{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Drug+Related+Side+Effects+and+Adverse+Reactions", "query": { "condition": "Drug Related Side Effects and Adverse Reactions" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 336, "total_pages": 34, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?condition=Drug+Related+Side+Effects+and+Adverse+Reactions&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-06-26T16:08:59.949Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT00004176", "title": "Amifostine, Chemotherapy, and Radiation Therapy in Treating Patients With Limited-Stage Small Cell Lung Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Drug/Agent Toxicity by Tissue/Organ", "Lung Cancer", "Radiation Toxicity" ], "interventions": [ { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "cisplatin", "type": "DRUG" }, { "name": "etoposide", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 34, "start_date": "1998-10", "completion_date": "2001-02", "has_results": false, "last_update_posted_date": "2013-05-16", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 4, "location_summary": "Denver, Colorado • St Louis, Missouri • Chapel Hill, North Carolina + 1 more", "locations": [ { "city": "Denver", "state": "Colorado" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Chapel Hill", "state": "North Carolina" }, { "city": "Pittsburgh", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT00004176" }, { "nct_id": "NCT00052884", "title": "Amifostine and Melphalan in Treating Patients With Primary Systemic Amyloidosis Who Are Undergoing Peripheral Stem Cell Transplantation", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Drug/Agent Toxicity by Tissue/Organ", "Multiple Myeloma and Plasma Cell Neoplasm" ], "interventions": [ { "name": "filgrastim", "type": "BIOLOGICAL" }, { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "melphalan", "type": "DRUG" }, { "name": "bone marrow ablation with stem cell support", "type": "PROCEDURE" }, { "name": "peripheral blood stem cell transplantation", "type": "PROCEDURE" } ], "intervention_types": [ "BIOLOGICAL", "DRUG", "PROCEDURE" ], "sponsor": "Eastern Cooperative Oncology Group", "sponsor_class": "NETWORK", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 8, "start_date": "2004-01-22", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2023-06-18", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 16, "location_summary": "Scottsdale, Arizona • Indianapolis, Indiana • Burnsville, Minnesota + 12 more", "locations": [ { "city": "Scottsdale", "state": "Arizona" }, { "city": "Indianapolis", "state": "Indiana" }, { "city": "Burnsville", "state": "Minnesota" }, { "city": "Coon Rapids", "state": "Minnesota" }, { "city": "Edina", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT00052884" }, { "nct_id": "NCT00224952", "title": "Pathogenesis of Adverse Drug Reactions", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Seizures" ], "interventions": [ { "name": "No intervention; Urine Collection", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Children's Mercy Hospital Kansas City", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "1 Year", "maximum_age": "16 Years", "sex": "ALL", "summary": "1 Year to 16 Years" }, "enrollment_count": 274, "start_date": "2002-07", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2017-08-14", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 3, "location_summary": "Louisville, Kentucky • Kansas City, Missouri • Salt Lake City, Utah", "locations": [ { "city": "Louisville", "state": "Kentucky" }, { "city": "Kansas City", "state": "Missouri" }, { "city": "Salt Lake City", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00224952" }, { "nct_id": "NCT07654426", "title": "The CARDIOPROTECT Trial", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diffuse Large B-cell Lymphoma (DLBCL)", "Cardiotoxicity", "Lymphoma" ], "interventions": [ { "name": "Dexrazoxane", "type": "DRUG" }, { "name": "Dexrazoxane placebo", "type": "DRUG" }, { "name": "Doxorubicin", "type": "DRUG" }, { "name": "Liposomal Doxorubicin", "type": "DRUG" }, { "name": "Cyclophosphamide", "type": "DRUG" }, { "name": "Vincristine", "type": "DRUG" }, { "name": "Prednisone", "type": "DRUG" }, { "name": "Rituximab", "type": "DRUG" }, { "name": "Polatuzumab Vedotin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-10-02", "completion_date": "2035-12-31", "has_results": false, "last_update_posted_date": "2026-06-17", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07654426" }, { "nct_id": "NCT01970709", "title": "Diagnosing Adverse Drug Reactions Registry", "overall_status": "UNKNOWN", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Genetics of Drug Metabolism" ], "interventions": [], "intervention_types": [], "sponsor": "Renaissance RX", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 250000, "start_date": "2013-11", "completion_date": null, "has_results": false, "last_update_posted_date": "2015-03-19", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 49, "location_summary": "Birmingham, Alabama • Glendale, Arizona • Peoria, Arizona + 39 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01970709" }, { "nct_id": "NCT03722511", "title": "Evaluating an Amino Acid Based Medical Food w/ Diarrhea in Carcinoid Syndrome & Other NETs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Neuroendocrine Tumors", "Carcinoid Tumor of GI System", "Diarrhea", "Carcinoid Syndrome" ], "interventions": [ { "name": "Amino Acid Based Medical Food/Drink", "type": "DIETARY_SUPPLEMENT" } ], "intervention_types": [ "DIETARY_SUPPLEMENT" ], "sponsor": "Lowell Anthony, MD", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2018-12-06", "completion_date": "2021-05-18", "has_results": false, "last_update_posted_date": "2022-11-03", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT03722511" }, { "nct_id": "NCT02099786", "title": "Randomized Trial Comparison of Ototoxicity Monitoring Programs", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Cisplatin Ototoxicity", "Hearing Loss" ], "interventions": [ { "name": "COMP-VA", "type": "OTHER" }, { "name": "Standard of care", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "VA Office of Research and Development", "sponsor_class": "FED", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 47, "start_date": "2015-04-01", "completion_date": "2018-05-05", "has_results": true, "last_update_posted_date": "2019-10-09", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT02099786" }, { "nct_id": "NCT00003580", "title": "Amifostine to Treat Side Effects of Treatment in Patients Receiving Radiation Therapy and Cisplatin for Advanced Head and Neck Cancer", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Drug/Agent Toxicity by Tissue/Organ", "Head and Neck Cancer", "Oral Complications", "Radiation Toxicity" ], "interventions": [ { "name": "amifostine trihydrate", "type": "DRUG" }, { "name": "cisplatin", "type": "DRUG" }, { "name": "radiation therapy", "type": "RADIATION" } ], "intervention_types": [ "DRUG", "RADIATION" ], "sponsor": "University of Tennessee", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": null, "start_date": "1998-06", "completion_date": "2004-05", "has_results": false, "last_update_posted_date": "2013-06-26", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 1, "location_summary": "Memphis, Tennessee", "locations": [ { "city": "Memphis", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT00003580" }, { "nct_id": "NCT04486573", "title": "Cardiac Effects From Radiation Therapy by MRI", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Radiation Treatment", "Cancer", "Cardiotoxicity" ], "interventions": [ { "name": "Cardiac Magnetic Resonance Imaging", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "University of Colorado, Denver", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "100 Years", "sex": "ALL", "summary": "18 Years to 100 Years" }, "enrollment_count": 6, "start_date": "2020-07-15", "completion_date": "2023-09-14", "has_results": false, "last_update_posted_date": "2024-10-22", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 1, "location_summary": "Aurora, Colorado", "locations": [ { "city": "Aurora", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT04486573" }, { "nct_id": "NCT06699056", "title": "AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Ventricular Ejection Fraction", "LVF", "LV Dysfunction", "Atrial Enlargement", "Conduction Defect", "Heart Failure", "Valvular Heart Disease", "Ischemic Heart Disease", "Cardiotoxicity", "Myocardial Infarction", "Dilated Cardiomyopathy", "HFrEF - Heart Failure With Reduced Ejection Fraction", "HFpEF - Heart Failure With Preserved Ejection Fraction", "Syncope", "Remodeling, Cardiac" ], "interventions": [ { "name": "15-minutes of sitting during COR ECG Acquistion", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Peerbridge Health, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2000, "start_date": "2024-11-21", "completion_date": "2027-11-15", "has_results": false, "last_update_posted_date": "2026-06-01", "last_synced_at": "2026-06-26T16:08:59.949Z", "location_count": 8, "location_summary": "Orange, California • Pasadena, California • Detroit, Michigan + 5 more", "locations": [ { "city": "Orange", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Detroit", "state": "Michigan" }, { "city": "Hackensack", "state": "New Jersey" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06699056" } ] }