{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Distension&page=9",
    "query": {
      "condition": "Distension",
      "page": 9
    },
    "page_size": 10
  },
  "pagination": {
    "page": 9,
    "page_size": 10,
    "total_count": 288,
    "total_pages": 29,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Distension&page=10&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Distension&page=8&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-21T07:17:18.763Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03751631",
      "title": "Safety and Efficacy of Phenylephrine 2.5%-Tropicamide 1% Microdose Ophthalmic Solution for Pupil Dilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mydriasis"
      ],
      "interventions": [
        {
          "name": "Tropicamide 1%-Phenylephrine 2.5% ophthalmic solution (TR/PE)",
          "type": "DRUG"
        },
        {
          "name": "Tropicamide 1% ophthalmic solution (TR)",
          "type": "DRUG"
        },
        {
          "name": "Phenylephrine 2.5% ophthalmic solution (PE)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Eyenovia Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 70,
      "start_date": "2018-11-15",
      "completion_date": "2019-01-11",
      "has_results": true,
      "last_update_posted_date": "2022-03-18",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Cypress, California",
      "locations": [
        {
          "city": "Cypress",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03751631"
    },
    {
      "nct_id": "NCT06689904",
      "title": "The Effect of Eyedrop Size on Pupillary Dilation Using the Nanodropper Bottle Adapter",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Medication Delivery",
        "Eye Drop Delivery"
      ],
      "interventions": [
        {
          "name": "Nanodropper",
          "type": "DEVICE"
        },
        {
          "name": "Standard eye drop bottle",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Sutter Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 54,
      "start_date": "2022-01-04",
      "completion_date": "2022-01-31",
      "has_results": false,
      "last_update_posted_date": "2024-11-15",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06689904"
    },
    {
      "nct_id": "NCT01352546",
      "title": "Botox Injection for Treatment of Vaginismus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Vaginismus"
      ],
      "interventions": [
        {
          "name": "BOTOX",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Plastic Surgery Professional Association",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "40 Years",
        "sex": "FEMALE",
        "summary": "20 Years to 40 Years · Female only"
      },
      "enrollment_count": 31,
      "start_date": "2010-08",
      "completion_date": "2012-12",
      "has_results": true,
      "last_update_posted_date": "2017-08-07",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Manchester, New Hampshire",
      "locations": [
        {
          "city": "Manchester",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01352546"
    },
    {
      "nct_id": "NCT00043758",
      "title": "Multicenter, Randomized, Double-Blind, Placebo Controlled, Efficacy Study on the Effects of Tolvaptan on Left Ventricular Dilatation in Congestive Heart Failure Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Congestive Heart Failure"
      ],
      "interventions": [
        {
          "name": "Tolvaptan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Otsuka Pharmaceutical Development & Commercialization, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 170,
      "start_date": "2002-07",
      "completion_date": "2004-07",
      "has_results": false,
      "last_update_posted_date": "2005-06-24",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 35,
      "location_summary": "Tucson, Arizona • Little Rock, Arkansas • San Diego, California + 30 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Santa Rosa",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00043758"
    },
    {
      "nct_id": "NCT02116335",
      "title": "Endothelin Receptor Function and Acute Stress",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Bosentan",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Augusta University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 320,
      "start_date": "2015-06",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-01-28",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Augusta, Georgia",
      "locations": [
        {
          "city": "Augusta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02116335"
    },
    {
      "nct_id": "NCT04232670",
      "title": "Pancreatic Endotherapy for Refractory Chronic Pancreatitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pancreatic Duct Stone",
        "Pancreatic Duct Stricture",
        "Pancreatic Duct Dilatation"
      ],
      "interventions": [
        {
          "name": "EUS + SHAM",
          "type": "PROCEDURE"
        },
        {
          "name": "EUS + Pancreatic Endotherapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Oregon Health and Science University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14,
      "start_date": "2020-10-09",
      "completion_date": "2024-06-30",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 2,
      "location_summary": "Portland, Oregon • Charleston, South Carolina",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04232670"
    },
    {
      "nct_id": "NCT06369753",
      "title": "Visible Abdominal Distension",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Irritable Bowel Syndrome",
        "Dyspepsia",
        "Functional Bloating"
      ],
      "interventions": [
        {
          "name": "Biofeedback",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hospital Universitari Vall d'Hebron Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 100,
      "start_date": "2025-07-30",
      "completion_date": "2026-10",
      "has_results": false,
      "last_update_posted_date": "2025-10-31",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06369753"
    },
    {
      "nct_id": "NCT04177082",
      "title": "Safety and Effectiveness of the PXL-Platinum 330 System for CXL Using Riboflavin Solution",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Keratoconus",
        "Pellucid Marginal Corneal Degeneration",
        "Corneal Degeneration",
        "Corneal Ectasia"
      ],
      "interventions": [
        {
          "name": "PXL-330 Platinum device for crosslinking with Peschke riboflavin solution",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Cornea Associates of Texas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "8 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2020-01-10",
      "completion_date": "2022-05-05",
      "has_results": false,
      "last_update_posted_date": "2022-10-19",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04177082"
    },
    {
      "nct_id": "NCT00957840",
      "title": "Intraventricular Hemorrhage and Post Hemorrhagic Ventricular Dilation: Natural Course, Treatment, and Outcome",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intraventricular Hemorrhage",
        "Premature Infants"
      ],
      "interventions": [
        {
          "name": "NIRS, aEEG, and CSF concentration of biomarkers",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "1 Year",
        "sex": "ALL",
        "summary": "Up to 1 Year"
      },
      "enrollment_count": 63,
      "start_date": "2009-07",
      "completion_date": "2015-04",
      "has_results": false,
      "last_update_posted_date": "2015-05-06",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00957840"
    },
    {
      "nct_id": "NCT00315289",
      "title": "Study of Primary Surgical Treatment of Nasolacrimal Duct Obstruction in Children Less Than Four Years Old",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nasolacrimal Duct Obstruction"
      ],
      "interventions": [
        {
          "name": "Nasolacrimal balloon catheter duct dilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Nasolacrimal intubation",
          "type": "PROCEDURE"
        },
        {
          "name": "Simple Nasolacrimal duct probing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Jaeb Center for Health Research",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Months",
        "maximum_age": "47 Months",
        "sex": "ALL",
        "summary": "6 Months to 47 Months"
      },
      "enrollment_count": 973,
      "start_date": "2005-02",
      "completion_date": "2006-09",
      "has_results": false,
      "last_update_posted_date": "2010-03-02",
      "last_synced_at": "2026-10-21T07:17:18.763Z",
      "location_count": 2,
      "location_summary": "Baltimore, Maryland • Lancaster, Pennsylvania",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        },
        {
          "city": "Lancaster",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00315289"
    }
  ]
}