{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Distress%2C+Emotional",
    "query": {
      "condition": "Distress, Emotional"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 229,
    "total_pages": 23,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Distress%2C+Emotional&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-05-22T03:07:39.442Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05687162",
      "title": "SSIs for Mental Health and Loneliness",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Loneliness",
        "Mental Health Issue",
        "Distress, Emotional",
        "Depression",
        "Anxiety",
        "Stress"
      ],
      "interventions": [
        {
          "name": "Overcoming Loneliness three-week intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Overcoming Loneliness single-session intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Single-session \"Sharing Feelings\" program",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Blu Surfer program: a popular online content-based intervention for psychological distress",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Action Brings Change (ABC) Program (TEAM Lab version)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Online help-seeking as usual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "The Lonely Blu Surfer program: a popular online content-based intervention for loneliness",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Overcoming loneliness SSI 8-minute version",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, Irvine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 4370,
      "start_date": "2022-12-04",
      "completion_date": "2023-09-06",
      "has_results": false,
      "last_update_posted_date": "2024-07-22",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Irvine, California",
      "locations": [
        {
          "city": "Irvine",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05687162"
    },
    {
      "nct_id": "NCT03645759",
      "title": "Improving Quality of Life for Veterans With Stroke and Psychological Distress",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Stroke",
        "Depression",
        "Anxiety"
      ],
      "interventions": [
        {
          "name": "I'm Whole",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Education + usual care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 38,
      "start_date": "2019-11-20",
      "completion_date": "2021-12-21",
      "has_results": true,
      "last_update_posted_date": "2024-07-18",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03645759"
    },
    {
      "nct_id": "NCT05676255",
      "title": "The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Breast Cancer Female",
        "Psychological Distress"
      ],
      "interventions": [
        {
          "name": "Cognitively-Based Compassion Training for Survivors",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitively-Based Compassion Training for Dyads",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Health Education",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 452,
      "start_date": "2023-03-20",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2025-07-30",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05676255"
    },
    {
      "nct_id": "NCT07502352",
      "title": "Remotely-Delivered Cognitive Behavioral Stress Management for Breast Cancer (R-CBSM)",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Remotely Delivered Cognitive Behavioral Stress Management Intervention (R-CBSM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Standard of Care Survivorship Care Planning",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "50 Years and older · Female only"
      },
      "enrollment_count": 192,
      "start_date": "2026-05",
      "completion_date": "2029-08",
      "has_results": false,
      "last_update_posted_date": "2026-03-31",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Coral Gables, Florida",
      "locations": [
        {
          "city": "Coral Gables",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07502352"
    },
    {
      "nct_id": "NCT04035447",
      "title": "Symptom Management for YA Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer",
        "Young Adult",
        "Pain",
        "Psychological Distress",
        "Fatigue",
        "Breast Cancer",
        "Melanoma",
        "Hematologic Cancer",
        "Germ Cell Tumor",
        "Endocrine Cancer"
      ],
      "interventions": [
        {
          "name": "Behavioral Symptom Management for Young Adult Cancer Survivors",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 65,
      "start_date": "2020-01-22",
      "completion_date": "2024-06-15",
      "has_results": true,
      "last_update_posted_date": "2025-06-29",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04035447"
    },
    {
      "nct_id": "NCT01393821",
      "title": "Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dermatologic Complications",
        "Malignant Neoplasm",
        "Pain"
      ],
      "interventions": [
        {
          "name": "menadione topical lotion",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "OTHER"
        },
        {
          "name": "questionnaire administration",
          "type": "OTHER"
        },
        {
          "name": "management of therapy complications",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2012-01-23",
      "completion_date": "2018-07-14",
      "has_results": true,
      "last_update_posted_date": "2025-05-16",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona • Rochester, Minnesota",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01393821"
    },
    {
      "nct_id": "NCT05132881",
      "title": "Effect of (TaVNS) on Anxiety and Brain Function in Distressed Health Care Workers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anxiety",
        "Distress, Emotional",
        "Effects of Vibration",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Neuvana 2.0 Transcutaneous Auricular Vagal Nerve Stimulation (TaVNS)",
          "type": "OTHER"
        },
        {
          "name": "Waitlist Control",
          "type": "OTHER"
        },
        {
          "name": "Healthy Controls: Substudy Group III",
          "type": "OTHER"
        },
        {
          "name": "Distressed Workers: Subgroup II",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2021-04-01",
      "completion_date": "2025-11-20",
      "has_results": false,
      "last_update_posted_date": "2025-09-17",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05132881"
    },
    {
      "nct_id": "NCT01128777",
      "title": "Teens Coping With Parental Military Deployment",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Emotional Distress",
        "Behavior Problems"
      ],
      "interventions": [
        {
          "name": "Cognitive Behavioral Group Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nondirective supportive group therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brown University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 6,
      "start_date": "2011-01",
      "completion_date": "2012-04",
      "has_results": false,
      "last_update_posted_date": "2013-07-04",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Providence, Rhode Island",
      "locations": [
        {
          "city": "Providence",
          "state": "Rhode Island"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128777"
    },
    {
      "nct_id": "NCT00572416",
      "title": "Fatigue in Breast Cancer: A Behavioral Sleep Intervention",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Individual Sleep Promotion Plan",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Healthy Eating Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Nebraska",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 220,
      "start_date": "2003-04-01",
      "completion_date": "2006-06-01",
      "has_results": false,
      "last_update_posted_date": "2023-08-31",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00572416"
    },
    {
      "nct_id": "NCT05579444",
      "title": "Systems Biology of Gastrointestinal and Related Diseases",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ulcerative Colitis",
        "Crohn Disease",
        "Obesity",
        "Colon Polyp",
        "Eosinophilic Esophagitis",
        "GERD",
        "Gastro Esophageal Reflux",
        "Barrett Esophagus",
        "Esophageal Cancer",
        "Gastritis",
        "Gastric Ulcer",
        "Duodenal Ulcer",
        "Intestinal Metaplasia",
        "Gastric Cancer",
        "Lymphocytic Colitis",
        "Microscopic Colitis",
        "Celiac Sprue",
        "IBS",
        "Irritable Bowel Syndrome",
        "SIBO",
        "NAFLD",
        "Gallstone Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Viome",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 17,
      "start_date": "2022-11-11",
      "completion_date": "2023-11-29",
      "has_results": false,
      "last_update_posted_date": "2023-12-15",
      "last_synced_at": "2026-05-22T03:07:39.442Z",
      "location_count": 1,
      "location_summary": "Bothell, Washington",
      "locations": [
        {
          "city": "Bothell",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05579444"
    }
  ]
}