{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dose+Finding+Study&page=2", "query": { "condition": "Dose Finding Study", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Dose+Finding+Study&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-06-27T12:49:54.462Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02318329", "title": "Open-Label, Dose-Finding Study Evaluating Safety and PK of FPA144 in Patients With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Solid Tumors", "Gastric Cancer", "Transitional Cell Carcinoma of the Bladder" ], "interventions": [ { "name": "FPA144", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Five Prime Therapeutics, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2014-11", "completion_date": "2019-06-30", "has_results": true, "last_update_posted_date": "2024-06-04", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 13, "location_summary": "Duarte, California • Los Angeles, California • San Francisco, California + 9 more", "locations": [ { "city": "Duarte", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Whittier", "state": "California" }, { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT02318329" }, { "nct_id": "NCT00606684", "title": "A Study To Assess Efficacy And Safety Of Different Doses Of GW642444 In Subjects With Chronic Obstructive Pulmonary Disease (COPD)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pulmonary Disease, Chronic Obstructive" ], "interventions": [ { "name": "GW642444 6.25", "type": "DRUG" }, { "name": "GW642444 3mcg", "type": "DRUG" }, { "name": "GW642444 12.5mcg", "type": "DRUG" }, { "name": "GW642444 25mcg", "type": "DRUG" }, { "name": "GW642444 50mcg", "type": "DRUG" }, { "name": "placebo", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "40 Years to 80 Years" }, "enrollment_count": 602, "start_date": "2008-02", "completion_date": "2008-10", "has_results": true, "last_update_posted_date": "2016-12-16", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 49, "location_summary": "Florence, Alabama • Jasper, Alabama • Montgomery, Alabama + 45 more", "locations": [ { "city": "Florence", "state": "Alabama" }, { "city": "Jasper", "state": "Alabama" }, { "city": "Montgomery", "state": "Alabama" }, { "city": "Fullerton", "state": "California" }, { "city": "Lakewood", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00606684" }, { "nct_id": "NCT00624338", "title": "Atacicept Phase 2/3 in Generalized Systemic Lupus Erythematosus (APRIL-SLE)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Lupus Erythematosus, Systemic" ], "interventions": [ { "name": "Atacicept 75 mg", "type": "DRUG" }, { "name": "Atacicept 150 mg", "type": "DRUG" }, { "name": "Placebo Comparator", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "EMD Serono", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "16 Years", "maximum_age": null, "sex": "ALL", "summary": "16 Years and older" }, "enrollment_count": 461, "start_date": "2008-01", "completion_date": "2012-10", "has_results": true, "last_update_posted_date": "2016-03-14", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 18, "location_summary": "Birmingham, Alabama • Palo Alto, California • San Diego, California + 13 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Upland", "state": "California" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00624338" }, { "nct_id": "NCT05387265", "title": "A Trial to Find Safe and Active Doses for an Investigational Drug, CX-904, for Patients With Advanced Solid Tumors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Solid Tumors" ], "interventions": [ { "name": "CX-904", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "CytomX Therapeutics", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 83, "start_date": "2022-05-16", "completion_date": "2025-06-04", "has_results": false, "last_update_posted_date": "2025-07-14", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 5, "location_summary": "Denver, Colorado • Nashville, Tennessee • Houston, Texas + 2 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "Nashville", "state": "Tennessee" }, { "city": "Houston", "state": "Texas" }, { "city": "San Antonio", "state": "Texas" }, { "city": "Fairfax", "state": "Virginia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05387265" }, { "nct_id": "NCT04641299", "title": "A Study of AZD8233 in Participants With Dyslipidemia", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dyslipidaemia" ], "interventions": [ { "name": "AZD8233", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AstraZeneca", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 119, "start_date": "2020-10-28", "completion_date": "2021-07-20", "has_results": true, "last_update_posted_date": "2022-11-18", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 10, "location_summary": "Roseville, California • Inverness, Florida • Jacksonville, Florida + 7 more", "locations": [ { "city": "Roseville", "state": "California" }, { "city": "Inverness", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Pembroke Pines", "state": "Florida" }, { "city": "Meridian", "state": "Idaho" } ], "official_url": "https://clinicaltrials.gov/study/NCT04641299" }, { "nct_id": "NCT02077933", "title": "Study of Safety and Efficacy of Alpelisib With Everolimus or Alpelisib With Everolimus and Exemestane in Advanced Breast Cancer Patients, Renal Cell Cancer and Pancreatic Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Neoplasms", "Breast Neoplasms", "Kidney Neoplasms", "Pancreatic Neuroendocine Neoplasms (pNETs)" ], "interventions": [ { "name": "alpelisib", "type": "DRUG" }, { "name": "everolimus", "type": "DRUG" }, { "name": "exemestane", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Novartis Pharmaceuticals", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2014-05-14", "completion_date": "2019-04-12", "has_results": false, "last_update_posted_date": "2020-12-08", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 2, "location_summary": "Fayetteville, Arkansas • New York, New York", "locations": [ { "city": "Fayetteville", "state": "Arkansas" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT02077933" }, { "nct_id": "NCT00069264", "title": "Study of E7389 in Patients With Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Solid Tumors" ], "interventions": [ { "name": "E7389", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eisai Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 33, "start_date": "2003-09", "completion_date": "2005-07", "has_results": true, "last_update_posted_date": "2011-12-20", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 2, "location_summary": "The Bronx, New York • San Antonio, Texas", "locations": [ { "city": "The Bronx", "state": "New York" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00069264" }, { "nct_id": "NCT01049893", "title": "Dose Finding, Safety and Tolerability Study for AC220 to Treat Advanced Solid Tumors", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Solid Tumors" ], "interventions": [ { "name": "Compound AC220", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Daiichi Sankyo", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 45, "start_date": "2010-01", "completion_date": "2011-11", "has_results": false, "last_update_posted_date": "2019-02-12", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 2, "location_summary": "Boston, Massachusetts • San Antonio, Texas", "locations": [ { "city": "Boston", "state": "Massachusetts" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01049893" }, { "nct_id": "NCT04064359", "title": "Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Solid Tumor" ], "interventions": [ { "name": "OBT076, a CD205-directed antibody-drug conjugate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Oxford BioTherapeutics Ltd", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2019-07-25", "completion_date": "2027-12-31", "has_results": false, "last_update_posted_date": "2025-09-16", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 10, "location_summary": "Phoenix, Arizona • Los Angeles, California • Santa Monica, California + 7 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Santa Monica", "state": "California" }, { "city": "Tampa", "state": "Florida" }, { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT04064359" }, { "nct_id": "NCT04801849", "title": "Vitamin E Dosing Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Nonalcoholic Fatty Liver Disease", "Nonalcoholic Steatohepatitis" ], "interventions": [ { "name": "Vitamin E", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2022-08-05", "completion_date": "2025-06-30", "has_results": true, "last_update_posted_date": "2026-05-14", "last_synced_at": "2026-06-27T12:49:54.462Z", "location_count": 9, "location_summary": "La Jolla, California • Los Angeles, California • San Francisco, California + 6 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04801849" } ] }