{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Disruptive+Mood+Dysregulation+Disorder",
    "query": {
      "condition": "Disruptive Mood Dysregulation Disorder"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-06-11T05:37:14.308Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00794040",
      "title": "A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mood Disorder",
        "Mental Disorder Diagnosed in Childhood",
        "Attention Deficit and Disruptive Behavior Disorder",
        "Attention Deficit Hyperactivity Disorder"
      ],
      "interventions": [
        {
          "name": "Add-on citalopram following optimized methylphenidate",
          "type": "DRUG"
        },
        {
          "name": "Add-on placebo following optimized methylphenidate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 103,
      "start_date": "2008-11-17",
      "completion_date": "2018-02-01",
      "has_results": true,
      "last_update_posted_date": "2019-05-07",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00794040"
    },
    {
      "nct_id": "NCT00025935",
      "title": "Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Mood Disorder"
      ],
      "interventions": [
        {
          "name": "Lithium",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "7 Years to 60 Years"
      },
      "enrollment_count": 2350,
      "start_date": "2002-01-01",
      "completion_date": null,
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00025935"
    },
    {
      "nct_id": "NCT05357495",
      "title": "Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disruptive Mood Dysregulation Disorder",
        "Attention Deficit Hyperactivity Disorder",
        "Normal Physiology"
      ],
      "interventions": [
        {
          "name": "Affective Posner fMRI frustration induction task",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "National Institute of Mental Health (NIMH)",
      "sponsor_class": "NIH",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2023-01-05",
      "completion_date": "2023-01-05",
      "has_results": false,
      "last_update_posted_date": "2023-01-10",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05357495"
    },
    {
      "nct_id": "NCT05930886",
      "title": "Focus Groups in Ethnically and Racially Diverse Families",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Attention Deficit/Hyperactivity Disorder",
        "Emotional Dysfunction",
        "Irritable Mood"
      ],
      "interventions": [
        {
          "name": "Focus Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 30,
      "start_date": "2023-04-15",
      "completion_date": "2025-10-04",
      "has_results": false,
      "last_update_posted_date": "2025-04-04",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05930886"
    },
    {
      "nct_id": "NCT06133231",
      "title": "Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Attention Deficit/Hyperactivity Disorder",
        "Emotional Dysfunction",
        "Irritable Mood"
      ],
      "interventions": [
        {
          "name": "Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "6 Years to 17 Years"
      },
      "enrollment_count": 30,
      "start_date": "2024-01-06",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-16",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06133231"
    },
    {
      "nct_id": "NCT03669289",
      "title": "Enhanced Support for Behavioral Barriers to Learning: An Evaluation of the SCHOOL STARS Program",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disruptive Behavior Disorder, Childhood Onset",
        "Attention Deficit Hyperactivity Disorder",
        "Oppositional Defiant Disorder in Children",
        "Disruptive Mood Dysregulation Disorder"
      ],
      "interventions": [
        {
          "name": "enhanced model of primary care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "5 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "5 Years to 12 Years"
      },
      "enrollment_count": 14,
      "start_date": "2018-09-14",
      "completion_date": "2019-04-30",
      "has_results": false,
      "last_update_posted_date": "2019-05-22",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03669289"
    },
    {
      "nct_id": "NCT01962623",
      "title": "Interpersonal Psychotherapy for Youth With Severe Mood Dysregulation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Severe Mood Dysregulation"
      ],
      "interventions": [
        {
          "name": "IPT-MBD",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 31,
      "start_date": "2013-08",
      "completion_date": "2015-10",
      "has_results": false,
      "last_update_posted_date": "2017-05-24",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01962623"
    },
    {
      "nct_id": "NCT01862549",
      "title": "Adapting DBT for Children With DMDD: Pilot RCT",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Disruptive Mood Dysregulation Disorder"
      ],
      "interventions": [
        {
          "name": "Dialectical Behavior Therapy for children",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "7 Years to 12 Years"
      },
      "enrollment_count": 43,
      "start_date": "2013-05",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2019-03-01",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "White Plains, New York",
      "locations": [
        {
          "city": "White Plains",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01862549"
    },
    {
      "nct_id": "NCT05712057",
      "title": "Neurostimulation Versus Therapy for Problems With Emotions",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Emotion Regulation",
        "Mood Disorders",
        "Stress Disorder",
        "Anxiety Disorders",
        "OCD",
        "Impulse Control Disorder",
        "Eating Disorders",
        "Emotional Dysfunction",
        "Emotional Instability",
        "Emotional Distress",
        "Emotional Maladjustment",
        "Emotional Impulsivity",
        "Obsessive-Compulsive Disorder",
        "Emotion Dysregulation",
        "Borderline Personality Disorder"
      ],
      "interventions": [
        {
          "name": "Repetitive Transcranial Magnetic Stimulation (rTMS)",
          "type": "DEVICE"
        },
        {
          "name": "electrical scalp stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Cognitive Restructuring",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Emotional Awareness Training",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 240,
      "start_date": "2023-05-15",
      "completion_date": "2027-12-01",
      "has_results": false,
      "last_update_posted_date": "2026-03-04",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05712057"
    },
    {
      "nct_id": "NCT02824627",
      "title": "Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Mood Disorder",
        "Disruptive Behavior Disorders"
      ],
      "interventions": [
        {
          "name": "Oxytocin",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "10 Years to 18 Years"
      },
      "enrollment_count": 58,
      "start_date": "2017-01-27",
      "completion_date": "2021-08-10",
      "has_results": true,
      "last_update_posted_date": "2023-10-05",
      "last_synced_at": "2026-06-11T05:37:14.308Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02824627"
    }
  ]
}