{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disorder+of+Fluid+Balance",
    "query": {
      "condition": "Disorder of Fluid Balance"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 15,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disorder+of+Fluid+Balance&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-07-22T22:02:09.422Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03262597",
      "title": "\"Beverage Hydration Index\" of Commercial Therapeutic Beverages",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "enterade",
          "type": "OTHER"
        },
        {
          "name": "Pedialyte",
          "type": "OTHER"
        },
        {
          "name": "Gatorade",
          "type": "OTHER"
        },
        {
          "name": "Water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sonoma State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 46,
      "start_date": "2017-02-17",
      "completion_date": "2017-04-14",
      "has_results": false,
      "last_update_posted_date": "2018-03-07",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Rohnert Park, California",
      "locations": [
        {
          "city": "Rohnert Park",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03262597"
    },
    {
      "nct_id": "NCT03857659",
      "title": "Serial Third Trimester Abdominal Circumference and Amniotic Fluid Measurements Versus Routine Care",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fetal Growth Abnormality",
        "Amniotic Fluid; Disorder"
      ],
      "interventions": [
        {
          "name": "Point-of-care ultrasound (POC-US)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Routine antenatal care",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Formal ultrasound",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 113,
      "start_date": "2019-04-05",
      "completion_date": "2020-05-20",
      "has_results": false,
      "last_update_posted_date": "2021-06-10",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03857659"
    },
    {
      "nct_id": "NCT00578695",
      "title": "THE BALANCE Study: Treatment of Hyponatremia Based on Lixivaptan in NYHA Class III/IV Cardiac Patient Evaluation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Hyponatremia"
      ],
      "interventions": [
        {
          "name": "lixivaptan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "CardioKine Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 652,
      "start_date": "2007-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2011-06-28",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 102,
      "location_summary": "Birmingham, Alabama • Mobile, Alabama • Bakersfield, California + 82 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Bakersfield",
          "state": "California"
        },
        {
          "city": "Banning",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00578695"
    },
    {
      "nct_id": "NCT03451253",
      "title": "Effects of an Amino Acid Mixture on Gastrointestinal Function, Inflammation and Fluid Balance: A Pilot Study in Patients With Inflammatory Bowel Disease",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inflammatory Bowel Diseases",
        "Short Bowel Syndrome",
        "Ileostomy - Stoma"
      ],
      "interventions": [
        {
          "name": "amino acid mixture beverage",
          "type": "OTHER"
        },
        {
          "name": "glucose-based sports drink",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Entrinsic Bioscience Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 7,
      "start_date": "2018-04-12",
      "completion_date": "2021-03-23",
      "has_results": false,
      "last_update_posted_date": "2023-03-23",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Nashua, New Hampshire • Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Nashua",
          "state": "New Hampshire"
        },
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03451253"
    },
    {
      "nct_id": "NCT01168583",
      "title": "Fluid Balance and Clinical Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fluid Balance",
        "Input and Output",
        "Inflammatory Mediators",
        "Acute Kidney Injury",
        "Mortality"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2010-07",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2011-09-21",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01168583"
    },
    {
      "nct_id": "NCT00085683",
      "title": "Herpes Virus-6 and Epilepsy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Epilepsy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 45,
      "start_date": "2004-06",
      "completion_date": "2005-07",
      "has_results": false,
      "last_update_posted_date": "2008-03-04",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00085683"
    },
    {
      "nct_id": "NCT03330704",
      "title": "Small-Volume, Patient-Specific, Balanced Hypertonic Fluid Protocol Validation",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cerebral Edema",
        "Saline Solution, Hypertonic"
      ],
      "interventions": [
        {
          "name": "3% Sodium Chloride",
          "type": "DRUG"
        },
        {
          "name": "23.4% Sodium Chloride",
          "type": "DRUG"
        },
        {
          "name": "8.4% Sodium Bicarbonate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2017-11-28",
      "completion_date": "2020-01-01",
      "has_results": false,
      "last_update_posted_date": "2020-03-19",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Stanford, California",
      "locations": [
        {
          "city": "Stanford",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03330704"
    },
    {
      "nct_id": "NCT01070199",
      "title": "Effects of Food Form and Fitness on Appetite and Digestion.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "High and Increasing Contribution of Energy From Beverages in the Diet May Enhance Positive Energy Balance and Weight Gain"
      ],
      "interventions": [
        {
          "name": "liquid to liquid",
          "type": "BEHAVIORAL"
        },
        {
          "name": "liquid to solid",
          "type": "BEHAVIORAL"
        },
        {
          "name": "solid to liquid",
          "type": "BEHAVIORAL"
        },
        {
          "name": "solid to solid",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Purdue University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 81,
      "start_date": "2009-01",
      "completion_date": "2010-12",
      "has_results": false,
      "last_update_posted_date": "2011-07-25",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01070199"
    },
    {
      "nct_id": "NCT01270854",
      "title": "Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wounds and Injuries",
        "Multiple Trauma",
        "Disorder of Fluid Balance"
      ],
      "interventions": [
        {
          "name": "Plasmalyte A",
          "type": "OTHER"
        },
        {
          "name": "Normal Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Davis",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2011-02",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Sacramento, California",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01270854"
    },
    {
      "nct_id": "NCT05092854",
      "title": "The Effect of AMP Human Sodium Bicarbonate Lotion on Dehydrated Heat Stress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fluid Retention",
        "Sodium Retention",
        "Heat Stress",
        "Dehydration (Physiology)",
        "Renal Injury",
        "Electrolyte and Fluid Balance Conditions"
      ],
      "interventions": [
        {
          "name": "PR Lotion - AMP Human Performance",
          "type": "OTHER"
        },
        {
          "name": "Placebo Lotion",
          "type": "OTHER"
        },
        {
          "name": "AminoVital - Rapid Recovery",
          "type": "OTHER"
        },
        {
          "name": "Placebo Supplement",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Connecticut",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "MALE",
        "summary": "18 Years to 45 Years · Male only"
      },
      "enrollment_count": 18,
      "start_date": "2021-09-03",
      "completion_date": "2022-08-01",
      "has_results": false,
      "last_update_posted_date": "2022-10-24",
      "last_synced_at": "2026-07-22T22:02:09.422Z",
      "location_count": 1,
      "location_summary": "Storrs, Connecticut",
      "locations": [
        {
          "city": "Storrs",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05092854"
    }
  ]
}