{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dose+Finding+Study&page=10", "query": { "condition": "Dose Finding Study", "page": 10 }, "page_size": 10 }, "pagination": { "page": 10, "page_size": 10, "total_count": 868, "total_pages": 87, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dose+Finding+Study&page=11&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dose+Finding+Study&page=9&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-22T14:47:45.456Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00887562", "title": "Study of Idebenone in the Treatment of Mitochondrial Encephalopathy Lactic Acidosis & Stroke-like Episodes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "MELAS Syndrome" ], "interventions": [ { "name": "Idebenone", "type": "DRUG" }, { "name": "Placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Michio Hirano", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "8 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "8 Years to 65 Years" }, "enrollment_count": 27, "start_date": "2009-05", "completion_date": "2012-07", "has_results": true, "last_update_posted_date": "2016-10-26", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00887562" }, { "nct_id": "NCT03345407", "title": "Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "Placebo ELLIPTA", "type": "DRUG" }, { "name": "Nemiralisib ELLIPTA 50 µg", "type": "DRUG" }, { "name": "Nemiralisib ELLIPTA 100 µg", "type": "DRUG" }, { "name": "Nemiralisib ELLIPTA 250 µg", "type": "DRUG" }, { "name": "Nemiralisib ELLIPTA 500 µg", "type": "DRUG" }, { "name": "Nemiralisib ELLIPTA 750 µg", "type": "DRUG" }, { "name": "Albuterol (Salbutamol) MDI or nebules", "type": "DRUG" }, { "name": "Standard of care therapy", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 943, "start_date": "2017-11-28", "completion_date": "2019-01-10", "has_results": true, "last_update_posted_date": "2021-07-14", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 21, "location_summary": "Mobile, Alabama • Colorado Springs, Colorado • Daytona Beach, Florida + 17 more", "locations": [ { "city": "Mobile", "state": "Alabama" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Daytona Beach", "state": "Florida" }, { "city": "St. Petersburg", "state": "Florida" }, { "city": "Adairsville", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT03345407" }, { "nct_id": "NCT01464034", "title": "A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Multiple Myeloma" ], "interventions": [ { "name": "Carfilzomib", "type": "DRUG" }, { "name": "Pomalidomide", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Criterium, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 136, "start_date": "2011-11", "completion_date": "2020-07", "has_results": false, "last_update_posted_date": "2022-08-01", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 9, "location_summary": "Atlanta, Georgia • Indianapolis, Indiana • Hackensack, New Jersey + 5 more", "locations": [ { "city": "Atlanta", "state": "Georgia" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Hackensack", "state": "New Jersey" }, { "city": "New York", "state": "New York" }, { "city": "Durham", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT01464034" }, { "nct_id": "NCT00800176", "title": "A Dose-Finding Study of RO4998452 in Patients With Diabetes Mellitus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus Type 2" ], "interventions": [ { "name": "Placebo", "type": "DRUG" }, { "name": "RO4998452", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 394, "start_date": "2009-01-22", "completion_date": "2009-10-28", "has_results": true, "last_update_posted_date": "2020-11-18", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 11, "location_summary": "Phoenix, Arizona • Los Angeles, California • Palm Springs, California + 8 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Palm Springs", "state": "California" }, { "city": "Bradenton", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00800176" }, { "nct_id": "NCT04137289", "title": "A Study to Find a Safe and Effective Dose of BI 905711 in Patients With Advanced Gastrointestinal Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Gastrointestinal Neoplasms", "Cholangiocarcinoma", "Pancreatic Neoplasms" ], "interventions": [ { "name": "BI 905711", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Boehringer Ingelheim", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 110, "start_date": "2020-03-11", "completion_date": "2023-11-27", "has_results": true, "last_update_posted_date": "2025-03-25", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 4, "location_summary": "New Haven, Connecticut • New York, New York • Houston, Texas + 1 more", "locations": [ { "city": "New Haven", "state": "Connecticut" }, { "city": "New York", "state": "New York" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT04137289" }, { "nct_id": "NCT01586000", "title": "A Dose-finding Study to Evaluate the Effect of a Contraceptive Vaginal Ring, Releasing Nestorone® and Estradiol, on Cycle Control, Ovulation Inhibition, and Pharmacokinetics in Normal Cycling Women", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Suppression of Ovulation" ], "interventions": [ { "name": "10 µg/day E2 with NES 200® µg/day", "type": "DRUG" }, { "name": "20 µg/day E2 with NES 200® µg/day", "type": "DRUG" }, { "name": "40 µg/day E2 with NES 200® µg/day", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Kimberly Myer", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "39 Years", "sex": "FEMALE", "summary": "18 Years to 39 Years · Female only" }, "enrollment_count": 197, "start_date": "2012-03", "completion_date": "2015-05", "has_results": true, "last_update_posted_date": "2025-12-08", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 8, "location_summary": "Baltimore, Maryland • New York, New York • Cincinnati, Ohio + 4 more", "locations": [ { "city": "Baltimore", "state": "Maryland" }, { "city": "New York", "state": "New York" }, { "city": "New York", "state": "New York" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT01586000" }, { "nct_id": "NCT00718692", "title": "Open Label Trial on the Safety and Efficacy of Sym001 in the Treatment of Immune Thrombocytopenic Purpura (ITP)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Immune Thrombocytopenic Purpura" ], "interventions": [ { "name": "Sym001", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Symphogen A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 61, "start_date": "2008-07", "completion_date": "2011-10", "has_results": false, "last_update_posted_date": "2019-01-30", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 3, "location_summary": "Omaha, Nebraska • Philadelphia, Pennsylvania • Charleston, South Carolina", "locations": [ { "city": "Omaha", "state": "Nebraska" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Charleston", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00718692" }, { "nct_id": "NCT00901654", "title": "ACE527 Safety and Immunogenicity Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Enterotoxigenic E. Coli (ETEC) Infection" ], "interventions": [ { "name": "ACE527 vaccine", "type": "BIOLOGICAL" }, { "name": "Placebo vaccine", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "TD Vaccines A/S", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "50 Years", "sex": "ALL", "summary": "18 Years to 50 Years" }, "enrollment_count": 36, "start_date": "2009-06", "completion_date": "2009-11", "has_results": false, "last_update_posted_date": "2010-01-29", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 1, "location_summary": "Baltimore, Maryland", "locations": [ { "city": "Baltimore", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT00901654" }, { "nct_id": "NCT05999799", "title": "A Dose Finding Study to Investigate the Safety and Effectiveness of GSK1070806 in Adult Participants With Moderate to Severe Atopic Dermatitis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dermatitis, Atopic" ], "interventions": [ { "name": "GSK1070806", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 161, "start_date": "2023-11-16", "completion_date": "2025-07-23", "has_results": true, "last_update_posted_date": "2026-06-03", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 17, "location_summary": "Phoenix, Arizona • North Little Rock, Arkansas • Canoga Park, California + 13 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "North Little Rock", "state": "Arkansas" }, { "city": "Canoga Park", "state": "California" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Northridge", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05999799" }, { "nct_id": "NCT01343563", "title": "Trigeminal Nerve Stimulation for Depression: Dose Finding", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Depression" ], "interventions": [ { "name": "Trigeminal Nerve Stimulation", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 20, "start_date": "2011-01", "completion_date": "2012-01", "has_results": false, "last_update_posted_date": "2013-02-06", "last_synced_at": "2026-10-22T14:47:45.456Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01343563" } ] }