse Idiopathic Skeletal Hyperostosis", "Polymyalgia Rheumatica", "Giant Cell Arteritis", "Temporal Arteritis", "Wegener", "Relapsing Polychondritis", "Undifferentiated Connective Tissue Disease", "Spinal Cord Injuries", "Alzheimer Disease", "Amyotrophic Lateral Sclerosis", "Ataxia", "Bell Palsy", "Brain Tumor", "Cerebral Aneurysm", "Epilepsy", "Guillain-Barre Syndrome", "Headache", "Head Injury", "Hydrocephalus", "Lumbar Disc Disease", "Meningitis", "Multiple Sclerosis", "Muscular Dystrophy", "Neurocutaneous Syndromes", "Parkinson Disease", "Stroke", "Cluster Headache", "Tension-Type Headache", "Chronic Obstructive Pulmonary Disease", "Asthma", "Lung Cancer", "Cystic Fibrosis", "Sleep Apnea", "Eczema", "Alopecia", "Chronic Inflammation", "Unstable Angina", "Heart Attack", "Heart Failure", "Arrythmia", "Valve Heart Disease", "High Blood Pressure", "Congenital Heart Disease", "Peripheral Arterial Disease", "Diabetes", "Chronic Liver Disease", "Obesity" ], "interventions": [], "intervention_types": [], "sponsor": "Global Healthy Living Foundation", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "19 Years", "maximum_age": null, "sex": "ALL", "summary": "19 Years and older" }, "enrollment_count": 40000, "start_date": "2015-04-01", "completion_date": "2025-03-01", "has_results": false, "last_update_posted_date": "2023-12-13", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 1, "location_summary": "Upper Nyack, New York", "locations": [ { "city": "Upper Nyack", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT03840928" }, { "nct_id": "NCT05814627", "title": "Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Upadacitinib", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Upadacitinib Matching Placebo", "type": "DRUG" }, { "name": "Adalimumab Matching Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 487, "start_date": "2023-06-15", "completion_date": "2026-07-15", "has_results": false, "last_update_posted_date": "2026-08-14", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 85, "location_summary": "Flagstaff, Arizona • Glendale, Arizona • Peoria, Arizona + 75 more", "locations": [ { "city": "Flagstaff", "state": "Arizona" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT05814627" }, { "nct_id": "NCT00048542", "title": "Study of Human Anti-TNF Monoclonal Antibody Adalimumab in Children With Polyarticular Juvenile Idiopathic Arthritis (JIA)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Arthritis, Juvenile Idiopathic" ], "interventions": [ { "name": "Double-Blind Adalimumab/Placebo + MTX", "type": "BIOLOGICAL" }, { "name": "Double-Blind Adalimumab/Placebo", "type": "BIOLOGICAL" }, { "name": "OLE BSA Adalimumab +/- MTX", "type": "DRUG" }, { "name": "OLE FD Adalimumab +/- MTX", "type": "DRUG" } ], "intervention_types": [ "BIOLOGICAL", "DRUG" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "17 Years", "sex": "ALL", "summary": "4 Years to 17 Years" }, "enrollment_count": 171, "start_date": "2002-09", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2011-08-22", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 15, "location_summary": "Birmingham, Alabama • Los Angeles, California • Stanford, California + 12 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Los Angeles", "state": "California" }, { "city": "Stanford", "state": "California" }, { "city": "Delray Beach", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00048542" }, { "nct_id": "NCT04402086", "title": "Rheumatology Patient Registry and Biorepository", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatic Diseases", "Adult Onset Still Disease", "Ankylosing Spondylitis", "Psoriatic Arthritis", "Reactive Arthritis", "Antiphospholipid Syndrome", "Systemic Lupus Erythematosus", "Behcet Disease", "Dermatomyositis", "Polymyositis", "Giant Cell Arteritis", "Lyme Disease", "Mixed Connective Tissue Disease", "Polymyalgia Rheumatica", "Rheumatoid Arthritis", "Sarcoidosis", "Systemic Sclerosis", "Scleroderma", "Sjogren's Syndrome", "Undifferentiated Connective Tissue Diseases" ], "interventions": [], "intervention_types": [], "sponsor": "Yale University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 5000, "start_date": "2020-08-04", "completion_date": "2030-06-01", "has_results": false, "last_update_posted_date": "2026-02-13", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 1, "location_summary": "New Haven, Connecticut", "locations": [ { "city": "New Haven", "state": "Connecticut" } ], "official_url": "https://clinicaltrials.gov/study/NCT04402086" }, { "nct_id": "NCT00162266", "title": "Abatacept With Methotrexate- Phase IIB", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Abatacept (BMS-188667)", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bristol-Myers Squibb", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 524, "start_date": "2000-10", "completion_date": "2009-09", "has_results": true, "last_update_posted_date": "2012-06-01", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 26, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Long Beach, California + 23 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Long Beach", "state": "California" }, { "city": "Highlands Ranch", "state": "Colorado" }, { "city": "Largo", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00162266" }, { "nct_id": "NCT00106522", "title": "A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Methotrexate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "tocilizumab [RoActemra/Actemra]", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 499, "start_date": "2005-05", "completion_date": "2007-11", "has_results": false, "last_update_posted_date": "2016-11-02", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 97, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Scottsdale, Arizona + 81 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00106522" }, { "nct_id": "NCT01814397", "title": "Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Breast Cancer", "Pain", "Arthralgia" ], "interventions": [ { "name": "Anastrozole", "type": "DRUG" }, { "name": "exemestane", "type": "DRUG" }, { "name": "letrozole", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Michigan Rogel Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": null, "sex": "FEMALE", "summary": "21 Years and older · Female only" }, "enrollment_count": 50, "start_date": "2009-07", "completion_date": "2013-02", "has_results": true, "last_update_posted_date": "2024-02-07", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 1, "location_summary": "Ann Arbor, Michigan", "locations": [ { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT01814397" }, { "nct_id": "NCT00993668", "title": "Assessing the Use of Certolizumab Pegol in Adult Subjects With Rheumatoid Arthritis on the Antibody Response When Receiving Influenza Virus and Pneumococcal Vaccines", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Placebo", "type": "OTHER" }, { "name": "Certolizumab pegol", "type": "BIOLOGICAL" } ], "intervention_types": [ "OTHER", "BIOLOGICAL" ], "sponsor": "UCB Pharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 224, "start_date": "2009-09", "completion_date": "2011-02", "has_results": true, "last_update_posted_date": "2018-08-01", "last_synced_at": "2026-10-24T01:04:47.393Z", "location_count": 41, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Tuscaloosa, Alabama + 38 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT00993668" } ] }